Comparing AZOBR_RS10395 FitnessBrowser__azobra:AZOBR_RS10395 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 10 hits to proteins with known functional sites (download)
P0A991 Fructose-bisphosphate aldolase class 1; Fructose-bisphosphate aldolase class I; FBP aldolase; EC 4.1.2.13 from Escherichia coli (strain K12) (see 2 papers)
36% identity, 93% coverage: 19:305/309 of query aligns to 47:342/350 of P0A991
Sites not aligning to the query:
P58315 Fructose-bisphosphate aldolase class 1; Fructose-bisphosphate aldolase class I; FBP aldolase; FBPA; EC 4.1.2.13 from Thermoproteus tenax (strain ATCC 35583 / DSM 2078 / JCM 9277 / NBRC 100435 / Kra 1) (see paper)
35% identity, 88% coverage: 38:309/309 of query aligns to 16:256/263 of P58315
2yceE Structure of an archaeal fructose-1,6-bisphosphate aldolase with the catalytic lys covalently bound to the carbinolamine intermediate of the substrate. (see paper)
34% identity, 88% coverage: 38:309/309 of query aligns to 14:254/255 of 2yceE
1w8sA The mechanism of the schiff base forming fructose-1,6-bisphosphate aldolase: structural analysis of reaction intermediates (see paper)
34% identity, 84% coverage: 38:297/309 of query aligns to 14:241/250 of 1w8sA
P58314 Fructose-bisphosphate aldolase class 1; Fructose-bisphosphate aldolase class I; FBP aldolase; EC 4.1.2.13 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (see paper)
30% identity, 86% coverage: 38:302/309 of query aligns to 21:265/281 of P58314
2qjgA M. Jannaschii adh synthase complexed with f1,6p (see paper)
22% identity, 87% coverage: 39:306/309 of query aligns to 26:258/272 of 2qjgA
3gndA Crystal structure of e. Coli lsrf in complex with ribulose-5-phosphate (see paper)
24% identity, 87% coverage: 20:288/309 of query aligns to 26:245/276 of 3gndA
3glcA Crystal structure of e. Coli lsrf in complex with ribose-5-phosphate (see paper)
24% identity, 87% coverage: 20:288/309 of query aligns to 26:245/276 of 3glcA
P76143 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase; EC 2.3.1.245 from Escherichia coli (strain K12) (see paper)
24% identity, 87% coverage: 20:288/309 of query aligns to 35:258/291 of P76143
4p2vA Structure of the ai-2 processing enzyme lsrf in complex with the product of the lsrg reaction p-hpd (see paper)
23% identity, 87% coverage: 20:288/309 of query aligns to 27:250/281 of 4p2vA
>AZOBR_RS10395 FitnessBrowser__azobra:AZOBR_RS10395
MKLTRRVKEILANYESDTPGVKANLARILMEGKLGGTGKLVILPVDQGFEHGPARSFAPN
EPGYDPHYHYQLAIDAGCNAYAAPLGSLEAGASTFAGSIPLILKMNSANSLSRQKEDADQ
AVTASVQDALRLGCSAIGFTIYPGSDAMYDQYEEIRELSKEAKSVGLPTVLWSYPRGGTI
SKEGELAIDVIGYAAHMAALLGAHIIKVKLPSAHLEQAEAKKVYESKNIPIATQADRVRH
IMQCAFNGRRIVVFSGGATKGEDAVFEDARAIRDGGGNGSIIGRNAFQRPREDALKLLDR
IMKIYQGKE
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory