SitesBLAST – Find functional sites

 

SitesBLAST

Comparing AO356_00470 FitnessBrowser__pseudo5_N2C3_1:AO356_00470 to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 2 hits to proteins with known functional sites (download)

4ymtC Crystal structure of an amino acid abc transporter complex with arginines (see paper)
31% identity, 90% coverage: 20:216/220 of query aligns to 17:213/215 of 4ymtC

query
sites
4ymtC
A
 
S
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G
F
 
L
L
 
I
T
 
M
S
 
T
V
 
L
Q
 
K
C
 
L
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T
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F
L
 
L
A
 
A
I
 
V
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I
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G
T
 
V
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L
I
 
M
G
 
G
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L
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F
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I
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A
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L
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M
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K
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M
Y
 
S
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S
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I
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K
W
 
P
M
 
I
R
 
K
A
 
L
P
 
V
F
 
A
R
 
S
F
 
S
Y
 
Y
V
 
I
D
 
E
L
 
V
I
 
I
R
 
R
G
 
G
T
 
T
P
|
P
V
x
L
F
 
L
V
 
V
L
 
Q
V
 
L
L
 
L
A
 
L
C
 
I
F
 
Y
Y
 
N
M
 
G
A
 
L
P
 
M
A
 
Q
L
 
F
G
 
G
W
 
M
Q
 
N
I
 
I
G
 
P
A
 
A
F
 
F
Q
 
T
A
 
A
G
 
G
V
 
V
L
 
S
G
 
A
L
 
L
T
 
A
L
 
I
F
x
N
C
 
S
G
 
S
S
 
A
H
x
Y
V
 
V
A
 
A
E
 
E
I
 
I
V
 
I
R
 
R
G
 
A
A
 
G
L
 
I
Q
 
Q
A
 
A
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V
P
 
D
R
 
P
G
 
G
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Q
M
 
N
E
 
E
A
 
A
S
 
A
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R
A
 
S
I
 
L
G
 
G
L
 
M
T
 
T
F
 
H
Y
 
A
Q
 
M
S
 
A
L
 
M
G
 
R
Y
 
Y
V
 
V
L
 
I
L
 
I
P
 
P
Q
 
Q
A
 
A
L
 
I
R
 
K
Q
 
N
I
 
I
L
 
L
P
 
P
T
 
A
W
 
L
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G
N
 
N
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x
E
S
 
F
T
 
I
E
 
V
I
x
M
V
 
L
K
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K
A
x
E
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A
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A
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D
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D
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I
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T
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Y
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R
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Y
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F
E
 
E
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P
Y
 
Y
L
 
I
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I
A
 
I
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A
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A
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Y
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F
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K
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L
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L
R
 
S
H
 
L
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F
E
 
E
K
 
R
R
 
R

4ymwC Crystal structure of an amino acid abc transporter with histidines (see paper)
31% identity, 90% coverage: 20:216/220 of query aligns to 17:213/214 of 4ymwC

query
sites
4ymwC
A
 
S
G
 
G
F
 
L
L
 
I
T
 
M
S
 
T
V
 
L
Q
 
K
C
 
L
S
 
T
L
 
F
L
 
L
A
 
A
I
 
V
V
 
T
L
 
I
G
 
G
T
 
V
L
 
L
I
 
M
G
 
G
L
 
L
V
 
F
A
 
I
G
 
A
L
 
L
V
 
M
L
 
K
T
 
M
Y
 
S
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S
R
 
I
T
 
K
W
 
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I
R
 
K
A
 
L
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A
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Y
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E
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R
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G
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T
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V
L
 
Q
V
 
L
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L
A
 
L
C
 
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Y
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N
M
 
G
A
 
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M
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F
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I
 
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A
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T
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A
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A
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E
I
 
I
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A
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A
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A
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I
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A
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I
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I
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A
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A
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I
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Y
F
 
F
I
 
V
I
 
M
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T
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L
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F
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S
L
 
K
L
 
L
G
 
L
R
 
S
H
 
L
I
 
F
E
 
E
K
 
R
R
 
R

Query Sequence

>AO356_00470 FitnessBrowser__pseudo5_N2C3_1:AO356_00470
MYESPSWLHELWVARDTLWAGFLTSVQCSLLAIVLGTLIGLVAGLVLTYGRTWMRAPFRF
YVDLIRGTPVFVLVLACFYMAPALGWQIGAFQAGVLGLTLFCGSHVAEIVRGALQALPRG
QMEASQAIGLTFYQSLGYVLLPQALRQILPTWVNSSTEIVKASTLLSVIGVAELLLSTQQ
IIARTFMTLEFYLFAGFLFFIINYAIELLGRHIEKRVALP

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory