SitesBLAST

Q0QLF3 Nicotinate dehydrogenase small FeS subunit; NDH; Nicotinic acid hydroxylase small FeS subunit; NAH; EC 1.17.1.5 from Eubacterium barkeri (Clostridium barkeri) (see paper)
38% identity, 94% coverage: 2:147/156 of query aligns to 6:151/157 of Q0QLF3

query
sites
Q0QLF3

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C42 (= C38) binding [2Fe-2S] cluster
C47 (= C43) binding [2Fe-2S] cluster
C50 (= C46) binding [2Fe-2S] cluster
C62 (= C58) binding [2Fe-2S] cluster
C101 (= C97) binding [2Fe-2S] cluster
C104 (= C100) binding [2Fe-2S] cluster
C136 (= C132) binding [2Fe-2S] cluster
C138 (= C134) binding [2Fe-2S] cluster

1sb3C Structure of 4-hydroxybenzoyl-coa reductase from thauera aromatica (see paper)
38% identity, 95% coverage: 1:148/156 of query aligns to 4:151/161 of 1sb3C

query
sites
1sb3C

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binding fe2/s2 (inorganic) cluster: Q39 (≠ F36), C41 (= C38), G44 (= G41), C46 (= C43), G47 (= G44), C49 (= C46), C61 (= C58), C100 (= C97), G101 (= G98), C103 (= C100), C135 (= C132), C137 (= C134)
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): Q99 (= Q96), C137 (= C134)

1ffuD Carbon monoxide dehydrogenase from hydrogenophaga pseudoflava which lacks the mo-pyranopterin moiety of the molybdenum cofactor (see paper)
35% identity, 98% coverage: 1:153/156 of query aligns to 4:156/156 of 1ffuD

query
sites
1ffuD

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binding fe2/s2 (inorganic) cluster: C41 (= C38), S44 (≠ G41), H45 (≠ L42), C46 (= C43), G47 (= G44), C49 (= C46), C61 (= C58), C100 (= C97), G101 (= G98), C103 (= C100), C135 (= C132), C137 (= C134)

1ffvA Carbon monoxide dehydrogenase from hydrogenophaga pseudoflava (see paper)
35% identity, 98% coverage: 1:153/156 of query aligns to 3:155/155 of 1ffvA

query
sites
1ffvA

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binding fe2/s2 (inorganic) cluster: I38 (≠ F36), C40 (= C38), S43 (≠ G41), C45 (= C43), G46 (= G44), C48 (= C46), C60 (= C58), C99 (= C97), G100 (= G98), C102 (= C100), C134 (= C132), C136 (= C134)
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): Q98 (= Q96), C136 (= C134)

P77165 Aldehyde oxidoreductase iron-sulfur-binding subunit PaoA; EC 1.2.99.6 from Escherichia coli (strain K12) (see paper)
37% identity, 97% coverage: 2:152/156 of query aligns to 63:228/229 of P77165

query
sites
P77165

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C99 (= C38) binding [2Fe-2S] cluster
C104 (= C43) binding [2Fe-2S] cluster
G105 (= G44) binding [2Fe-2S] cluster
C107 (= C46) binding [2Fe-2S] cluster
C119 (= C58) binding [2Fe-2S] cluster
C158 (= C97) binding [2Fe-2S] cluster
C161 (= C100) binding [2Fe-2S] cluster
C208 (= C132) binding [2Fe-2S] cluster
C210 (= C134) binding [2Fe-2S] cluster

5g5gA Escherichia coli periplasmic aldehyde oxidase (see paper)
38% identity, 94% coverage: 2:148/156 of query aligns to 12:173/175 of 5g5gA

query
sites
5g5gA

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binding fe2/s2 (inorganic) cluster: G47 (= G37), C48 (= C38), D49 (≠ G39), G51 (= G41), C53 (= C43), G54 (= G44), C56 (= C46), C68 (= C58), C107 (= C97), G108 (= G98), C110 (= C100), C157 (= C132), C159 (= C134)

1dgjA Crystal structure of the aldehyde oxidoreductase from desulfovibrio desulfuricans atcc 27774 (see paper)
37% identity, 98% coverage: 3:155/156 of query aligns to 5:160/906 of 1dgjA

query
sites
1dgjA

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binding fe2/s2 (inorganic) cluster: V38 (≠ F36), G39 (= G37), C40 (= C38), G41 (= G39), G43 (= G41), Q44 (≠ L42), C45 (= C43), G46 (= G44), C48 (= C46), R58 (= R56), C60 (= C58), C100 (= C97), G101 (= G98), C103 (= C100), C137 (= C132), C139 (= C134)
binding pterin cytosine dinucleotide: Q99 (= Q96), C139 (= C134)

Sites not aligning to the query:

active site: 391, 427, 503, 507, 535, 869, 870
binding molybdenum (iv)oxide: 424, 535, 698, 869
binding pterin cytosine dinucleotide: 423, 424, 535, 652, 655, 656, 657, 658, 697, 698, 700, 702, 703, 799, 800, 803, 804, 807, 865, 866, 867, 868, 869

P19921 Carbon monoxide dehydrogenase small chain; CO dehydrogenase subunit S; CO-DH S; EC 1.2.5.3 from Afipia carboxidovorans (strain ATCC 49405 / DSM 1227 / KCTC 32145 / OM5) (Oligotropha carboxidovorans) (see 2 papers)
34% identity, 97% coverage: 2:152/156 of query aligns to 6:157/166 of P19921

query
sites
P19921

I

I

T

E

L

L

K

T

L

I

N

N

G

G

K

H

D

P

H

V

Q

E

L

A

D

L

V

V

T

E

E

P

D

R

M

T

P

L

L

L

L

I

W

H

A

F

I

I

R

R

D

E

V

Q

A

Q

G

N

Y

L

N

T

G

G

T

A

K

H

F

I

G

G

C
|
C

G

D

L

T

G

S

L

H

C
|
C

G

G

A

A

C
|
C

T

T

I

V

H

D

I

L

D

D

G

G

A

M

P

S

A

V

R

K

S

S

C
|
C

I

T

T

M

P

F

I

A

G

V

S

Q

V

A

K

N

G

G

Q

A

D

S

V

I

S

T

T

T

I

I

D

E

G

G

L

M

H

-

A

A

D

A

P

P

V

D

G

G

Q

T

I

L

-

S

-

A

V

L

Q

Q

K

E

A

G

W

F

L

R

D

M

T

M

A

H

V

G

A

L

Q

Q

C
|
C

G

G

Y

Y

C
|
C

Q

T

G

P

G

G

Q

M

I

I

M

M

S

R

A

S

T

H

A

R

L

L

K

Q

T

E

N

N

P

P

N

S

P

P

S

T

D

E

E

A

Q

E

I

I

E

R

E

F

A

G

M

I

V

G

G

G

N

N

I

L

C
|
C

R

R

C
|
C

G

T

T

G

Y

Y

N

Q

R

N

I

I

K

V

T

K

A

A

I

I

R

Q

Q

Y

A

A

S

A

T

A

H

K

L

I

K

N

C42 (= C38) binding [2Fe-2S] cluster
C47 (= C43) binding [2Fe-2S] cluster
C50 (= C46) binding [2Fe-2S] cluster
C62 (= C58) binding [2Fe-2S] cluster
C102 (= C97) binding [2Fe-2S] cluster
C105 (= C100) binding [2Fe-2S] cluster
C137 (= C132) binding [2Fe-2S] cluster
C139 (= C134) binding [2Fe-2S] cluster

1n5wA Crystal structure of the cu,mo-co dehydrogenase (codh); oxidized form (see paper)
34% identity, 97% coverage: 2:152/156 of query aligns to 4:155/161 of 1n5wA

query
sites
1n5wA

I

I

T

E

L

L

K

T

L

I

N

N

G

G

K

H

D

P

H

V

Q

E

L

A

D

L

V

V

T

E

E

P

D

R

M

T

P

L

L

L

L

I

W

H

A

F

I

I

R

R

D

E

V

Q

A

Q

G

N

Y

L

N

T

G

G

T

A

K

H

F
x
I

G
|
G

C
|
C

G

D

L

T

G
x
S

L
x
H

C
|
C

G
|
G

A

A

C
|
C

T

T

I

V

H

D

I

L

D

D

G

G

A

M

P

S

A

V

R

K

S

S

C
|
C

I

T

T

M

P

F

I

A

G

V

S

Q

V

A

K

N

G

G

Q

A

D

S

V

I

S

T

T

T

I

I

D

E

G

G

L

M

H

-

A

A

D

A

P

P

V

D

G

G

Q

T

I

L

-

S

-

A

V

L

Q

Q

K

E

A

G

W

F

L

R

D

M

T

M

A

H

V

G

A

L

Q

Q

C
|
C

G
|
G

Y

Y

C
|
C

Q

T

G

P

G

G

Q

M

I

I

M

M

S

R

A

S

T

H

A

R

L

L

K

Q

T

E

N

N

P

P

N

S

P

P

S

T

D

E

E

A

Q

E

I

I

E

R

E

F

A

G

M

I

V

G

G

G

N

N

I

L

C
|
C

R

R

C
|
C

G

T

T

G

Y

Y

N

Q

R

N

I

I

K

V

T

K

A

A

I

I

R

Q

Q

Y

A

A

S

A

T

A

H

K

L

I

K

N

binding flavin-adenine dinucleotide: S43 (≠ G41), H44 (≠ L42)
binding fe2/s2 (inorganic) cluster: I38 (≠ F36), G39 (= G37), C40 (= C38), S43 (≠ G41), C45 (= C43), G46 (= G44), C48 (= C46), C60 (= C58), C100 (= C97), G101 (= G98), C103 (= C100), C135 (= C132), C137 (= C134)

1n5wD Crystal structure of the cu,mo-co dehydrogenase (codh); oxidized form (see paper)
34% identity, 97% coverage: 2:152/156 of query aligns to 4:155/158 of 1n5wD

query
sites
1n5wD

I

I

T

E

L

L

K

T

L

I

N

N

G

G

K

H

D

P

H

V

Q

E

L

A

D

L

V

V

T

E

E

P

D

R

M

T

P

L

L

L

L

I

W

H

A

F

I

I

R

R

D

E

V

Q

A

Q

G

N

Y

L

N

T

G

G

T

A

K

H

F

I

G

G

C
|
C

G

D

L

T

G
x
S

L
x
H

C
|
C

G
|
G

A

A

C
|
C

T

T

I

V

H

D

I

L

D

D

G

G

A

M

P

S

A

V

R

K

S

S

C
|
C

I

T

T

M

P

F

I

A

G

V

S

Q

V

A

K

N

G

G

Q

A

D

S

V

I

S

T

T

T

I

I

D

E

G

G

L

M

H

-

A

A

D

A

P

P

V

D

G

G

Q

T

I

L

-

S

-

A

V

L

Q

Q

K

E

A

G

W

F

L

R

D

M

T

M

A

H

V

G

A

L

Q
|
Q

C
|
C

G
|
G

Y

Y

C
|
C

Q

T

G

P

G

G

Q

M

I

I

M

M

S

R

A

S

T

H

A

R

L

L

K

Q

T

E

N

N

P

P

N

S

P

P

S

T

D

E

E

A

Q

E

I

I

E

R

E

F

A

G

M

I

V

G

G

G

N

N

I

L

C
|
C

R

R

C
|
C

G

T

T

G

Y

Y

N

Q

R

N

I

I

K

V

T

K

A

A

I

I

R

Q

Q

Y

A

A

S

A

T

A

H

K

L

I

K

N

binding flavin-adenine dinucleotide: S43 (≠ G41), H44 (≠ L42)
binding fe2/s2 (inorganic) cluster: C40 (= C38), S43 (≠ G41), C45 (= C43), G46 (= G44), C48 (= C46), C60 (= C58), C100 (= C97), G101 (= G98), C103 (= C100), C135 (= C132), C137 (= C134)
binding pterin cytosine dinucleotide: Q99 (= Q96), C137 (= C134)

4usaA Aldehyde oxidoreductase from desulfovibrio gigas (mop), soaked with trans-cinnamaldehyde (see paper)
36% identity, 93% coverage: 4:148/156 of query aligns to 6:153/907 of 4usaA

query
sites
4usaA

L

I

K

T

L

V

N

N

G

G

K

I

D

E

H

Q

Q

N

L

L

D

F

V

V

T

D

E

A

D

E

M

A

P

L

L

L

L

S

W

D

A

V

I

L

R

R

D

Q

V

Q

A

L

G

G

Y

L

N

T

G

G

T

V

K

K

F
x
V

G

G

C
|
C

G
x
E

L

Q

G
|
G

L

Q

C
|
C

G
|
G

A

A

C
|
C

T

S

I

V

H

I

I

L

D

D

G

G

A

K

P

V

A

V

R
|
R

S

A

C
|
C

I

V

T

T

P

K

I

M

G

K

S

R

V

V

-

A

K

D

G

G

Q

A

D

Q

V

I

S

T

T

T

I

I

D

E

G

G

L

V

H

G

A

Q

D

P

P

E

V

N

G

L

Q

H

I

P

V

L

Q

Q

K

K

A

A

W

W

L

V

D

L

T

H

A

G

V

G

A

A

Q
|
Q

C
|
C

G
|
G

Y

F

C
|
C

Q

S

G

P

G

G

Q

F

I

I

M

V

S

S

A

A

T

K

A

G

L

L

K

D

T

T

N

N

P

A

N

D

P

P

S

S

D

R

E

E

Q

D

I

V

E

R

E

D

A

W

M

F

V

Q

G

K

-

H

-

R

N

N

I

A

C
|
C

R

R

C
|
C

G

T

T

G

Y

Y

N

K

R

P

I

L

K

V

T

D

A

A

I

V

R

M

Q

D

A

A

S

A

binding fe2/s2 (inorganic) cluster: V38 (≠ F36), C40 (= C38), E41 (≠ G39), G43 (= G41), C45 (= C43), G46 (= G44), C48 (= C46), R58 (= R56), C60 (= C58), C100 (= C97), G101 (= G98), C103 (= C100), C137 (= C132), C139 (= C134)
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): Q99 (= Q96), C139 (= C134)

Sites not aligning to the query:

active site: 390, 425, 501, 505, 533, 869, 870
binding bicarbonate ion: 460, 531, 532, 535, 539
binding hydrocinnamic acid: 255, 425, 494, 497, 535, 626
binding magnesium ion: 899, 903
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): 420, 421, 422, 533, 650, 653, 654, 655, 656, 695, 696, 697, 700, 701, 799, 800, 804, 807, 865, 866, 867, 868, 869

4us9A Aldehyde oxidoreductase from desulfovibrio gigas (mop), soaked with 3- phenylpropionaldehyde (see paper)
36% identity, 93% coverage: 4:148/156 of query aligns to 6:153/907 of 4us9A

query
sites
4us9A

L

I

K

T

L

V

N

N

G

G

K

I

D

E

H

Q

Q

N

L

L

D

F

V

V

T

D

E

A

D

E

M

A

P

L

L

L

L

S

W

D

A

V

I

L

R

R

D

Q

V

Q

A

L

G

G

Y

L

N

T

G

G

T

V

K

K

F
x
V

G

G

C
|
C

G
x
E

L

Q

G
|
G

L

Q

C
|
C

G
|
G

A

A

C
|
C

T

S

I

V

H

I

I

L

D

D

G

G

A

K

P

V

A

V

R
|
R

S

A

C
|
C

I

V

T

T

P

K

I

M

G

K

S

R

V

V

-

A

K

D

G

G

Q

A

D

Q

V

I

S

T

T

T

I

I

D

E

G

G

L

V

H

G

A

Q

D

P

P

E

V

N

G

L

Q

H

I

P

V

L

Q

Q

K

K

A

A

W

W

L

V

D

L

T

H

A

G

V

G

A

A

Q
|
Q

C
|
C

G
|
G

Y

F

C
|
C

Q

S

G

P

G

G

Q

F

I

I

M

V

S

S

A

A

T

K

A

G

L

L

K

D

T

T

N

N

P

A

N

D

P

P

S

S

D

R

E

E

Q

D

I

V

E

R

E

D

A

W

M

F

V

Q

G

K

-

H

-

R

N

N

I

A

C
|
C

R

R

C
|
C

G

T

T

G

Y

Y

N

K

R

P

I

L

K

V

T

D

A

A

I

V

R

M

Q

D

A

A

S

A

binding fe2/s2 (inorganic) cluster: V38 (≠ F36), C40 (= C38), E41 (≠ G39), G43 (= G41), C45 (= C43), G46 (= G44), C48 (= C46), R58 (= R56), C60 (= C58), C100 (= C97), G101 (= G98), C103 (= C100), C137 (= C132), C139 (= C134)
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): Q99 (= Q96), C139 (= C134)

Sites not aligning to the query:

active site: 390, 425, 501, 505, 533, 869, 870
binding 3-phenylpropanal: 255, 257, 258, 752
binding bicarbonate ion: 460, 498, 531, 532, 535, 539, 890, 892
binding magnesium ion: 899, 903
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): 420, 421, 422, 533, 650, 653, 654, 655, 656, 695, 696, 697, 700, 701, 799, 800, 804, 807, 865, 866, 867, 868, 869

4us8A Aldehyde oxidoreductase from desulfovibrio gigas (mop), soaked with benzaldehyde (see paper)
36% identity, 93% coverage: 4:148/156 of query aligns to 6:153/907 of 4us8A

query
sites
4us8A

L

I

K

T

L

V

N

N

G

G

K

I

D

E

H

Q

Q

N

L

L

D

F

V

V

T

D

E

A

D

E

M

A

P

L

L

L

L

S

W

D

A

V

I

L

R

R

D

Q

V

Q

A

L

G

G

Y

L

N

T

G

G

T

V

K

K

F
x
V

G

G

C
|
C

G
x
E

L

Q

G
|
G

L

Q

C
|
C

G
|
G

A

A

C
|
C

T

S

I

V

H

I

I

L

D

D

G

G

A

K

P

V

A

V

R
|
R

S

A

C
|
C

I

V

T

T

P

K

I

M

G

K

S

R

V

V

-

A

K

D

G

G

Q

A

D

Q

V

I

S

T

T

T

I

I

D

E

G

G

L

V

H

G

A

Q

D

P

P

E

V

N

G

L

Q

H

I

P

V

L

Q

Q

K

K

A

A

W

W

L

V

D

L

T

H

A

G

V

G

A

A

Q
|
Q

C
|
C

G
|
G

Y

F

C
|
C

Q

S

G

P

G

G

Q

F

I

I

M

V

S

S

A

A

T

K

A

G

L

L

K

D

T

T

N

N

P

A

N

D

P

P

S

S

D

R

E

E

Q

D

I

V

E

R

E

D

A

W

M

F

V

Q

G

K

-

H

-

R

N

N

I

A

C
|
C

R

R

C
|
C

G

T

T

G

Y

Y

N

K

R

P

I

L

K

V

T

D

A

A

I

V

R

M

Q

D

A

A

S

A

binding fe2/s2 (inorganic) cluster: V38 (≠ F36), C40 (= C38), E41 (≠ G39), G43 (= G41), C45 (= C43), G46 (= G44), C48 (= C46), R58 (= R56), C60 (= C58), C100 (= C97), G101 (= G98), C103 (= C100), C137 (= C132), C139 (= C134)
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): Q99 (= Q96), C139 (= C134)

Sites not aligning to the query:

active site: 390, 425, 501, 505, 533, 869, 870
binding bicarbonate ion: 460, 498, 531, 532, 535, 539
binding benzaldehyde: 255, 255, 394, 425, 425, 425, 425, 497, 497, 501, 531, 535, 535, 626, 626, 626, 694, 696, 697
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): 420, 421, 422, 533, 653, 654, 655, 656, 695, 696, 697, 700, 701, 799, 800, 804, 807, 865, 866, 867, 868, 869

4c7yA Aldehyde oxidoreductase from desulfovibrio gigas (mop), soaked with sodium dithionite and sodium sulfide (see paper)
36% identity, 93% coverage: 4:148/156 of query aligns to 6:153/907 of 4c7yA

query
sites
4c7yA

L

I

K

T

L

V

N

N

G

G

K

I

D

E

H

Q

Q

N

L

L

D

F

V

V

T

D

E

A

D

E

M

A

P

L

L

L

L

S

W

D

A

V

I

L

R

R

D

Q

V

Q

A

L

G

G

Y

L

N

T

G

G

T

V

K

K

F

V

G

G

C
|
C

G
x
E

L

Q

G
|
G

L

Q

C
|
C

G
|
G

A

A

C
|
C

T

S

I

V

H

I

I

L

D

D

G

G

A

K

P

V

A

V

R
|
R

S

A

C
|
C

I

V

T

T

P

K

I

M

G

K

S

R

V

V

-

A

K

D

G

G

Q

A

D

Q

V

I

S

T

T

T

I

I

D

E

G

G

L

V

H

G

A

Q

D

P

P

E

V

N

G

L

Q

H

I

P

V

L

Q

Q

K

K

A

A

W

W

L

V

D

L

T

H

A

G

V

G

A

A

Q
|
Q

C
|
C

G
|
G

Y

F

C
|
C

Q

S

G

P

G

G

Q

F

I

I

M

V

S

S

A

A

T

K

A

G

L

L

K

D

T

T

N

N

P

A

N

D

P

P

S

S

D

R

E

E

Q

D

I

V

E

R

E

D

A

W

M

F

V

Q

G

K

-

H

-

R

N

N

I

A

C
|
C

R

R

C
|
C

G

T

T

G

Y

Y

N

K

R

P

I

L

K

V

T

D

A

A

I

V

R

M

Q

D

A

A

S

A

binding fe2/s2 (inorganic) cluster: C40 (= C38), E41 (≠ G39), G43 (= G41), C45 (= C43), G46 (= G44), C48 (= C46), R58 (= R56), C60 (= C58), C100 (= C97), G101 (= G98), C103 (= C100), C137 (= C132), C139 (= C134)
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): Q99 (= Q96), C139 (= C134)

Sites not aligning to the query:

active site: 390, 425, 501, 505, 533, 869, 870
binding bicarbonate ion: 460, 498, 531, 535, 539
binding magnesium ion: 899, 903
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): 420, 421, 422, 533, 650, 653, 654, 655, 656, 695, 696, 700, 701, 799, 800, 804, 807, 865, 866, 867, 868, 869
binding hydrogen peroxide: 696, 697, 869

3fc4A Ethylene glycol inhibited form of aldehyde oxidoreductase from desulfovibrio gigas (see paper)
36% identity, 93% coverage: 4:148/156 of query aligns to 6:153/907 of 3fc4A

query
sites
3fc4A

L

I

K

T

L

V

N

N

G

G

K

I

D

E

H

Q

Q

N

L

L

D

F

V

V

T

D

E

A

D

E

M

A

P

L

L

L

L

S

W

D

A

V

I

L

R

R

D

Q

V

Q

A

L

G

G

Y

L

N

T

G

G

T

V

K

K

F
x
V

G

G

C
|
C

G
x
E

L

Q

G
|
G

L

Q

C
|
C

G
|
G

A

A

C
|
C

T

S

I

V

H

I

I

L

D

D

G

G

A

K

P

V

A

V

R
|
R

S

A

C
|
C

I

V

T

T

P

K

I

M

G

K

S

R

V

V

-

A

K

D

G

G

Q

A

D

Q

V

I

S

T

T

T

I

I

D

E

G

G

L

V

H

G

A

Q

D

P

P

E

V

N

G

L

Q

H

I

P

V

L

Q

Q

K

K

A

A

W

W

L

V

D

L

T

H

A

G

V

G

A

A

Q
|
Q

C
|
C

G
|
G

Y

F

C
|
C

Q

S

G

P

G

G

Q

F

I

I

M

V

S

S

A

A

T

K

A

G

L

L

K

D

T

T

N

N

P

A

N

D

P

P

S

S

D

R

E

E

Q

D

I

V

E

R

E

D

A

W

M

F

V

Q

G

K

-

H

-

R

N

N

I

A

C
|
C

R

R

C
|
C

G

T

T

G

Y

Y

N

K

R

P

I

L

K

V

T

D

A

A

I

V

R

M

Q

D

A

A

S

A

binding fe2/s2 (inorganic) cluster: V38 (≠ F36), C40 (= C38), E41 (≠ G39), G43 (= G41), C45 (= C43), G46 (= G44), C48 (= C46), R58 (= R56), C60 (= C58), C100 (= C97), G101 (= G98), C103 (= C100), C137 (= C132), C139 (= C134)
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): Q99 (= Q96), C139 (= C134)

Sites not aligning to the query:

active site: 390, 425, 501, 505, 533, 869, 870
binding 1,2-ethanediol: 535, 622, 696, 697, 869
binding magnesium ion: 899, 903
binding (molybdopterin-cytosine dinucleotide-s,s)-dioxo-aqua-molybdenum(v): 419, 420, 421, 422, 533, 650, 653, 654, 655, 656, 695, 696, 700, 701, 799, 800, 804, 807, 865, 866, 867, 868, 869

Query Sequence

>AO356_20100 FitnessBrowser__pseudo5_N2C3_1:AO356_20100
MITLKLNGKDHQLDVTEDMPLLWAIRDVAGYNGTKFGCGLGLCGACTIHIDGAPARSCIT
PIGSVKGQDVSTIDGLHADPVGQIVQKAWLDTAVAQCGYCQGGQIMSATALLKTNPNPSD
EQIEEAMVGNICRCGTYNRIKTAIRQASTHLKEAKA

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory