Comparing AZOBR_RS10460 FitnessBrowser__azobra:AZOBR_RS10460 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 10 hits to proteins with known functional sites (download)
1wyvA Crystal structure of glycine decarboxylase (p-protein) of the glycine cleavage system, in inhibitor-bound form (see paper)
46% identity, 100% coverage: 1:446/446 of query aligns to 1:437/437 of 1wyvA
1wyuA Crystal structure of glycine decarboxylase (p-protein) of the glycine cleavage system, in holo form (see paper)
46% identity, 100% coverage: 1:446/446 of query aligns to 1:437/437 of 1wyuA
P15505 Glycine dehydrogenase (decarboxylating), mitochondrial; Glycine cleavage system P protein; Glycine decarboxylase; Glycine dehydrogenase (aminomethyl-transferring); EC 1.4.4.2 from Gallus gallus (Chicken) (see paper)
37% identity, 98% coverage: 2:436/446 of query aligns to 56:466/1004 of P15505
Sites not aligning to the query:
6i33A Crystal structure of human glycine decarboxylase (p-protein)
36% identity, 98% coverage: 2:436/446 of query aligns to 18:434/950 of 6i33A
Sites not aligning to the query:
6i33B Crystal structure of human glycine decarboxylase (p-protein)
36% identity, 98% coverage: 2:436/446 of query aligns to 16:432/925 of 6i33B
Sites not aligning to the query:
6i35A Crystal structure of human glycine decarboxylase (p-protein) bound with pyridoxyl-glycine-5'-monophosphate
36% identity, 98% coverage: 2:436/446 of query aligns to 18:434/953 of 6i35A
Sites not aligning to the query:
6i34B Crystal structure of neanderthal glycine decarboxylase (p-protein)
36% identity, 98% coverage: 2:436/446 of query aligns to 16:432/954 of 6i34B
Sites not aligning to the query:
Q94B78 Glycine dehydrogenase (decarboxylating) 1, mitochondrial; Glycine cleavage system P protein 1; Glycine decarboxylase 1; Glycine decarboxylase P-protein 1; AtGLDP1; Glycine dehydrogenase (aminomethyl-transferring) 1; EC 1.4.4.2 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
34% identity, 87% coverage: 2:387/446 of query aligns to 82:462/1037 of Q94B78
Sites not aligning to the query:
4lhdA Crystal structure of synechocystis sp. Pcc 6803 glycine decarboxylase (p-protein), holo form with pyridoxal-5'-phosphate and glycine, closed flexible loop (see paper)
34% identity, 90% coverage: 2:404/446 of query aligns to 22:416/952 of 4lhdA
Sites not aligning to the query:
1wyuB Crystal structure of glycine decarboxylase (p-protein) of the glycine cleavage system, in holo form (see paper)
25% identity, 78% coverage: 101:446/446 of query aligns to 94:437/473 of 1wyuB
Sites not aligning to the query:
>AZOBR_RS10460 FitnessBrowser__azobra:AZOBR_RS10460
MRYLPLTEADRRSMLEAIGVPSVDELFRDVPEAARLSGPIEGLSNHMGELEVDRALSAMA
GKNLPAGSVPSFLGAGAYRHHIPATVDHLVQRGEFLTAYTPYQPEVSQGTLQVLFEFQTQ
VSLLTGMDVANASMYDGATACAEAVMMANRVTRRKKAVLSGGLHPHYRDTTTTDARFIGF
ETVVMPPAPTGGEDLLAAVDGDTSCVVVQNPDVFGHVRDYTELGKACQAKGALLIVVVTE
AVSLGLLTPPGDMGADIVAAEGQSLGNALNFGGPYVGLFAVKEKLVRQMPGRLCGQTVDA
DGRRGFVLTLSTREQHIRREKATSNICTNSGLCALAFSIHLSLLGEEGFTRLAEINHAKA
VQLADKLAAVTGVEIVNDSFFNEFTVKLPKPAAEVVEALAQRGILGGVPASRLFGGGLDD
LLIVAATETNTESDMDAFATALAEVL
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory