Comparing AO356_16825 FitnessBrowser__pseudo5_N2C3_1:AO356_16825 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 8 hits to proteins with known functional sites (download)
Q88E47 Homogentisate 1,2-dioxygenase; HGDO; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase; EC 1.13.11.5 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
83% identity, 100% coverage: 1:434/434 of query aligns to 1:433/433 of Q88E47
3zdsF Structure of homogentisate 1,2-dioxygenase in complex with reaction intermediates of homogentisate with oxygen. (see paper)
84% identity, 98% coverage: 9:434/434 of query aligns to 1:426/426 of 3zdsF
3zdsC Structure of homogentisate 1,2-dioxygenase in complex with reaction intermediates of homogentisate with oxygen. (see paper)
84% identity, 98% coverage: 9:434/434 of query aligns to 1:426/426 of 3zdsC
4aq6D Substrate bound homogentisate 1,2-dioxygenase (see paper)
84% identity, 98% coverage: 9:434/434 of query aligns to 2:427/427 of 4aq6D
3zdsA Structure of homogentisate 1,2-dioxygenase in complex with reaction intermediates of homogentisate with oxygen. (see paper)
84% identity, 98% coverage: 10:434/434 of query aligns to 1:425/425 of 3zdsA
Q93099 Homogentisate 1,2-dioxygenase; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase; EC 1.13.11.5 from Homo sapiens (Human) (see 13 papers)
49% identity, 99% coverage: 7:434/434 of query aligns to 1:439/445 of Q93099
Q9Y041 Homogentisate 1,2-dioxygenase; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase; EC 1.13.11.5 from Caenorhabditis elegans (see paper)
49% identity, 98% coverage: 5:429/434 of query aligns to 2:433/437 of Q9Y041
1ey2A Human homogentisate dioxygenase with fe(ii) (see paper)
48% identity, 95% coverage: 8:418/434 of query aligns to 1:413/419 of 1ey2A
>AO356_16825 FitnessBrowser__pseudo5_N2C3_1:AO356_16825
MNLDSTMSDLAYQSGLGNEFASEALPGALPIGQNSPQKAPYGLYAELFSGTAFTMARSEA
RRTWMYRIRPSANHPAFTRLERQLAGGPLGEVTPNRLRWNPLDIPAEPTDFLDGLVCMAA
NAGADKPAGVSLYHYRANRSMERVFFNADGEWLIVPQLGRLRIATELGVLELAPLEIAVL
PRGLKFRVELLDPQARGYLAENHGAPLRLPDLGPIGSNGLANPRDFLTPVARYENLAQPT
TLVQKFLGELWGCELDHSPLDVVAWHGNNVPYKYDLRRFNTIGTVSFDHPDPSIFTVLTS
PTSVHGLANLDFVIFPPRWMVAENTFRPPWFHRNLMNEFMGLIQGAYDAKAEGFLPGGTS
LHSCMSAHGPDGETCTKAINADLQPAKIDNTMAFMFETSQVLRPSRFALDCPQLQTDYDA
CWASLPVTFDPTRR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory