Comparing AZOBR_RS07460 FitnessBrowser__azobra:AZOBR_RS07460 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P00903 Aminodeoxychorismate synthase component 2; ADC synthase; ADCS; 4-amino-4-deoxychorismate synthase component 2; Aminodeoxychorismate synthase, glutamine amidotransferase component; EC 2.6.1.85 from Escherichia coli (strain K12) (see paper)
56% identity, 95% coverage: 1:187/196 of query aligns to 1:186/187 of P00903
Q42565 Anthranilate synthase beta subunit 1, chloroplastic; Anthranilate synthase component 2-1; Anthranilate synthase, glutamine amidotransferase component 2-1; Protein TRYPTOPHAN BIOSYNTHESIS 4; Protein WEAK ETHYLENE INSENSITIVE 7; EC 4.1.3.27 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
47% identity, 98% coverage: 2:194/196 of query aligns to 75:272/276 of Q42565
8hx8A Crystal structure of 4-amino-4-deoxychorismate synthase from streptomyces venezuelae co-crystallized with chorismate (see paper)
49% identity, 94% coverage: 3:187/196 of query aligns to 7:189/673 of 8hx8A
Sites not aligning to the query:
P00900 Anthranilate synthase component 2; AS; ASII; Anthranilate synthase, GATase component; Anthranilate synthase, glutamine amidotransferase component; EC 4.1.3.27 from Serratia marcescens (see 3 papers)
38% identity, 94% coverage: 2:186/196 of query aligns to 4:187/193 of P00900
Sites not aligning to the query:
1i7qB Anthranilate synthase from s. Marcescens (see paper)
38% identity, 94% coverage: 2:186/196 of query aligns to 3:186/192 of 1i7qB
8hx9A Crystal structure of 4-amino-4-deoxychorismate synthase from streptomyces venezuelae with chorismate (see paper)
38% identity, 94% coverage: 3:187/196 of query aligns to 6:146/632 of 8hx9A
Sites not aligning to the query:
7yc6A Crystal structure of d110p mutant of gatase subunit of methanocaldococcus jannaschii gmp synthetase
32% identity, 94% coverage: 1:185/196 of query aligns to 1:174/183 of 7yc6A
2ywcA Crystal structure of gmp synthetase from thermus thermophilus in complex with xmp
32% identity, 95% coverage: 1:187/196 of query aligns to 1:182/475 of 2ywcA
Sites not aligning to the query:
Q9LVW7 Carbamoyl phosphate synthase small chain, chloroplastic; Carbamoyl phosphate synthetase glutamine chain; Protein VENOSA 6; EC 6.3.5.5 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
26% identity, 93% coverage: 14:196/196 of query aligns to 254:430/430 of Q9LVW7
1ce8B Carbamoyl phosphate synthetase from escherichis coli with complexed with the allosteric ligand imp (see paper)
29% identity, 73% coverage: 35:177/196 of query aligns to 223:360/379 of 1ce8B
Sites not aligning to the query:
P0A6F1 Carbamoyl phosphate synthase small chain; Carbamoyl phosphate synthetase glutamine chain; EC 6.3.5.5 from Escherichia coli (strain K12) (see paper)
29% identity, 73% coverage: 35:177/196 of query aligns to 224:361/382 of P0A6F1
Sites not aligning to the query:
1c3oB Crystal structure of the carbamoyl phosphate synthetase: small subunit mutant c269s with bound glutamine (see paper)
29% identity, 73% coverage: 35:177/196 of query aligns to 223:360/379 of 1c3oB
Sites not aligning to the query:
Q18990 Multifunctional protein pyr-1; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Caenorhabditis elegans (see 3 papers)
31% identity, 65% coverage: 45:171/196 of query aligns to 219:341/2198 of Q18990
Sites not aligning to the query:
5tw7F Crystal structure of a gmp synthase (glutamine-hydrolyzing) from neisseria gonorrhoeae
27% identity, 79% coverage: 33:186/196 of query aligns to 36:188/490 of 5tw7F
Sites not aligning to the query:
P27708 Multifunctional protein CAD; Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Homo sapiens (Human) (see 7 papers)
29% identity, 82% coverage: 11:171/196 of query aligns to 185:338/2225 of P27708
Sites not aligning to the query:
1gpmA Escherichia coli gmp synthetase complexed with amp and pyrophosphate (see paper)
24% identity, 94% coverage: 2:186/196 of query aligns to 8:196/501 of 1gpmA
Sites not aligning to the query:
P07259 Multifunctional protein URA2; Pyrimidine-specific carbamoyl phosphate synthase-aspartate carbamoyl transferase; CPSase-ATCase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
29% identity, 82% coverage: 13:172/196 of query aligns to 238:389/2214 of P07259
Sites not aligning to the query:
P08955 Multifunctional protein CAD; Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase; EC 6.3.5.5; EC 3.5.1.2; EC 6.3.4.16; EC 2.1.3.2; EC 3.5.2.3 from Mesocricetus auratus (Golden hamster) (see paper)
28% identity, 92% coverage: 11:190/196 of query aligns to 185:358/2225 of P08955
Sites not aligning to the query:
7d50B Spua mutant - h221n with glutamyl-thioester (see paper)
33% identity, 60% coverage: 55:171/196 of query aligns to 93:228/255 of 7d50B
7d53A Spua mutant - h221n with glu (see paper)
33% identity, 60% coverage: 55:171/196 of query aligns to 87:222/249 of 7d53A
Sites not aligning to the query:
>AZOBR_RS07460 FitnessBrowser__azobra:AZOBR_RS07460
MLLLIDNYDSFTYNLVHYLGELGAELDVRRNDSLTVEEAMALRPEGIVLSPGPCDPDKAG
ICLPLIDAAAKAGVPLMGVCLGHQAIGQAFGGTVLRAPVPMHGKVDRMFHQGRGVLKDLP
SPFRATRYHSLIVERATLPACLEVTGETEDGLIMALSHCELPIHGVQFHPESIESEHGHK
ILENFLNTTRRLETAA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory