Comparing AO356_14360 FitnessBrowser__pseudo5_N2C3_1:AO356_14360 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
Q88QT2 N-acetylmuramate alpha-1-phosphate uridylyltransferase; MurNAc-1P uridylyltransferase; MurNAc-alpha-1P uridylyltransferase; EC 2.7.7.99 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
76% identity, 98% coverage: 1:219/223 of query aligns to 1:219/223 of Q88QT2
4y7uA Structural analysis of muru (see paper)
76% identity, 98% coverage: 1:219/223 of query aligns to 1:219/224 of 4y7uA
4y7vA Structural analysis of muru (see paper)
75% identity, 98% coverage: 1:219/223 of query aligns to 1:214/216 of 4y7vA
7d73E Cryo-em structure of gmppa/gmppb complex bound to gtp (state i) (see paper)
30% identity, 93% coverage: 1:207/223 of query aligns to 1:220/360 of 7d73E
7d72K Cryo-em structures of human gmppa/gmppb complex bound to gdp-mannose (see paper)
30% identity, 93% coverage: 1:207/223 of query aligns to 1:220/360 of 7d72K
7d72E Cryo-em structures of human gmppa/gmppb complex bound to gdp-mannose (see paper)
30% identity, 93% coverage: 1:207/223 of query aligns to 1:220/360 of 7d72E
P74285 UTP--glucose-1-phosphate uridylyltransferase; Cyanobacterial UDP-glucose pyrophosphorylase; UDP-glucose pyrophosphorylase; UDP-Glc PPase; EC 2.7.7.9 from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
31% identity, 93% coverage: 1:207/223 of query aligns to 1:233/388 of P74285
7whsA Cryo-em structure of leishmanial gdp-mannose pyrophosphorylase in complex with gtp (see paper)
28% identity, 93% coverage: 1:207/223 of query aligns to 1:220/366 of 7whsA
7whtA Cryo-em structure of leishmanial gdp-mannose pyrophosphorylase in complex with gdp-mannose (see paper)
29% identity, 93% coverage: 1:207/223 of query aligns to 1:213/360 of 7whtA
7d73B Cryo-em structure of gmppa/gmppb complex bound to gtp (state i) (see paper)
33% identity, 61% coverage: 1:136/223 of query aligns to 2:162/406 of 7d73B
Sites not aligning to the query:
7d72A Cryo-em structures of human gmppa/gmppb complex bound to gdp-mannose (see paper)
33% identity, 61% coverage: 1:136/223 of query aligns to 2:162/407 of 7d72A
Sites not aligning to the query:
O22287 Mannose-1-phosphate guanylyltransferase 1; GDP-mannose pyrophosphorylase 1; Protein CYTOKINESIS DEFECTIVE 1; Protein EMBRYO DEFECTIVE 101; Protein HYPERSENSITIVE TO AMMONIUM ION 1; Protein SENSITIVE TO OZONE 1; Protein VITAMIN C DEFECTIVE 1; EC 2.7.7.13 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
28% identity, 93% coverage: 1:207/223 of query aligns to 1:221/361 of O22287
Sites not aligning to the query:
7x8kB Arabidopsis gdp-d-mannose pyrophosphorylase (vtc1) structure (product- bound) (see paper)
28% identity, 93% coverage: 1:207/223 of query aligns to 1:221/367 of 7x8kB
7x8kA Arabidopsis gdp-d-mannose pyrophosphorylase (vtc1) structure (product- bound) (see paper)
28% identity, 93% coverage: 1:207/223 of query aligns to 1:220/365 of 7x8kA
3hl3A 2.76 angstrom crystal structure of a putative glucose-1-phosphate thymidylyltransferase from bacillus anthracis in complex with a sucrose.
27% identity, 98% coverage: 1:218/223 of query aligns to 2:233/246 of 3hl3A
4ecmA 2.3 angstrom crystal structure of a glucose-1-phosphate thymidylyltransferase from bacillus anthracis in complex with thymidine-5-diphospho-alpha-d-glucose and pyrophosphate (see paper)
27% identity, 98% coverage: 1:218/223 of query aligns to 3:234/245 of 4ecmA
4arwA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor (see paper)
25% identity, 98% coverage: 2:219/223 of query aligns to 5:240/294 of 4arwA
Sites not aligning to the query:
4b5bA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor (see paper)
25% identity, 98% coverage: 2:219/223 of query aligns to 4:239/293 of 4b5bA
Sites not aligning to the query:
4b4gA Pseudomonas aeruginosa rmla in complex with allosteric inhibitor (see paper)
25% identity, 98% coverage: 2:219/223 of query aligns to 4:239/293 of 4b4gA
Sites not aligning to the query:
4b42A Pseudomonas aeruginosa rmla in complex with allosteric inhibitor (see paper)
25% identity, 98% coverage: 2:219/223 of query aligns to 4:239/293 of 4b42A
Sites not aligning to the query:
>AO356_14360 FitnessBrowser__pseudo5_N2C3_1:AO356_14360
MKAMILAAGKGERMRPLTLTTPKPLIRVGGVPLIEYHLRALAKAGFSEIVINHAWLGQQI
EDHLGDGSGFGVSIRFSPEGEPLETGGGIFRALPLLGDDAFVVVNGDIWTDYDFSVLRRP
LKGLAHLVLVDNPEHHPDGDFILADGKVHDGQTPADNLTYSGIAVLHPRLFDGCTGGAFK
LAPLLRTAMAEGCVSGEHLKGHWVDVGTHERLAQVETLIEASG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory