Comparing AO353_04350 FitnessBrowser__pseudo3_N2E3:AO353_04350 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 10 hits to proteins with known functional sites (download)
4f4fA X-ray crystal structure of plp bound threonine synthase from brucella melitensis
58% identity, 99% coverage: 1:462/469 of query aligns to 2:461/464 of 4f4fA
1kl7A Crystal structure of threonine synthase from yeast (see paper)
43% identity, 90% coverage: 3:426/469 of query aligns to 7:462/509 of 1kl7A
Q42598 Threonine synthase; TS; EC 4.2.3.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
43% identity, 90% coverage: 1:423/469 of query aligns to 5:462/514 of Q42598
8g1yA Crystal structure of the threonine synthase from streptococcus pneumoniae in complex with pyridoxal 5-phosphate.
37% identity, 91% coverage: 1:428/469 of query aligns to 5:444/496 of 8g1yA
1vb3A Crystal structure of threonine synthase from escherichia coli
33% identity, 99% coverage: 1:462/469 of query aligns to 1:427/428 of 1vb3A
2c2bA Crystallographic structure of arabidopsis thaliana threonine synthase complexed with pyridoxal phosphate and s-adenosylmethionine (see paper)
24% identity, 68% coverage: 99:419/469 of query aligns to 115:406/444 of 2c2bA
Sites not aligning to the query:
Q9S7B5 Threonine synthase 1, chloroplastic; Protein METHIONINE OVER-ACCUMULATOR 2; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
24% identity, 68% coverage: 99:419/469 of query aligns to 190:481/526 of Q9S7B5
Sites not aligning to the query:
6nmxA Threonine synthase from bacillus subtilis atcc 6633 with plp and appa (see paper)
28% identity, 41% coverage: 71:262/469 of query aligns to 12:193/350 of 6nmxA
Sites not aligning to the query:
6cgqB Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala (see paper)
28% identity, 41% coverage: 71:262/469 of query aligns to 10:191/345 of 6cgqB
Sites not aligning to the query:
6cgqA Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala (see paper)
28% identity, 41% coverage: 71:262/469 of query aligns to 8:183/339 of 6cgqA
Sites not aligning to the query:
>AO353_04350 FitnessBrowser__pseudo3_N2E3:AO353_04350
MRYISTRGQAPALNFEDVLLAGLASDGGLYVPENLPRFTQEEIASWAGLPYHELAFRVMR
PFVSGSIPDADFKKILEETYGVFSHSAVAPLRQLNSNEWVLELFHGPTLAFKDFALQLLG
RLLDYVLEKRGERVVIVGATSGDTGSAAIEGCKHCENVDIFILHPHNRVSEVQRRQMTTI
FGENIHNIAIEGNFDDCQEMVKASFADQSFLKGTRLVAVNSINWARIMAQIVYYFHAALQ
LGGPARSVSFSVPTGNFGDIFAGYLARNMGLPINQLIVATNRNDILHRFMSGNQYVKETL
HATLSPSMDIMVSSNFERLLFDLHGRNGAAIAGLMDTFKQGGGFSVEQERWTEARKLFDS
LAVDDAQTCETIAEVFEQTGELLDPHTAIGVKAARECRRSLDIPMVILGTAHPVKFPEAV
EKAGVGKALELPAHLSDLFERDERCTVLPNDLKAVQAFVSQHGNRGKPL
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory