Comparing AO353_05935 FitnessBrowser__pseudo3_N2E3:AO353_05935 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P83788 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Pseudomonas fluorescens (see paper)
89% identity, 100% coverage: 1:416/416 of query aligns to 1:416/416 of P83788
1qz9A The three dimensional structure of kynureninase from pseudomonas fluorescens (see paper)
89% identity, 97% coverage: 3:405/416 of query aligns to 2:404/404 of 1qz9A
P70712 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Rattus norvegicus (Rat) (see paper)
27% identity, 94% coverage: 8:400/416 of query aligns to 31:459/464 of P70712
Sites not aligning to the query:
3e9kA Crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex (see paper)
28% identity, 94% coverage: 8:400/416 of query aligns to 26:445/446 of 3e9kA
2hzpA Crystal structure of homo sapiens kynureninase (see paper)
28% identity, 94% coverage: 8:400/416 of query aligns to 26:446/447 of 2hzpA
Q16719 Kynureninase; L-kynurenine hydrolase; EC 3.7.1.3 from Homo sapiens (Human) (see 4 papers)
28% identity, 94% coverage: 8:400/416 of query aligns to 31:459/465 of Q16719
Sites not aligning to the query:
P96060 2-aminoethylphosphonate--pyruvate transaminase; 2-aminoethylphosphonate aminotransferase; AEP transaminase; AEPT; EC 2.6.1.37 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
27% identity, 49% coverage: 64:265/416 of query aligns to 26:224/367 of P96060
Sites not aligning to the query:
1m32B Crystal structure of 2-aminoethylphosphonate transaminase (see paper)
27% identity, 49% coverage: 64:265/416 of query aligns to 22:220/362 of 1m32B
Sites not aligning to the query:
1m32A Crystal structure of 2-aminoethylphosphonate transaminase (see paper)
27% identity, 49% coverage: 64:265/416 of query aligns to 21:219/361 of 1m32A
Sites not aligning to the query:
1vjoA Crystal structure of alanine--glyoxylate aminotransferase (alr1004) from nostoc sp. At 1.70 a resolution (see paper)
31% identity, 25% coverage: 134:238/416 of query aligns to 103:216/377 of 1vjoA
Sites not aligning to the query:
2yrrA Hypothetical alanine aminotransferase (tth0173) from thermus thermophilus hb8
30% identity, 38% coverage: 78:234/416 of query aligns to 40:193/352 of 2yrrA
2yriA Crystal structure of alanine-pyruvate aminotransferase with 2- methylserine
30% identity, 38% coverage: 78:234/416 of query aligns to 40:193/352 of 2yriA
Sites not aligning to the query:
7tlmA Structure of atopobium parvulum sufs (see paper)
21% identity, 70% coverage: 29:319/416 of query aligns to 27:318/415 of 7tlmA
Q93WX6 Cysteine desulfurase 1, chloroplastic; NIFS-like protein 1; CpNifS1; Plastid sufS-like protein; Protein AtCpNifS; Selenocysteine lyase; EC 2.8.1.7; EC 4.4.1.16 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
21% identity, 81% coverage: 21:356/416 of query aligns to 65:403/463 of Q93WX6
Sites not aligning to the query:
P0A6B7 Cysteine desulfurase IscS; NifS protein homolog; ThiI transpersulfidase; TusA transpersulfidase; EC 2.8.1.7 from Escherichia coli (strain K12) (see 4 papers)
28% identity, 34% coverage: 78:219/416 of query aligns to 56:198/404 of P0A6B7
Sites not aligning to the query:
P0A6B9 Cysteine desulfurase IscS; EC 2.8.1.7 from Escherichia coli O157:H7 (see paper)
28% identity, 34% coverage: 78:219/416 of query aligns to 56:198/404 of P0A6B9
Sites not aligning to the query:
3lvmB Crystal structure of e.Coli iscs (see paper)
28% identity, 34% coverage: 78:219/416 of query aligns to 62:204/394 of 3lvmB
Sites not aligning to the query:
5b7uA Apo structure of cysteine desulfurase from thermococcus onnurineus na1 at 1.89a (see paper)
21% identity, 81% coverage: 19:356/416 of query aligns to 12:347/402 of 5b7uA
Sites not aligning to the query:
5b87A Crystal structure of a cysteine desulfurase from thermococcus onnurineus na1 in complex with alanine at 2.3 angstrom resolution (see paper)
21% identity, 81% coverage: 19:356/416 of query aligns to 6:341/397 of 5b87A
Sites not aligning to the query:
5wt4A L-cysteine-plp intermediate of nifs from helicobacter pylori (see paper)
29% identity, 18% coverage: 154:228/416 of query aligns to 132:206/358 of 5wt4A
Sites not aligning to the query:
>AO353_05935 FitnessBrowser__pseudo3_N2E3:AO353_05935
MITRNDCLALDAQDPLAHLRHQFALPEGVIYLDGNSLGARPVAALERAQAVIAEEWGNGL
IRSWNSAGWRDLPERLGNRLAGLIGAGEGEVVVTDTTSINLFKVLGAALRVQAMRAPTRR
VIVSESSNFPTDLYIAEGLMDLLQQGYSLRLVDSPEELAQAIDQDTAVVMLTHVNYKTGY
MHDMQAVTALIHECGALAIWDLAHSAGAVPVDLRQAGADYAIGCTYKYLNGGPGSQAFVW
VAPQLCDLVTQPLSGWFGHSRQFDMASGYEPSSGIARYLCGTQPITSLAMVECGLEIFAQ
TDMPSLRRKSLALTDLFIQLVEQRCAAHDLKLITPREHARRGSHVSFEHPQGYAVIQALI
AQGVIGDYREPRIMRFGFTPLYTSFTEVFDAVQILGEILDQQTWSQAQFQVRHSVT
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory