SitesBLAST

D57 (= D36) mutation to A: Loss of transport activity.; mutation to E: Retains 50% of its transport activity.
R103 (= R89) mutation to A: Loss of transport activity.
W309 (= W305) mutation to V: Loss of transport activity.
D312 (= D308) mutation to A: Loss of transport activity.
R313 (= R309) mutation to A: Loss of transport activity.

Sites not aligning to the query:

54 D→A: Loss of transport activity.; D→E: Retains 50% of its transport activity.
317 mutation I->H,Y: Loss of transport activity.
386 R→A: Loss of transport activity.

O15245 Solute carrier family 22 member 1; Organic cation transporter 1; hOCT1 from Homo sapiens (Human) (see 10 papers)
25% identity, 73% coverage: 79:399/438 of query aligns to 162:487/554 of O15245

query
sites
O15245

G

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S189 (≠ C106) to L: no changes in MPP(+) uptake; dbSNP:rs34104736
G220 (≠ A145) to V: affects transporter activity; reduction of MPP(+) uptake when associated with V-408; dbSNP:rs36103319
Y240 (≠ P165) mutation to F: Decreased TEA uptake.
P283 (= P200) to L: in dbSNP:rs4646277; mutation to A: Decreased TEA uptake.
R287 (vs. gap) to G: in dbSNP:rs4646278
P341 (≠ M249) to L: affects transporter activity; reduction of TEA uptake; reduction o MPP(+) uptake when associated with V-408; largely localized to the plasma membrane; dbSNP:rs2282143
R342 (≠ L250) to H: no changes in MPP(+) uptake when associated with V-408; dbSNP:rs34205214
Y361 (≠ F269) mutation to F: Decreased TEA uptake.
Y376 (≠ F285) mutation to F: Decreased TEA uptake.
G401 (= G311) to S: affects transporter activity; reduction of MPP(+), serotonin and TEA uptake; no MPP(+) uptake when associated with L-160; dbSNP:rs34130495
M408 (≠ I318) to V: does not affect transporter activity; no changes in MPP(+) uptake when associated with F-14; no changes in MPP(+) uptake when associated with F-85; no changes in MPP(+) uptake when associated with L-189; no changes in MPP(+) uptake when associated with H-342; no changes in MPP(+) uptake when associated with M-420 del; no changes in MPP(+) uptake when associated with I-440; no changes in MPP(+) uptake when associated with I-461; no changes in MPP(+) uptake when associated with M-488; reduction of MPP uptake when associated with C-61; no MPP(+) uptake when associated with V-220; reduction of MPP(+) uptake when associated with L-341; no MPP(+) uptake when associated with S-401; no MPP(+) uptake when associated with R-465; dbSNP:rs628031
M420 (= M330) natural variant: Missing (reduction of serum O-isobutanoyl-(R)-carnitine levels; no change in MPP(+) uptake; no changes in MPP(+) uptake when associated with V-408; dbSNP:rs72552763)
M440 (= M353) to I: in dbSNP:rs35956182
V461 (= V372) to I: no changes in MPP(+) uptake when associated with V-408; dbSNP:rs34295611
G465 (= G376) to R: reduction of the localization to the basolateral membrane; no MPP(+) uptake when associated with V-408; dbSNP:rs34059508; mutation to A: No changes in MPP(+) uptake.

Sites not aligning to the query:

14 S → F: exclusively found in the African American population; increased MPP(+) uptake when associated with V-408; dbSNP:rs34447885
24 I→L: No change in fenoterol uptake. No change in trospium uptake. No change in terbutaline uptake.
28 L→I: No change in fenoterol uptake. No change in trospium uptake. No change in terbutaline uptake.
31 A→S: No change in fenoterol uptake. No change in trospium uptake. No change in terbutaline uptake.
32 F→L: No change in fenoterol uptake. Decreased trospium uptake. Decreased trospium affinity.
36 C→Y: Increased fenoterol uptake. Increased fenoterol affinity. No change in trospium uptake. No change in terbutaline uptake. No change in terbutaline affinity.
41 F → L: in dbSNP:rs2297373
61 R → C: affects transporter activity; reduction of MPP(+) uptake; reduction of serum O-isobutanoyl-(R)-carnitine levels; reduction of MPP(+) uptake when associated with V-408; dbSNP:rs12208357
85 L → F: no changes in MPP(+) uptake; when associated with V-408; dbSNP:rs35546288
88 C → R: affects transporter activity; reduction of MPP(+), serotonin and TEA uptake; dbSNP:rs55918055
160 L → F: no changes in both MPP(+) and TEA uptake; abolishes MPP(+) uptake when associated with S-401; largely localized to the plasma membrane; dbSNP:rs683369
488 R → M: no changes in MPP(+) uptake when associated with V-408; dbSNP:rs35270274

A0A0H2VG78 Glucose transporter GlcP; Glucose/H(+) symporter from Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) (see paper)
24% identity, 82% coverage: 78:437/438 of query aligns to 57:433/446 of A0A0H2VG78

query
sites
A0A0H2VG78

L

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R102 (= R131) mutation to A: Loss of transport activity.
I105 (≠ Q134) mutation to S: Affects symport activity. May function as an uniporter.
E122 (= E151) mutation to A: Loss of transport activity.
Q137 (= Q166) mutation to A: Loss of transport activity.
Q250 (vs. gap) mutation to A: Loss of transport activity.
Q251 (vs. gap) mutation to A: Loss of transport activity.
N256 (vs. gap) mutation to A: Loss of transport activity.
W357 (≠ G361) mutation to A: Loss of transport activity.

Sites not aligning to the query:

22 D→N: Affects symport activity. May function as an uniporter.

8et8A Cryo-em structure of the organic cation transporter 1 in complex with verapamil (see paper)
24% identity, 81% coverage: 78:430/438 of query aligns to 160:516/532 of 8et8A

query
sites
8et8A

L

L

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A

L

Y

C

N

D

L

L

G

G

I

I

V

I

G

-

A

-

S

-

A

-

A

T

P

P

F

F

F

L

A

V

Q

F

K

R

L

L

V

M

A

E

M

V

G

-

L

-

S

-

W

W

V

Q

G

G

G

L

Y

P

V

L

S

I

A

L

A

F

A

T

V

V

I

V

S

G

L

L

I

V

A

A

-

G

-

M

V

T

L

L

C

L

L

L

K

P

E

E

T

T

R

K

binding (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile: K213 (≠ G139), W216 (= W142), Q240 (= Q166), W353 (≠ L262), Y360 (≠ F269), F378 (≠ E283), S381 (≠ L286), E385 (≠ C290), C449 (≠ G361), S469 (= S378)

Sites not aligning to the query:

binding (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile: 31, 35

8et7A Cryo-em structure of the organic cation transporter 1 in complex with diphenhydramine (see paper)
24% identity, 81% coverage: 78:430/438 of query aligns to 160:516/532 of 8et7A

query
sites
8et7A

L

L

G

G

S

S

A

L

L

G

F

V

G

G

H

Y

F

I

G

A

D

D

R

R

I

F

G

G

R

R

K

K

S

L

T

C

L

L

V

L

A

A

S

T

L

T

L

L

L

I

M

S

G

A

V

V

C

S

T

G

T

V

L

L

I

M

G

A

V

V

L

A

P

P

G

D

Y

Y

E

T

S

S

I

-

G

-

A

-

W

-

A

-

P

-

I

-

L

-

L

M

C

L

V

L

L

F

R

R

F

L

G

L

Q

Q

G

G

L

L

G

V

L

S

G

K

G

G

E

S

W

W

G

M

G

S

A

G

A

Y

L

T

L

L

A

I

T

T

E

E

N

F

A

V

P

G

K

S

G

G

K

Y

R

R

A

R

W

T

F

V

G

A

M

I

F

L

P

Y

Q

Q

L

M

G

A

P

F

S

T

I

V

G

G

F

L

L

V

A

L

N

S

G

G

L

V

-

A

-

Y

-

A

-

I

-

P

-

H

-

W

-

R

F

W

L

L

T

Q

L

L

A

A

M

V

T

S

L

L

N

P

D

T

E

F

Q

L

F

F

R

L

S

L

W

Y

G

Y

W

W

R

C

I

V

P

P

-

E

-

S

-

P

-

R

F

W

L

L

S

S

A

Q

V

K

L

R

V

N

M

T

V

Q

G

A

L

I

Y

K

V

I

R

M

L

D

K

H

L

I

H

A

E

Q

T

K

-

N

-

G

-

K

-

L

-

P

P

P

V

A

F

D

A

L

N

K

A

M

M

L

A

S

R

L

Q

K

E

E

R

D

V

S

K

T

I

E

P

K

L

L

V

S

E

P

L

S

F

F

S

A

Q

D

Y

L

W

F

A

R

P

T

M

P

L

Q

L

L

G

R

A

K

A

H

A

T

M

F

V

I

V

L

C

M

Y

Y

A

L

L

W

F

F

Y

T

I

S

S

S

T

V

V

L

F

Y

S

Q

-

G

L

L

S

I

Y

M

G

H

V

M

S

G

T

A

L

T

G

G

-

G

-

N

-

L

Y

Y

S

L

R

D

E

F

T

F

F

Y

L

S

G

A

L

L

L

V

C
x
E

F

F

A

P

V

A

L

A

F

F

M

I

A

I

A

L

A

V

T

T

P

-

L

-

S

-

A

-

W

-

A

-

S

I

D

D

R

R

F

V

G

G

R

R

K

I

P

Y

V

P

L

L

I

A

I

V

G

S

G

N

V

L

L

V

A

A

I

G

L

A

S

A

G

C

F

L

T

I

M

M

E

-

P

I

L

F

L

I

T

S

H

Q

G

D

T

L

T

H

W

W

G

L

V

N

A

I

L

T

F

V

L

A

C

C

I

V

E

G

L

R

F

M

L

G

M

I

G

T

V

I

T

V

F
|
F

A

Q

P

M

M

V

G

C

A

L

L

V

L

N

P

A

E

E

L

L

F

Y

P

P

T

T

R

F

V

I

R

R

Y

N

T

L

G

G

-

V

-

M

-

V

A

C

S

S

A

S

A

L

Y

C

N

D

L

L

G

G

I

I

V

I

G

-

A

-

S

-

A

-

A

T

P

P

F

F

F

L

A

V

Q

F

K

R

L

L

V

M

A

E

M

V

G

-

L

-

S

-

W

W

V

Q

G

G

G

L

Y

P

V

L

S

I

A

L

A

F

A

T

V

V

I

V

S

G

L

L

I

V

A

A

-

G

-

M

V

T

L

L

C

L

L

L

K

P

E

E

T

T

R

K

binding n-[2-(benzhydryloxy)ethyl]-n,n-dimethylamine: E385 (≠ C290), F445 (= F357)

Sites not aligning to the query:

binding n-[2-(benzhydryloxy)ethyl]-n,n-dimethylamine: 35

Q9R0W2 Solute carrier family 22 member 2; Organic cation transporter 2; rOCT2 from Rattus norvegicus (Rat) (see paper)
30% identity, 28% coverage: 78:200/438 of query aligns to 162:284/555 of Q9R0W2

query
sites
Q9R0W2

L

I

G

G

S

A

A

M

L

M

F

I

G

G

H

Y

F

L

G

A

D

D

R

R

I

F

G

G

R

R

K

K

S

F

T

C

L

L

V

L

A

V

S

T

L

I

L

L

L

I

M

N

G

A

V

I

C

S

T

G

T

A

L

L

I

M

G

A

V

I

L

S

P

P

G

N

Y

Y

E

-

S

-

I

-

G

-

A

A

W

W

A

-

P

-

I

-

L

-

L

M

C

L

V

V

L

F

R

R

F

F

G

L

Q

Q

G

G

L

L

G

V

L

S

G

K

G

A

E

G

W

W

G

L

G

I

A

G

A

Y

L

I

L

L

A

I

T

T

E

E

N

F

A

V

P

G

K

L

G

G

K

Y

R

R

A

R

W

M

F

V

G

G

M

I

F

C

P

Y

Q

Q

L

I

G

A

P

F

S

T

I

V

G

G

F

L

L

L

A

I

A

L

N

A

G

G

L

V

-

A

-

Y

-

V

-

I

-

P

-

N

-

W

-

R

F

W

L

L

T

Q

L

F

A

A

M

V

T

T

L

L

N

P

D

N

E

F

Q

C

F

F

R

L

S

L

W

Y

G

F

W

W

R

C

I

I

P

P

Sites not aligning to the query:

451 Involved in recognition of organic cations and participates in structural changes that occur during translocation of organic cations; C→M: Transport activity strongly reduced.

8sc2A Human oct1 bound to diltiazem in inward-open conformation (see paper)
30% identity, 28% coverage: 79:200/438 of query aligns to 144:265/453 of 8sc2A

query
sites
8sc2A

G

G

S

S

A

L

L

G

F

V

G

G

H

Y

F

F

G

A

D

D

R

R

I

F

G

G

R

R

K

K

S

L

T

C

L

L

V

L

A

G

S

T

L

V

L

L

L

V

M

N

G

A

V

V

C

S

T

G

T

V

L

L

I

M

G

A

V

F

L

S

P

P

G

N

Y

Y

E

M

S

S

I

-

G

-

A

-

W

-

A

-

P

-

I

-

L

-

L

M

C

L

V

L

L

F

R

R

F

L

G

L

Q

Q

G

G

L

L

G

V

L

S

G

K

G

G

E

N

W
|
W

G

M

G

A

A

G

A

Y

L

T

L

L

A

I

T

T

E

E

N

F

A

V

P

G

K

S

G

G

K

S

R

R

A

R

W

T

F

V

G

A

M

I

F

M

P

Y

Q
|
Q

L

M

G

A

P
x
F

S

T

I

V

G

G

F

L

L

V

A

A

A

L

N

T

G

G

L

L

-

A

-

Y

-

A

-

L

-

P

-

H

-

W

-

R

F

W

L

L

T

Q

L

L

A

A

M

V

T

S

L

L

N

P

D

T

E

F

Q

L

F

F

R

L

S

L

W

Y

G

Y

W

W

R

C

I

V

P

P

binding Diltiazem: W199 (= W142), Q223 (= Q166), F226 (≠ P169)

Sites not aligning to the query:

binding Diltiazem: 18, 293, 297, 385

Q9Y7Q9 Probable metabolite transporter C2H8.02 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
27% identity, 34% coverage: 78:227/438 of query aligns to 98:254/583 of Q9Y7Q9

query
sites
Q9Y7Q9

L

M

G

G

S

Q

A

L

L

L

F

F

G

G

H

F

F

L

G

G

D

D

R

F

I

F

G

G

R

R

K

K

S

F

T

V

L

Y

V

G

A

K

S

E

L

M

L

V

M

V

G

I

V

I

C

A

T

T

T

I

L

L

I

I

G

I

V

C

L

L

P

P

G

D

Y

R

E

I

S

P

I

T

G

P

A

T

W

A

A

K

P

M

I

M

L

W

L

L

C

F

V

A

L

F

R

R

F

V

G

M

Q

L

G

G

L

I

G

G

L

I

G

G

E

D

W

Y

G

P

G

M

A

S

A

A

L

S

L

I

A

T

T

S

E

E

N

Q

A

S

P

L

K

I

G

N

K

R

R

R

-

G

-

A

-

L

A

A

W

W

F

I

G

F

M

S

F

N

P

Q

Q

G

L

W

G

G

P

T

S

L

I

A

G

G

F

C

L

V

A

A

A

T

N

L

G

I

L

I

F

L

L

A

T

C

L

F

A

E

M

K

T

P

L

L

N

N

D

D

-

R

-

G

E

E

Q

Y

F

T

R

K

S

L

W

N

G

G

-

V

W

W

R

R

I

I

P

Q

F

F

L

G

L

I

S

A

A

L

V

F

L

P

V

A

M

V

V

I

G

V

L

L

Y

I

V

P

R

R

L

L

K

R

L

M

H

Q

E

E

T

S

P

E

V

Q

F

F

A

K

N

N

A

S

Sites not aligning to the query:

267 modified: Phosphoserine
269 modified: Phosphoserine
289 modified: Phosphoserine
290 modified: Phosphoserine
292 modified: Phosphoserine
330 modified: Phosphoserine

8sc3A Human oct1 bound to fenoterol in inward-open conformation (see paper)
32% identity, 23% coverage: 79:179/438 of query aligns to 144:236/445 of 8sc3A

query
sites
8sc3A

G

G

S

S

A

L

L

G

F

V

G

G

H

Y

F

F

G

A

D

D

R

R

I

F

G

G

R

R

K

K

S

L

T

C

L

L

V

L

A

G

S

T

L

V

L

L

L

V

M

N

G

A

V

V

C

S

T

G

T

V

L

L

I

M

G

A

V

F

L

S

P

P

G

N

Y

Y

E

M

S

S

I

-

G

-

A

-

W

-

A

-

P

-

I

-

L

-

L

M

C

L

V

L

L

F

R

R

F

L

G

L

Q

Q

G

G

L

L

G

V

L

S

G

K

G

G

E

N

W
|
W

G
x
M

G

A

A

G

A

Y

L

T

L

L

A

I

T

T

E

E

N

F

A

V

P

G

K

S

G

G

K

S

R

R

A

R

W

T

F

V

G

A

M

I

F

M

P

Y

Q
|
Q

L

M

G

A

P
x
F

S

T

I

V

G

G

F

L

L

V

A

A

A

L

N

T

G

G

L

L

binding Fenoterol: W199 (= W142), M200 (≠ G143), Q223 (= Q166), F226 (≠ P169)

Sites not aligning to the query:

binding Fenoterol: 284, 291, 376, 380

8sc6A Human oct1 bound to thiamine in inward-open conformation (see paper)
32% identity, 23% coverage: 79:179/438 of query aligns to 144:236/447 of 8sc6A

query
sites
8sc6A

G

G

S

S

A

L

L

G

F

V

G

G

H

Y

F

F

G

A

D

D

R

R

I

F

G

G

R

R

K

K

S

L

T

C

L

L

V

L

A

G

S

T

L

V

L

L

L

V

M

N

G

A

V

V

C

S

T

G

T

V

L

L

I

M

G

A

V

F

L

S

P

P

G

N

Y

Y

E

M

S

S

I

-

G

-

A

-

W

-

A

-

P

-

I

-

L

-

L

M

C

L

V

L

L

F

R

R

F

L

G

L

Q

Q

G

G

L

L

G

V

L

S

G

K

G

G

E

N

W

W

G

M

G

A

A

G

A

Y

L

T

L

L

A

I

T

T

E

E

N

F

A

V

P

G

K

S

G

G

K

S

R

R

A

R

W

T

F

V

G

A

M

I

F

M

P

Y

Q
|
Q

L

M

G

A

P
x
F

S

T

I

V

G

G

F

L

L

V

A

A

A

L

N

T

G

G

L

L

binding 3-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium: Q223 (= Q166), F226 (≠ P169)

Sites not aligning to the query:

binding 3-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium: 293, 294, 318, 378, 379

Q9VCA2 Organic cation transporter protein from Drosophila melanogaster (Fruit fly) (see paper)
29% identity, 38% coverage: 78:244/438 of query aligns to 143:302/548 of Q9VCA2

query
sites
Q9VCA2

L

L

G

G

S

S

A

L

L

I

F

F

G

G

H

Q

F

M

G

S

D

D

R

K

I

L

G

G

R

R

K

K

S

P

T

T

L

F

V

F

A

A

S

S

L

L

L

V

L

L

M

Q

G

L

V

I

C

F

T

G

T

V

L

L

I

A

G

A

V

V

L

A

P

P

G

E

Y

Y

E

F

S

S

I

-

G

-

A

-

W

-

A

-

P

-

I

-

L

-

L

Y

C

T

V

I

L

S

R

R

F

M

G

I

Q

V

G

G

L

A

G

T

L

T

G

S

G

G

E

V

W

F

G

L

G

V

A

A

A

Y

L

V

L

I

A

A

T

L

E

E

N

M

A

V

P

G

K

S

G

S

K

Y

R

R

A

L

W

F

F

A

G

G

M

V

F

A

P

M

Q

Q

L

M

G

F

P

F

S

S

I

V

G

G

F

F

L

M

A

L

A

T

N

A

G

G

L

F

-

A

-

Y

-

F

-

I

-

H

-

D

-

W

-

R

F

W

L

L

T

Q

L

I

A

A

M

I

T

T

L

L

N

P

D

G

E

L

Q

L

F

F

R

L

S

C

W

Y

G

Y

W

W

R

I

I

I

P

P

F

-

L

E

L

S

S

A

A

R

V

W

L

L

V

L

M

M

V

K

G

G

L

-

Y

-

V

-

R

-

L

-

K

R

L

K

H

D

E

E

T

A

P

F

V

V

F

I

A

I

N

E

A

K

M

A

A

A

R

K

Q

E

E

N

R

K

V

V

K

E

I

V

P

P

L

-

V

N

E

E

L

I

F

Y

S

E

Q

Q

Sites not aligning to the query:

97 modified: carbohydrate, N-linked (GlcNAc...) asparagine

8et9A Cryo-em structure of the organic cation transporter 2 in complex with 1-methyl-4-phenylpyridinium (see paper)
31% identity, 28% coverage: 78:200/438 of query aligns to 160:282/517 of 8et9A

query
sites
8et9A

L

V

G

G

S

S

A

M

L

S

F

I

G

G

H

Y

F

I

G

A

D

D

R

R

I

F

G

G

R

R

K

K

S

L

T

C

L

L

V

L

A

V

S

T

L

I

L

L

L

I

M

N

G

A

V

I

C

S

T

G

T

V

L

L

I

M

G

A

V

V

L

A

P

P

G

N

Y

Y

E

-

S

-

I

-

G

-

A

T

W

W

A

-

P

-

I

-

L

-

L

M

C

L

V

I

L

F

R

R

F

L

G

I

Q

Q

G

G

L

L

G

V

L

S

G

K

G

G

E

G

W
|
W

G

L

G

I

A

G

A

Y

L

T

L

L

A

P

T

T

E

E

N

F

A

V

P

G

K

L

G

E

K

Y

R

R

A

R

W

T

F

V

G

G

M

I

F

L

P

Y

Q
|
Q

L

M

G

A

P
x
F

S

S

I

V

G

G

F

L

L

L

A

V

A

L

N

A

G

G

L

V

-

A

-

Y

-

A

-

I

-

P

-

H

-

W

-

R

F

W

L

L

T

Q

L

L

A

A

M

V

T

T

L

L

N

P

D

N

E

F

Q

F

F

F

R

L

S

L

W

Y

G

Y

W

W

R

C

I

I

P

P

binding 1-methyl-4-phenylpyridin-1-ium: W216 (= W142), Q240 (= Q166), F243 (≠ P169)

Sites not aligning to the query:

binding 1-methyl-4-phenylpyridin-1-ium: 430

Query Sequence

>AO353_04405 AO353_04405 MFS transporter
MTTSTTYSDAVPAQPTNSTTRVATASFIGTAIEFYDFYVYATAAALVIGPVFFPQTSGTA
QMLSAFLTFGIAFLARPLGSALFGHFGDRIGRKSTLVASLLLMGVCTTLIGVLPGYESIG
AWAPILLCVLRFGQGLGLGGEWGGAALLATENAPKGKRAWFGMFPQLGPSIGFLAANGLF
LTLAMTLNDEQFRSWGWRIPFLLSAVLVMVGLYVRLKLHETPVFANAMARQERVKIPLVE
LFSQYWAPMLLGAAAMVVCYALFYISTVFSLSYGVSTLGYSRETFLGLLCFAVLFMAAAT
PLSAWASDRFGRKPVLIIGGVLAILSGFTMEPLLTHGTTWGVALFLCIELFLMGVTFAPM
GALLPELFPTRVRYTGASAAYNLGGIVGASAAPFFAQKLVAMGGLSWVGGYVSAAAVISL
IAVLCLKETRHNDLNQVA

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory