Comparing AO353_03010 FitnessBrowser__pseudo3_N2E3:AO353_03010 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
3ju8A Crystal structure of succinylglutamic semialdehyde dehydrogenase from pseudomonas aeruginosa.
81% identity, 100% coverage: 1:485/487 of query aligns to 2:486/486 of 3ju8A
5u0mA Fatty aldehyde dehydrogenase from marinobacter aquaeolei vt8 and cofactor complex (see paper)
61% identity, 100% coverage: 3:487/487 of query aligns to 5:488/488 of 5u0mA
5u0lA X-ray crystal structure of fatty aldehyde dehydrogenase enzymes from marinobacter aquaeolei vt8 complexed with a substrate (see paper)
61% identity, 100% coverage: 3:487/487 of query aligns to 5:488/488 of 5u0lA
3jz4A Crystal structure of e. Coli NADP dependent enzyme (see paper)
34% identity, 94% coverage: 6:462/487 of query aligns to 14:471/481 of 3jz4A
P25526 Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli (strain K12) (see paper)
34% identity, 94% coverage: 6:462/487 of query aligns to 15:472/482 of P25526
5izdA Wild-type glyceraldehyde dehydrogenase from thermoplasma acidophilum in complex with NADP
31% identity, 84% coverage: 3:410/487 of query aligns to 4:415/494 of 5izdA
Sites not aligning to the query:
Q9H2A2 2-aminomuconic semialdehyde dehydrogenase; Aldehyde dehydrogenase 12; Aldehyde dehydrogenase family 8 member A1; EC 1.2.1.32 from Homo sapiens (Human) (see paper)
31% identity, 94% coverage: 5:462/487 of query aligns to 13:476/487 of Q9H2A2
4cazA Crystal structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa in complex with nadh
32% identity, 93% coverage: 2:453/487 of query aligns to 6:462/489 of 4cazA
Sites not aligning to the query:
2woxA Betaine aldehyde dehydrogenase from pseudomonas aeruginosa with NAD(p) h-catalytic thiol adduct. (see paper)
32% identity, 93% coverage: 2:453/487 of query aligns to 6:462/489 of 2woxA
Sites not aligning to the query:
2wmeA Crystallographic structure of betaine aldehyde dehydrogenase from pseudomonas aeruginosa (see paper)
32% identity, 93% coverage: 2:453/487 of query aligns to 6:462/489 of 2wmeA
Sites not aligning to the query:
Q9HTJ1 NAD/NADP-dependent betaine aldehyde dehydrogenase; BADH; EC 1.2.1.8 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
32% identity, 93% coverage: 2:453/487 of query aligns to 7:463/490 of Q9HTJ1
Sites not aligning to the query:
8vr1A Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (ctp bound)
33% identity, 92% coverage: 4:453/487 of query aligns to 7:461/488 of 8vr1A
8vr0A Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (gmp bound)
33% identity, 92% coverage: 4:453/487 of query aligns to 7:461/488 of 8vr0A
8vqzA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (cmp bound)
33% identity, 92% coverage: 4:453/487 of query aligns to 7:461/488 of 8vqzA
8vqwC Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (coa bound)
33% identity, 92% coverage: 4:453/487 of query aligns to 7:461/488 of 8vqwC
8vj3A Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (fad bound)
33% identity, 92% coverage: 4:453/487 of query aligns to 7:461/488 of 8vj3A
8uzoA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (adp bound)
33% identity, 92% coverage: 4:453/487 of query aligns to 7:461/488 of 8uzoA
8uznA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (amp bound)
33% identity, 92% coverage: 4:453/487 of query aligns to 7:461/488 of 8uznA
8uzmA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (NADPH bound)
33% identity, 92% coverage: 4:453/487 of query aligns to 7:461/488 of 8uzmA
8uzkA Crystal structure of betaine aldehyde dehydrogenase (betb) from klebsiella aerogenes (NADP+ bound)
33% identity, 92% coverage: 4:453/487 of query aligns to 7:461/488 of 8uzkA
>AO353_03010 FitnessBrowser__pseudo3_N2E3:AO353_03010
MNSLYIAGEWLAGQGDMFESLNPVTQQVLWSGQGASAAQVESAVQAARQAFPAWAKRSLE
DRIGVLETFAASLKKHADELAHCIGEETGKPLWEAATEVTSMVNKIAISVQSYRERTGEK
SGPLGDATAVLRHKPHGVVAVFGPYNFPGHLPNGHIVPALLAGNSVLFKPSELTPKVAEL
TVKCWIEAGLPAGVLNLLQGARETGIALAANPGIDGLFFTGSSRTGNHLHAQFSGRPDKI
LALEMGGNNPLVVDQVADLDAAVYTIIQSAFISAGQRCTCARRLLVPQGAWGDTLLARLV
AVSATIDVGAFDQQPAPFMGSVVSLAAAKALMDAQEHLLANGAVPLLKMTQPQANAALLT
PGILDVSAVTDRPDEELFGPLLQVIRYADFEAAIAEANNTQYGLAAGLLSDSEARYQQFW
LESRAGIVNWNKQLTGAASSAPFGGVGASGNHRASAYYAADYCAYPVASLETPSLTLPAA
LTPGVRM
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory