Comparing AO356_29975 FitnessBrowser__pseudo5_N2C3_1:AO356_29975 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8sutA Crystal structure of yisk from bacillus subtilis in complex with reaction product 4-hydroxy-2-oxoglutaric acid (see paper)
42% identity, 83% coverage: 44:279/283 of query aligns to 54:301/303 of 8sutA
8skyB Crystal structure of yisk from bacillus subtilis in complex with oxalate (see paper)
42% identity, 83% coverage: 44:279/283 of query aligns to 53:300/303 of 8skyB
6j5xB Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
31% identity, 100% coverage: 1:282/283 of query aligns to 1:279/280 of 6j5xB
6j5xA Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
31% identity, 100% coverage: 1:282/283 of query aligns to 1:279/280 of 6j5xA
6iymA Fumarylacetoacetate hydrolase (eafah) from psychrophilic exiguobacterium antarcticum (see paper)
33% identity, 99% coverage: 1:279/283 of query aligns to 2:274/277 of 6iymA
6v77B Crystal structure of a putative hpce protein from mycobacterium smegmatis
34% identity, 98% coverage: 1:277/283 of query aligns to 1:273/279 of 6v77B
8gstC Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Pyruvate bound-form) (see paper)
37% identity, 71% coverage: 74:274/283 of query aligns to 71:273/290 of 8gstC
8gsrA Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Apo-form) (see paper)
37% identity, 71% coverage: 74:274/283 of query aligns to 71:273/290 of 8gsrA
3r6oA Crystal structure of a probable 2-hydroxyhepta-2,4-diene-1, 7- dioateisomerase from mycobacterium abscessus (see paper)
34% identity, 78% coverage: 61:282/283 of query aligns to 50:263/265 of 3r6oA
1gttA Crystal structure of hpce (see paper)
38% identity, 64% coverage: 69:250/283 of query aligns to 217:392/421 of 1gttA
6sbiA X-ray structure of murine fumarylacetoacetate hydrolase domain containing protein 1 (fahd1) in complex with inhibitor oxalate (see paper)
37% identity, 62% coverage: 76:250/283 of query aligns to 14:191/216 of 6sbiA
Q6P587 Acylpyruvase FAHD1, mitochondrial; Fumarylacetoacetate hydrolase domain-containing protein 1; FAH domain-containing protein 1; Oxaloacetate decarboxylase; OAA decarboxylase; YisK-like protein; EC 3.7.1.5; EC 4.1.1.112 from Homo sapiens (Human) (see 3 papers)
38% identity, 62% coverage: 76:250/283 of query aligns to 17:194/221 of Q6P587
6fogA X-ray structure of homo sapiens fumarylacetoacetate hydrolase domain containing protein 1 (fahd1) in complex with inhibitor oxalate at 1.94a resolution. (see paper)
38% identity, 62% coverage: 76:250/283 of query aligns to 15:192/218 of 6fogA
Sites not aligning to the query:
6jvwB Crystal structure of maleylpyruvate hydrolase from sphingobium sp. Syk-6 in complex with manganese (ii) ion and pyruvate (see paper)
30% identity, 95% coverage: 13:280/283 of query aligns to 10:261/264 of 6jvwB
3qdfA Crystal structure of 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase from mycobacterium marinum (see paper)
33% identity, 73% coverage: 75:280/283 of query aligns to 63:248/252 of 3qdfA
4dbhA Crystal structure of cg1458 with inhibitor (see paper)
33% identity, 74% coverage: 73:281/283 of query aligns to 61:268/269 of 4dbhA
6j5yA Crystal structure of fumarylpyruvate hydrolase from pseudomonas aeruginosa in complex with mn2+ and pyruvate (see paper)
34% identity, 62% coverage: 75:250/283 of query aligns to 25:208/233 of 6j5yA
3v77A Crystal structure of a putative fumarylacetoacetate isomerase/hydrolase from oleispira antarctica (see paper)
30% identity, 63% coverage: 74:250/283 of query aligns to 16:197/224 of 3v77A
1nkqA Crystal structure of yeast ynq8, a fumarylacetoacetate hydrolase family protein
24% identity, 67% coverage: 75:263/283 of query aligns to 10:216/247 of 1nkqA
3bqbX Hexagonal kristal form of 2-keto-3-deoxyarabinonate dehydratase (see paper)
29% identity, 63% coverage: 99:275/283 of query aligns to 115:282/291 of 3bqbX
>AO356_29975 FitnessBrowser__pseudo5_N2C3_1:AO356_29975
MKLISYRKEGRAHFGVVSGDGVVELTRRFAQVPDLATFLANRLLVQEARKIVETAQADYS
FSSIQLEAVIPNPGKVICVGINYVAHAEEAGRKVGEFPVIFQRFAETLLPHGEPLVRPKV
SEQFDFEAELAVVIGKGGAHIDPADAMDHVAGYTCFNDASVRDWQFHTHQYGMGKTFRKT
GALGPWIIPASEISDYRTLVVRGILNGEQLQEGSLSELAFDIPHLISYVSKALPWNPGDI
LATGTPSGIGFKRKPPIFLKPGDVFEVVITEIGTLSNGVIDEA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory