Comparing 8501322 FitnessBrowser__Miya:8501322 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 12 hits to proteins with known functional sites (download)
6n2oC 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus with 2-oxoglutarate, coenzyme a and succinyl-coa bound (see paper)
28% identity, 90% coverage: 2:325/361 of query aligns to 187:540/572 of 6n2oC
Sites not aligning to the query:
6n2oA 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus with 2-oxoglutarate, coenzyme a and succinyl-coa bound (see paper)
28% identity, 90% coverage: 2:325/361 of query aligns to 187:540/572 of 6n2oA
Sites not aligning to the query:
6n2nA Crystal structure of 2-oxoglutarate:ferredoxin oxidoreductase from magnetococcus marinus (see paper)
28% identity, 90% coverage: 2:325/361 of query aligns to 187:540/572 of 6n2nA
Q96XT2 2-oxoacid:ferredoxin oxidoreductase 2, subunit alpha; OFOR2; EC 1.2.7.11 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
27% identity, 84% coverage: 12:316/361 of query aligns to 229:573/628 of Q96XT2
5b47A 2-oxoacid:ferredoxin oxidoreductase 2 from sulfolobus tokodai - pyruvate complex (see paper)
27% identity, 84% coverage: 12:316/361 of query aligns to 228:572/627 of 5b47A
5b46A 2-oxoacid:ferredoxin oxidoreductase 2 from sulfolobus tokodai - ligand free form (see paper)
27% identity, 84% coverage: 12:316/361 of query aligns to 228:572/627 of 5b46A
5b48A 2-oxoacid:ferredoxin oxidoreductase 1 from sulfolobus tokodai (see paper)
28% identity, 84% coverage: 13:316/361 of query aligns to 197:524/576 of 5b48A
P72578 2-oxoacid:ferredoxin oxidoreductase subunit alpha; OFOR; EC 1.2.7.11 from Sulfolobus sp. (see 2 papers)
26% identity, 84% coverage: 13:316/361 of query aligns to 229:572/632 of P72578
Q96Y66 2-oxoacid:ferredoxin oxidoreductase 1, subunit alpha; OFOR1; EC 1.2.7.11 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii) (see paper)
26% identity, 84% coverage: 13:316/361 of query aligns to 229:572/627 of Q96Y66
Sites not aligning to the query:
5exeA Crystal structure of oxalate oxidoreductase from moorella thermoacetica bound with carboxy-tpp adduct (see paper)
26% identity, 78% coverage: 16:296/361 of query aligns to 6:301/394 of 5exeA
5exdD Crystal structure of oxalate oxidoreductase from moorella thermoacetica bound with carboxy-di-oxido-methyl-tpp (coom-tpp) intermediate (see paper)
26% identity, 78% coverage: 16:296/361 of query aligns to 6:301/394 of 5exdD
5c4iA Structure of an oxalate oxidoreductase (see paper)
26% identity, 78% coverage: 16:296/361 of query aligns to 6:301/394 of 5c4iA
>8501322 FitnessBrowser__Miya:8501322
MPNNTTDTGTPERIFIKGNEAIAHGALAAGCRCYFGYPITPQNDIPEMMSYALPDAGGEF
VQAESEVASANMLLGAAAAGIRALTSSSSPGISLMQEAISYMAGSELPGVIVNMNRGGPG
LGDIGPSQGDYFQSVKGGGHGDYKLFVLAPATCQECYDMMVQAFDLAFKYRNPVMVLGDA
IVGQMKEPVTPWKPAAVPATEAADWRLEGAKGRKPRLLKSLFLEDGALAGQNRHLQAKYA
AMQAEAKAESFLTDDAELIVVAYGSIGRIAKSAIRKLRAQGHKVGLVRPQTLFPFPGPLL
RGLAEQGKRFLTIEHNCGQMVEDVRLSIRGIVDSAFYGHMPGEMPGSDDFLAPILDAMGG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory