Comparing AO356_19910 FitnessBrowser__pseudo5_N2C3_1:AO356_19910 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 20 (the maximum) hits to proteins with known functional sites (download)
4l0oH Structure determination of cystathionine gamma-synthase from helicobacter pylori
35% identity, 96% coverage: 1:365/381 of query aligns to 1:370/373 of 4l0oH
7mcyH Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound nl3 (see paper)
34% identity, 91% coverage: 22:368/381 of query aligns to 23:380/380 of 7mcyH
Sites not aligning to the query:
7mcuH Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound nl2 (see paper)
34% identity, 91% coverage: 22:368/381 of query aligns to 23:380/380 of 7mcuH
Sites not aligning to the query:
7mctH Crystal structure of staphylococcus aureus cystathionine gamma lyase, holoenzyme with bound nl1 (see paper)
34% identity, 91% coverage: 22:368/381 of query aligns to 23:380/380 of 7mctH
Sites not aligning to the query:
7mcqA Crystal structure of staphylococcus aureus cystathionine gamma lyase, aoaa-bound enzyme in dimeric form (see paper)
34% identity, 91% coverage: 22:368/381 of query aligns to 23:380/380 of 7mcqA
7mcbH Crystal structure of staphylococcus aureus cystathionine gamma lyase holoenzyme (see paper)
34% identity, 91% coverage: 22:368/381 of query aligns to 23:380/380 of 7mcbH
Sites not aligning to the query:
5x2xA Crystal structure of pseudomonas putida methionine gamma-lyase wild type with l-homocysteine intermediates (see paper)
34% identity, 95% coverage: 4:366/381 of query aligns to 5:389/392 of 5x2xA
5x2wA Crystal structure of pseudomonas putida methionine gamma-lyase wild type with l-methionine intermediates (see paper)
34% identity, 95% coverage: 4:366/381 of query aligns to 5:389/392 of 5x2wA
1pg8A Crystal structure of l-methionine alpha-, gamma-lyase
34% identity, 95% coverage: 4:366/381 of query aligns to 11:395/398 of 1pg8A
P13254 L-methionine gamma-lyase; MGL; Homocysteine desulfhydrase; L-methioninase; EC 4.4.1.11; EC 4.4.1.2 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
34% identity, 95% coverage: 4:366/381 of query aligns to 11:395/398 of P13254
7d7oB Crystal structure of cystathionine gamma-lyase from bacillus cereus atcc 14579 (see paper)
33% identity, 96% coverage: 1:365/381 of query aligns to 1:376/377 of 7d7oB
3vk3A Crystal structure of l-methionine gamma-lyase from pseudomonas putida c116h mutant complexed with l-methionine (see paper)
34% identity, 95% coverage: 4:366/381 of query aligns to 10:394/397 of 3vk3A
5x30C Crystal structure of pseudomonas putida methionine gamma-lyase c116h mutant with l-homocysteine intermediates. (see paper)
34% identity, 95% coverage: 4:366/381 of query aligns to 6:390/393 of 5x30C
5dx5A Crystal structure of methionine gamma-lyase from clostridium sporogenes (see paper)
35% identity, 96% coverage: 1:366/381 of query aligns to 6:395/399 of 5dx5A
4iyoB Crystal structure of cystathionine gamma lyase from xanthomonas oryzae pv. Oryzae (xometc) in complex with e-site serine, a-site serine, a- site external aldimine structure with aminoacrylate and a-site iminopropionate intermediates (see paper)
36% identity, 90% coverage: 23:365/381 of query aligns to 25:380/381 of 4iyoB
4iy7B Crystal structure of cystathionine gamma lyase (xometc) from xanthomonas oryzae pv. Oryzae in complex with e-site serine, a-site external aldimine structure with serine and a-site external aldimine structure with aminoacrylate intermediates (see paper)
36% identity, 90% coverage: 23:365/381 of query aligns to 25:380/381 of 4iy7B
4iy7A Crystal structure of cystathionine gamma lyase (xometc) from xanthomonas oryzae pv. Oryzae in complex with e-site serine, a-site external aldimine structure with serine and a-site external aldimine structure with aminoacrylate intermediates (see paper)
36% identity, 90% coverage: 23:365/381 of query aligns to 25:380/381 of 4iy7A
4ixzA Native structure of cystathionine gamma lyase (xometc) from xanthomonas oryzae pv. Oryzae at ph 9.0 (see paper)
36% identity, 90% coverage: 23:365/381 of query aligns to 25:380/381 of 4ixzA
4iyoD Crystal structure of cystathionine gamma lyase from xanthomonas oryzae pv. Oryzae (xometc) in complex with e-site serine, a-site serine, a- site external aldimine structure with aminoacrylate and a-site iminopropionate intermediates (see paper)
36% identity, 90% coverage: 23:365/381 of query aligns to 25:380/384 of 4iyoD
8j6nA Crystal structure of cystathionine gamma-lyase in complex with compound 1 (see paper)
34% identity, 95% coverage: 4:366/381 of query aligns to 10:386/390 of 8j6nA
>AO356_19910 FitnessBrowser__pseudo5_N2C3_1:AO356_19910
MKVSTEILHIKVDDRDAHPSVTPIYQCSAFNADSAFFYSRKANPNVTELEQVVASLEGSE
HALAYSTGMSAIYMVLELLKPGASLVINKYIYGCSYKLFQRYAARIGAHLTILDLTTAEG
LKALPANVDMVIFETPTNPFLKDIDIHAVSRAVKQHNPQALVVVDNTWATPIFQKPLNFG
ADISLYSATKYFSGHSDVMGGLVLVNNETIYNRLLEGRFYSGTILTPNSAWLLRRSMQTF
NLRMEKHSQTTASMLNYLRELPFIEHVYYPRIDGRQLSGYGGIVFVDIRPDLVPFYKTFT
SALKWFGTGTGMACVTSMVAQPFSGSHASMTDQEKADMGIEKGLVRLCFGLEDIEDLKED
LLQAFETMESKVDQKSSLDPA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory