Comparing AO356_03465 FitnessBrowser__pseudo5_N2C3_1:AO356_03465 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 18 hits to proteins with known functional sites (download)
P0A9J8 Bifunctional chorismate mutase/prephenate dehydratase; Chorismate mutase-prephenate dehydratase; P-protein; EC 5.4.99.5; EC 4.2.1.51 from Escherichia coli (strain K12)
31% identity, 99% coverage: 2:360/364 of query aligns to 3:376/386 of P0A9J8
3mwbA The crystal structure of prephenate dehydratase in complex with l-phe from arthrobacter aurescens to 2.0a
37% identity, 73% coverage: 98:362/364 of query aligns to 5:277/306 of 3mwbA
2qmxA The crystal structure of l-phe inhibited prephenate dehydratase from chlorobium tepidum tls (see paper)
34% identity, 73% coverage: 96:359/364 of query aligns to 4:273/278 of 2qmxA
3mwbB The crystal structure of prephenate dehydratase in complex with l-phe from arthrobacter aurescens to 2.0a
37% identity, 73% coverage: 98:362/364 of query aligns to 5:274/303 of 3mwbB
6vh5D Crystal structure of prephenate dehydratase from brucella melitensis biovar abortus 2308 in complex with phenylalanine
28% identity, 73% coverage: 95:359/364 of query aligns to 8:276/282 of 6vh5D
7am0B Gqqa- a novel type of quorum quenching acylases (see paper)
26% identity, 73% coverage: 96:362/364 of query aligns to 4:272/278 of 7am0B
3luyA Putative chorismate mutase from bifidobacterium adolescentis
25% identity, 73% coverage: 95:361/364 of query aligns to 5:285/326 of 3luyA
P39912 Protein AroA(G); EC 2.5.1.54; EC 5.4.99.5 from Bacillus subtilis (strain 168) (see paper)
33% identity, 25% coverage: 1:92/364 of query aligns to 1:87/358 of P39912
5j6fA Crystal structure of dah7ps-cm complex from geobacillus sp. With prephenate (see paper)
33% identity, 24% coverage: 4:92/364 of query aligns to 2:85/352 of 5j6fA
Sites not aligning to the query:
3tfcA 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e in complex with phosphoenolpyruvate (see paper)
32% identity, 23% coverage: 9:92/364 of query aligns to 1:74/343 of 3tfcA
Sites not aligning to the query:
5gmuB Crystal structure of chorismate mutase like domain of bifunctional dahp synthase of bacillus subtilis in complex with chlorogenic acid (see paper)
32% identity, 25% coverage: 2:92/364 of query aligns to 1:86/87 of 5gmuB
3nvtA 1.95 angstrom crystal structure of a bifunctional 3-deoxy-7- phosphoheptulonate synthase/chorismate mutase (aroa) from listeria monocytogenes egd-e (see paper)
32% identity, 23% coverage: 9:92/364 of query aligns to 2:75/345 of 3nvtA
Sites not aligning to the query:
7alzA Gqqa- a novel type of quorum quenching acylases (see paper)
28% identity, 32% coverage: 248:362/364 of query aligns to 72:188/194 of 7alzA
P04176 Phenylalanine-4-hydroxylase; PAH; Phe-4-monooxygenase; EC 1.14.16.1 from Rattus norvegicus (Rat) (see 2 papers)
34% identity, 18% coverage: 283:349/364 of query aligns to 36:101/453 of P04176
Sites not aligning to the query:
5fgjA Structure of tetrameric rat phenylalanine hydroxylase, residues 1-453 (see paper)
34% identity, 18% coverage: 283:349/364 of query aligns to 17:82/428 of 5fgjA
Sites not aligning to the query:
P16331 Phenylalanine-4-hydroxylase; PAH; Phe-4-monooxygenase; EC 1.14.16.1 from Mus musculus (Mouse) (see paper)
34% identity, 18% coverage: 283:349/364 of query aligns to 36:101/453 of P16331
Sites not aligning to the query:
6al9B Crystal structure of chorismate mutase from helicobacter pylori in complex with prephenate
33% identity, 21% coverage: 6:83/364 of query aligns to 5:75/91 of 6al9B
Sites not aligning to the query:
6al9A Crystal structure of chorismate mutase from helicobacter pylori in complex with prephenate
33% identity, 21% coverage: 6:83/364 of query aligns to 4:74/90 of 6al9A
Sites not aligning to the query:
>AO356_03465 FitnessBrowser__pseudo5_N2C3_1:AO356_03465
MSEQELKALRLRIDALDEKVLELISERARCAQEVARVKMASLAEGEVPVFYRPEREAQVL
KRVMERNKGPLGNEEMARLFREIMSSCLALEQPLKVAYLGPEGTFTQAAAMKHFGHAVIS
KPMAAIDEVFREVAAGAVNFGVVPVENSTEGAVNHTLDSFLEHDMVICGEVELRIHHHLL
VGENTKTDSISRIYSHAQSLAQCRKWLDAHYPNVERVAVSSNAEAAKRVKGEWNSAAIAG
DMAAGLYGLTRLAEKIEDRPDNSTRFLMIGSQEVPPTGDDKTSIIVSMSNKPGALHELLV
PFHDNGIDLTRIETRPSRSGKWTYVFFIDFVGHHRDPLVKGVLEKISQEAVALKVLGSYP
KAVL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory