SitesBLAST

Q7WTT9 Arsenate respiratory reductase iron-sulfur subunit ArrB; Arsenate respiratory reductase small subunit; ARR small subunit from Shewanella sp. (strain ANA-3) (see paper)
26% identity, 90% coverage: 3:192/211 of query aligns to 2:234/234 of Q7WTT9

query
sites
Q7WTT9

R

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G

F

M

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I

D

D

A

L

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C

I

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E

G

C
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C

N

G

A

G

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C

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L

A

A

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C

K

K

N

T

E

E

H

N

D

N

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N

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D

G

G

I

I

N

H

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D

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-

Y

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Y

I

I

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L

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C

M

N

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H

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C

N

D

D

D

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C

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N

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C

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Y

K

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C

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Y

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G

A

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G

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-

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M

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L

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K

-

R

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T

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G

-

A

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T

-

A

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T

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P

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N

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Y

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T

-

T

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x
C

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x
C

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N

H

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C

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A

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Y

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I

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Y

C12 (= C13) binding
C15 (= C16) binding
C18 (= C19) binding
C22 (= C23) binding
C57 (= C55) binding
C60 (= C58) binding
C65 (= C63) binding
C69 (= C67) binding
C89 (= C87) binding
C92 (= C90) binding
C95 (= C93) binding
C99 (= C97) binding
C164 (vs. gap) binding
C167 (vs. gap) binding
C179 (= C151) binding
C183 (= C155) binding

6lodB Cryo-em structure of the air-oxidized photosynthetic alternative complex iii from roseiflexus castenholzii (see paper)
26% identity, 74% coverage: 9:164/211 of query aligns to 688:884/929 of 6lodB

query
sites
6lodB

D

D

A

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N

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C

I
x
N

E
x
S

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C

N
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N

A
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A

C
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C

V

V

T

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A

A

C
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C

K

Q

N

S

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E

H
x
N

D

N

I

I

P

P

-

V

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G

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K

-

D

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E

-

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W

W

G

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N

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E

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x
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I
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I

T

R

L
x
I

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D

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Q

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Y

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G

-

D

D

E

G

H

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P

G

N

E

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M

A
x
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C
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C

M
x
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x
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C

N

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P

C
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C

A

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A

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C

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A

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x
A

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Y
x
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A

A

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G

G

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N

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x
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x
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x
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G

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Y

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C

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x
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F

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N

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Y

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Y

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M

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K

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x
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N

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E

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x
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D

D

binding fe3-s4 cluster: V758 (= V66), C759 (= C67), P760 (= P68), A763 (≠ C71), C779 (= C87), V780 (≠ I88), G781 (= G89), T782 (≠ C90), K783 (≠ G91), Y784 (= Y92), C785 (= C93), M838 (= M116)
binding heme c: V765 (≠ Y73), N777 (≠ D85), R778 (≠ L86), R852 (≠ E133), I853 (≠ E134), R856 (≠ K137)
binding iron/sulfur cluster: C692 (= C13), N693 (≠ I14), S694 (≠ E15), C695 (= C16), N696 (= N17), A697 (= A18), C698 (= C19), C702 (= C23), N706 (≠ H27), W724 (≠ V38), I725 (= I39), I727 (≠ L41), L746 (≠ A54), C747 (= C55), Q748 (≠ M56), Q749 (≠ H57), C750 (= C58), P754 (= P62), C755 (= C63), N772 (≠ V80), C789 (= C97), Y791 (≠ F99), V793 (≠ A101), R794 (≠ P102), K840 (= K118), C841 (= C119), T842 (= T120), F843 (= F121), C844 (= C122), T869 (≠ P149), A870 (≠ L150), C871 (= C151), C875 (= C155), T877 (= T157), I880 (≠ L160)

Sites not aligning to the query:

binding [(2S)-2-octadecanoyloxypropyl] octadecanoate: 1, 3

1kqfB Formate dehydrogenase n from e. Coli (see paper)
28% identity, 85% coverage: 2:181/211 of query aligns to 27:207/289 of 1kqfB

query
sites
1kqfB

A

A

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x
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x
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A

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C

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C

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x
N

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x
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A

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x
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binding protoporphyrin ix containing fe: Y137 (= Y92)
binding iron/sulfur cluster: K31 (≠ F6), C38 (= C13), I39 (= I14), G40 (≠ E15), C41 (= C16), K42 (≠ N17), A43 (= A18), C44 (= C19), C48 (= C23), N52 (≠ H27), T77 (≠ G32), M79 (≠ N34), K96 (≠ S52), C99 (= C55), M100 (= M56), H101 (= H57), C102 (= C58), P105 (= P61), G106 (≠ P62), C107 (= C63), C111 (= C67), P112 (= P68), A116 (≠ C71), I117 (≠ F72), V125 (= V80), C132 (= C87), I133 (= I88), G134 (= G89), C135 (= C90), G136 (= G91), Y137 (= Y92), C138 (= C93), C142 (= C97), F144 (= F99), I146 (≠ A101), P147 (= P102), V156 (≠ M116), K158 (= K118), C159 (= C119), T160 (= T120), L161 (≠ F121), C162 (= C122), P172 (= P149), A173 (≠ L150), C174 (= C151), C178 (= C155), P179 (≠ S156), I183 (≠ L160)

Sites not aligning to the query:

binding protoporphyrin ix containing fe: 252, 257

P0AAJ3 Formate dehydrogenase, nitrate-inducible, iron-sulfur subunit; Anaerobic formate dehydrogenase iron-sulfur subunit; Formate dehydrogenase-N subunit beta; FDH-N subunit beta from Escherichia coli (strain K12) (see paper)
28% identity, 85% coverage: 2:181/211 of query aligns to 28:208/294 of P0AAJ3

query
sites
P0AAJ3

A

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C

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P

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S

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A

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D

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Y

C39 (= C13) binding
C42 (= C16) binding
C45 (= C19) binding
C49 (= C23) binding
C100 (= C55) binding
C103 (= C58) binding
C108 (= C63) binding
C112 (= C67) binding
C133 (= C87) binding
C136 (= C90) binding
C139 (= C93) binding
C143 (= C97) binding
C160 (= C119) binding
C163 (= C122) binding
C175 (= C151) binding
C179 (= C155) binding

6f0kB Alternative complex iii (see paper)
27% identity, 82% coverage: 9:181/211 of query aligns to 729:933/961 of 6f0kB

query
sites
6f0kB

D

D

A

L

E

N

R

A

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C

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x
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x
G

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C

N
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N

A
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A

C
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C

V

I

T

V

A

A

C
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C

K

D

N

S

E

E

H

N

D

N

I

I

P

P

W

M

-

V

-

G

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K

-

N

-

E

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V

G

G

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N

G

R

R

R

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M

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x
W

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x
L

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I

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M

H
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H

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C

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N

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P

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C

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C

A

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D

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N

L

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G

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x
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Y

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C

F

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Y

N

A

N

C
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C

P

P

F

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K

A

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x
R

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R

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P

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D

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N

-

F

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G

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M

D

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K

K

C
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C

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Y

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C

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x
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N

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N

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x
A

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C

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C

S

P

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A

R

E

A

A

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A

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G

G

D

D

-

L

G

N

D

D

V

P

L

N

A

N

D

A

I

V

Y

V

K

K

E

Q

R

R

T

Q

V

N

R

A

R

R

G

R

Y

Y

binding fe3-s4 cluster: C803 (= C67), V805 (= V69), M818 (≠ H82), C823 (= C87), I824 (= I88), G825 (= G89), T826 (≠ C90), R827 (≠ G91), Y828 (= Y92), C829 (= C93), M869 (= M116)
binding heme c: A806 (≠ D70), N821 (≠ D85), R822 (≠ L86), R880 (≠ E133), Q883 (= Q136), R884 (≠ K137), N887 (≠ T140)
binding iron/sulfur cluster: C733 (= C13), T734 (≠ I14), G735 (≠ E15), C736 (= C16), N737 (= N17), A738 (= A18), C739 (= C19), C743 (= C23), W765 (vs. gap), L766 (vs. gap), I768 (vs. gap), C791 (= C55), M792 (= M56), H793 (= H57), C794 (= C58), P798 (= P62), C799 (= C63), N816 (≠ V80), C833 (= C97), R838 (vs. gap), C872 (= C119), Y874 (≠ F121), C875 (= C122), A901 (vs. gap), C902 (= C151), C906 (= C155)

Sites not aligning to the query:

binding heme c: 719

7qv7A Cryo-em structure of hydrogen-dependent co2 reductase. (see paper)
29% identity, 86% coverage: 7:187/211 of query aligns to 6:174/174 of 7qv7A

query
sites
7qv7A

L

I

C

A

D

D

A

P

E

K

R

R

C
|
C

I
x
L

E
x
G

C
|
C

N
x
Y

A

T

C
|
C

V

I

T

A

A

A

C
|
C

K

A

N

F

E

V

H
|
H

D

E

I

-

P

E

W

Q

G

G

I

L

N

Q

-

P

-

F

-

P

R

R

R
x
L

R

Y

V

L

I

T

T

Y

L

T

K

S

D

E

G

G

V

I

P

-

G

-

E

-

R

-

S

-

I

M

S

P

M

I

A

Q

C
|
C

M
x
R

H

H

C
|
C

N

E

D

D

P

A

P
|
P

C
|
C

A

A

A

E

V

V

C
|
C

P

P

V

V

D

E

C

A

F
x
I

Y

K

Q

K

T

E

A

G

D

N

G

A

V

I

L

I

H

D

S

E

K

K

D

A

L

-

C
|
C

I
|
I

G
|
G

C
|
C

G

K

Y

T

C
|
C

F

L

Y

L

A

A

C
|
C

P

S

F

F

G

G

A

-

P

-

Q

-

Y

-

P

-

Q

-

A

A

T
x
I

N

D

F
|
F

G

S

G

V

R

Q

G

D

K

S

M

L

D

E

K

Q

C

S

T

I

F

F

C

-

T

K

G

D

G

I

P

K

E

E

A

N

D

L

N

M

T

R

M

I

E

V

E
x
A

Y

V

Q

K

K
x
C

Y
x
D

G
x
L

T
x
C

N

N

R

F

L

R

A

E

E

E

G

G

K

-

L

-

P
|
P

L
x
A

C
|
C

A

V

E

Q

M

F

C
|
C

S
x
P

T
|
T

R

K

A

A

L

L

M

K

A

L

G

V

D

D

G

G

D

D

V

E

L

I

A

N

D

K

I

M

Y

V

K

K

-

N

E

K

R

R

T

T

V

V

R

N

R

V

G

E

Y

S

G

L

S

L

G

S

A

V

W

Y

G

G

binding iron/sulfur cluster: C12 (= C13), L13 (≠ I14), G14 (≠ E15), C15 (= C16), Y16 (≠ N17), C18 (= C19), C22 (= C23), H26 (= H27), L37 (≠ R36), C51 (= C55), R52 (≠ M56), C54 (= C58), P58 (= P62), C59 (= C63), C63 (= C67), I68 (≠ F72), C82 (= C87), I83 (= I88), G84 (= G89), C85 (= C90), C88 (= C93), C92 (= C97), I97 (≠ T108), F99 (= F110), A122 (≠ E134), C125 (≠ K137), D126 (≠ Y138), L127 (≠ G139), C128 (≠ T140), P135 (= P149), A136 (≠ L150), C137 (= C151), C141 (= C155), P142 (≠ S156), T143 (= T157)

7z0sB Structure of the escherichia coli formate hydrogenlyase complex (anaerobic preparation, without formate dehydrogenase h) (see paper)
34% identity, 47% coverage: 6:104/211 of query aligns to 5:99/170 of 7z0sB

query
sites
7z0sB

F

V

L

I

C

A

D

D

A

S

E

T

R

L

C
|
C

I
|
I

E
x
G

C
|
C

N
x
H

A
x
T

C
|
C

V

E

T

A

A

A

C
|
C

K

S

N

E

-

T

-
x
H

-

R

E

Q

H

H

D

G

I

L

P

Q

W

S

G

M

I

P

N
x
R

R
x
L

R

R

R

V

V

M

I

L

T

N

L

E

K

K

D

E

G

S

V

A

P
|
P

G

-

E

-

R

-

S

-

I

-

S

-

M

Q

A
x
L

C
|
C

M
x
H

H
|
H

C
|
C

N

E

D

D

P

A

P

P

C
|
C

A

A

A

V

V

V

C
|
C

P
|
P

V

V

D

N

C

A

F
x
I

Y

T

Q

R

T

V

A

-

D

D

G

G

V

A

V
|
V

L

Q

H
x
L

S

N

K

E

D

S

L

L

C
|
C

I
x
V

G
x
S

C
|
C

G
x
K

Y
x
L

C
|
C

F

G

Y

I

A

A

C
|
C

P

P

F

F

G

G

A
|
A

P
x
I

Q

E

Y

F

binding iron/sulfur cluster: C12 (= C13), I13 (= I14), G14 (≠ E15), C15 (= C16), H16 (≠ N17), T17 (≠ A18), C18 (= C19), C22 (= C23), H26 (vs. gap), R36 (≠ N34), L37 (≠ R35), P48 (= P46), L50 (≠ A54), C51 (= C55), H52 (≠ M56), H53 (= H57), C54 (= C58), C59 (= C63), C63 (= C67), P64 (= P68), I68 (≠ F72), V75 (= V80), L77 (≠ H82), C82 (= C87), V83 (≠ I88), S84 (≠ G89), C85 (= C90), K86 (≠ G91), L87 (≠ Y92), C88 (= C93), C92 (= C97), A96 (= A101), I97 (≠ P102)

Sites not aligning to the query:

binding iron/sulfur cluster: 140, 142, 143, 144, 145, 146, 153, 154, 155, 159, 160, 161, 163, 164

6x6uB Wor5 from pyrococcus furiosus, taurine-bound (see paper)
30% identity, 63% coverage: 3:134/211 of query aligns to 2:127/167 of 6x6uB

query
sites
6x6uB

R

R

M

I

K

W

F

I

L

L

C

I

D

T

A

P

E
x
D

R

K

C
|
C

I
x
S

E
x
G

C
|
C

N
x
R

A

L

C
|
C

V

E

T

V

A

T

C
|
C

K

S

N

L

E

E

H
|
H

D

E

-

G

I

I

P

I

W

W

G

P

-

E

I

A

N

S

R
|
R

R
x
I

R

R

V
|
V

I

F

T

E

L

L

K

F

D

P

G

G

V

I

P

-

G

-

E

-

R

-

S

N

I

V

S
x
P

M

H

A

T

C
|
C

M
x
V

H
x
Q

C
|
C

N

P

D

D

P

Y

P
|
P

C
|
C

A

V

A

N

V

A

C
|
C

P
|
P

V

T

D

N

C

A

F
x
L

-

S

Y

V

Q

D

T

E

A

K

D

T

G

G

V

A

V

V

L

V

H

V

S

N

K

E

D

E

L

K

C
|
C

I
|
I

G
x
T

C
|
C

G
|
G

Y
x
A

C
|
C

F

V

Y

L

A

A

C
|
C

P

P

F

G

G

K

A
x
V

P
|
P

Q

R

Y

I

P

P

Q

-

A

-

T

-

N

-

F

-

G

A

G

G

R

K

G

G

K

S

M

V

D

V

K

I

C
|
C

T
x
D

F
x
L

C
|
C

T

G

G

G

G

N

P
|
P

E
x
K

A
x
C

D

V

N

E

T

I

M
x
C

E

H

E

E

binding phosphate ion: D10 (≠ E11)
binding iron/sulfur cluster: C12 (= C13), S13 (≠ I14), G14 (≠ E15), C15 (= C16), R16 (≠ N17), C18 (= C19), C22 (= C23), H26 (= H27), R36 (= R35), I37 (≠ R36), V39 (= V38), P49 (≠ S52), C52 (= C55), V53 (≠ M56), Q54 (≠ H57), C55 (= C58), P59 (= P62), C60 (= C63), C64 (= C67), P65 (= P68), L69 (≠ F72), C85 (= C87), I86 (= I88), T87 (≠ G89), C88 (= C90), G89 (= G91), A90 (≠ Y92), C91 (= C93), C95 (= C97), V99 (≠ A101), P100 (= P102), C112 (= C119), D113 (≠ T120), L114 (≠ F121), C115 (= C122), P119 (= P126), K120 (≠ E127), C121 (≠ A128), C125 (≠ M132)

Sites not aligning to the query:

7qv7B Cryo-em structure of hydrogen-dependent co2 reductase. (see paper)
38% identity, 44% coverage: 12:104/211 of query aligns to 13:115/183 of 7qv7B

query
sites
7qv7B

R

K

C
|
C

I
|
I

E
x
G

C
|
C

N
x
K

A
|
A

C
|
C

V

E

T

V

A

A

C
|
C

-

F

-

A

-

V

-
x
H

-

N

K

R

N

N

E

N

H

H

-

V

-

G

-

A

-

T

-

V

-

G

-

T

-

V

D

S

I

I

P

P

W

V

G

-

I

I

N

P

R
|
R

R

L

R

H

V

L

I

I

T

K

L

T

K

E

D

H

G

G

V

-

P

-

G

-

E

-

R

-

S

T

I

M

S

P

M

I

A

Q

C
|
C

M
x
R

H
|
H

C
|
C

N

E

D

D

P
x
A

P

P

C
|
C

A

A

A

N

V

V

C
|
C

P

T

V

V

D

G

C
x
A

F
x
I

Y

K

Q

R

T

E

A

G

D

N

G

A

V

I

V

V

L

V

H

D

S

E

K

K

D

-

L

L

C
|
C

I
|
I

G

G

C
|
C

G

K

Y

S

C
|
C

F

L

Y

L

A

A

C
|
C

P

P

F

F

G

G

A

A

-
x
I

-

E

-

L

P

P

Q

Q

Y

Y

binding iron/sulfur cluster: C14 (= C13), I15 (= I14), G16 (≠ E15), C17 (= C16), K18 (≠ N17), A19 (= A18), C20 (= C19), C24 (= C23), H28 (vs. gap), R48 (= R35), C63 (= C55), R64 (≠ M56), H65 (= H57), C66 (= C58), A69 (≠ P61), C71 (= C63), C75 (= C67), A79 (≠ C71), I80 (≠ F72), C94 (= C87), I95 (= I88), C97 (= C90), C100 (= C93), C104 (= C97), I109 (vs. gap)

Sites not aligning to the query:

binding iron/sulfur cluster: 139, 140, 141, 142, 148, 149, 150, 154, 155, 158, 159

6btmB Structure of alternative complex iii from flavobacterium johnsoniae (wild type) (see paper)
24% identity, 57% coverage: 9:128/211 of query aligns to 689:874/948 of 6btmB

query
sites
6btmB

D

D

A

L

E

N

R

A

C

C

I

T

E

G

C

C

N

G

A

A

C

C

V

V

T

I

A

A

C

C

K

H

N

A

E

E

H

N

D

N

I

V

P

P

-

V

-

G

-

K

-

A

-

E

-

V

-

R

-

S

-

R

-

D

-

M

-

H

W

W

-

L

-

R

-

I

-

D

-

R

-

Y

-

S

-

E

-

S

-

T

-

F

-

E

G

G

I

D

N

N

R

E

R

R

R

-

V

-

I

-

T

-

L

-

K

K

D

E

G

G

V

I

P

A

G

G

-

L

E

S

R

S

S

S

I

L

S

S

-

T

-

F

-

N

-

E

-

M

-

E

-

K

-

P

-

G

-

D

-

N

-

P

-

Q

-

V

-

A

-

F

-

Q

-

P

M

V

A

M

C
|
C

M
x
Q

H

H

C
|
C

N

N

D

H

P

A

P

P

C
|
C

A

E

A

T

V

V

C
|
C

P

P

V

V

D

A

C

A

F

T

Y

S

Q

H

T

G

A

R

D

Q

G

G

V

Q

V
x
N

L

H

H

M

S

A

K

Y

D
x
N

L
x
R

C
|
C

I
x
V

G

G

C
x
T

G

R

Y

Y

C
|
C

F

A

Y

N

A

N

C
|
C

P

P

F

Y

G

K

A

V

P
x
R

Q

R

Y

F

-

N

-

W

-

F

-

L

-

Y

-

N

-

K

-

N

-

S

-

E

-

F

-

D

-

Y

-

H

-

M

-

N

-

D

-

L

-

G

-

R

-

M

-

V

-

L

-

N

P

P

Q

D

A

-

T

V

N

N

F

V

G

R

G

S

R

R

G

G

K

V

M
|
M

D

E

K

K

C

C

T

S

F

F

C

C

T

I

G

Q

G

S

P

T

E

Q

A

A

binding fe3-s4 cluster: C789 (= C67), C809 (= C87), V810 (≠ I88), T812 (≠ C90), C815 (= C93), M862 (= M116)
binding heme c: N807 (≠ D85), R808 (≠ L86)
binding iron/sulfur cluster: C777 (= C55), Q778 (≠ M56), C780 (= C58), C785 (= C63), N802 (≠ V80), C819 (= C97), R824 (≠ P102)

Sites not aligning to the query:

binding (2R)-3-{[(2R)-2-(decanoylamino)-3-hydroxypropyl]sulfanyl}propane-1,2-diyl ditetradecanoate: 1, 2

5ch7B Crystal structure of the perchlorate reductase pcrab - phe164 gate switch intermediate - from azospira suillum ps (see paper)
29% identity, 58% coverage: 51:173/211 of query aligns to 129:231/329 of 5ch7B

query
sites
5ch7B

I

L

S
x
P

M

R

A
x
M

C
|
C

M
x
N

H
|
H

C
|
C

N

T

D

K

P
|
P

P

A

C
|
C

A

L

A

E

V

A

C
|
C

P

P

V

N

D

E

C

A

F
x
I

Y

Y

Q

K

-

R

T

E

A

Q

D

D

G

G

V

I

V

V

L

V

H

I

S

H

K

Q

D

D

L

K

C
|
C

I
x
K

G
|
G

C
x
A

G
x
Q

Y
x
A

C
|
C

F

V

Y

Q

A

S

C
|
C

P

P

F

Y

G

A

A

K

P
|
P

Q

Y

Y

F

P

N

Q

P

A

L

T

T

N

N

F

-

G

-

R

-

G

-

K

K

M
x
A

D

N

K
|
K

C
|
C

T
x
I

F
x
G

C
|
C

T

F

G

P

G

-

P

-

E

-

A

-

D

-

N

-

T

-

M

-

E

-

Y

-

Q

-

K

-

Y

-

G

-

T

-

N

-

R

R

L

I

A

E

E

Q

G

G

K

V

L

A

P
|
P

L
x
A

C
|
C

A

V

E

A

M

Q

C
|
C

S
x
V

T
x
G

R

R

A

A

L

M

M

H

A

V

G

G

-

F

D

V

G

D

D

D

V

V

L

N

A

S

D

S

I

V

Y

Y

K

K

binding fe3-s4 cluster: C145 (= C67), I150 (≠ F72), C166 (= C87), K167 (≠ I88), G168 (= G89), A169 (≠ C90), Q170 (≠ G91), A171 (≠ Y92), C172 (= C93), A190 (≠ M116)
binding iron/sulfur cluster: P130 (≠ S52), M132 (≠ A54), C133 (= C55), N134 (≠ M56), H135 (= H57), C136 (= C58), P139 (= P61), C141 (= C63), C176 (= C97), P181 (= P102), K192 (= K118), C193 (= C119), I194 (≠ T120), G195 (≠ F121), C196 (= C122), P206 (= P149), A207 (≠ L150), C208 (= C151), C212 (= C155), V213 (≠ S156), G214 (≠ T157)

Sites not aligning to the query:

binding iron/sulfur cluster: 17, 18, 19, 20, 21, 22, 23, 27, 31, 43, 43, 45
binding sulfite ion: 29, 33, 106, 107, 112

3egwB The crystal structure of the narghi mutant narh - c16a
36% identity, 35% coverage: 55:128/211 of query aligns to 184:253/509 of 3egwB

query
sites
3egwB

C
|
C

M
x
E

H
|
H

C
|
C

N

L

D

N

P
|
P

P

A

C
|
C

A

V

A

A

V

T

C
|
C

P

P

V
x
S

D

G

C

A

F
x
I

Y

Y

Q

K

-

R

T

E

A

E

D

D

G

G

V

I

V
|
V

L

L

H

I

S

D

K

Q

D

D

L

K

C
|
C

I
x
R

G
|
G

C
x
W

G
x
R

Y
x
M

C
|
C

F

I

Y

T

A

G

C
|
C

P

P

F
x
Y

G

K

A

K

P
x
I

Q

Y

Y

F

P

N

Q

W

A

K

T

S

N

-

F

-

G

-

R

-

G

G

K

K

M
x
S

D

E

K
|
K

C
|
C

T
x
I

F
|
F

C
|
C

T

Y

G

P

G

R

P

I

E

E

A

A

binding fe3-s4 cluster: C196 (= C67), S198 (≠ V69), I201 (≠ F72), C217 (= C87), R218 (≠ I88), G219 (= G89), W220 (≠ C90), R221 (≠ G91), M222 (≠ Y92), C223 (= C93), S241 (≠ M116)
binding protoporphyrin ix containing fe: W220 (≠ C90), R221 (≠ G91)
binding iron/sulfur cluster: C184 (= C55), E185 (≠ M56), H186 (= H57), C187 (= C58), P190 (= P61), C192 (= C63), V210 (= V80), C227 (= C97), Y229 (≠ F99), I232 (≠ P102), K243 (= K118), C244 (= C119), I245 (≠ T120), F246 (= F121), C247 (= C122)

Sites not aligning to the query:

binding fe3-s4 cluster: 17, 18, 19, 20, 21, 22, 181, 263, 264, 265, 267, 268
binding protoporphyrin ix containing fe: 88, 89
binding iron/sulfur cluster: 26, 30, 41, 42, 183, 257, 258, 259

P11349 Respiratory nitrate reductase 1 beta chain; Nitrate reductase A subunit beta; Quinol-nitrate oxidoreductase subunit beta; EC 1.7.5.1 from Escherichia coli (strain K12) (see 2 papers)
36% identity, 35% coverage: 55:128/211 of query aligns to 184:253/512 of P11349

query
sites
P11349

C
|
C

M

E

H

H

C
|
C

N

L

D

N

P

P

P

A

C
|
C

A

V

A

A

V

T

C
|
C

P

P

V

S

D

G

C

A

F

I

Y

Y

Q

K

-

R

T

E

A

E

D

D

G

G

V

I

V

V

L

L

H

I

S

D

K

Q

D

D

L

K

C
|
C

I

R

G

G

C

W

G

R

Y

M

C
|
C

F

I

Y

T

A

G

C
|
C

P

P

F

Y

G

K

A

K

P

I

Q

Y

Y

F

P

N

Q

W

A

K

T

S

N

-

F

-

G

-

R

-

G

G

K

K

M

S

D

E

K

K

C
|
C

T

I

F

F

C
|
C

T

Y

G

P

G

R

P

I

E

E

A

A

C184 (= C55) binding
C187 (= C58) binding
C192 (= C63) binding
C196 (= C67) binding
C217 (= C87) binding
C223 (= C93) binding
C227 (= C97) binding
C244 (= C119) binding
C247 (= C122) binding

Sites not aligning to the query:

16 binding
19 binding
22 binding
26 binding
259 binding
263 binding

4v4cB Pyrogallol hydroxytransferase small subunit (see paper)
27% identity, 58% coverage: 1:122/211 of query aligns to 1:129/274 of 4v4cB

query
sites
4v4cB

M

M

A

E

R

Q

M

Y

K

Y

F

M

L

V

C

I

D

D

A

V

E

A

R

K

C
|
C

I
x
Q

E
x
D

C
|
C

N
|
N

A
x
N

C
|
C

V

F

T

M

A

G

C
|
C

K

M

N

D

E

E

H
|
H

D

E

I

L

-

N

P

E

W

W

-

P

-

G

-

Y

-

T

-

A

-

S

-

M

-

Q

-

R

-

G

-

H

-

R

-

W

-

M

G

N

I

I

N

E

R

R

R

E

V

R

I

G

T

T

L

Y

K

P

D

R

G

N

V

D

P
x
I

G
x
N

E

Y

R

R

S

P

I

T

S

P

M

-

A

-

C
|
C

M
|
M

H
|
H

C
|
C

N

E

D

N

P
x
A

P

P

C
|
C

A

V

A

A

V

K

C

G

P

N

V

-

D

G

C

A

F

V

Y

Y

Q

Q

T

R

A

E

D

D

G

G

V

I

V
|
V

L

L

H

I

S

D

K

P

D

E

L

K

C

A

I

K

G

G

C

K

G

K

Y

E

C

L

F

L

Y

D

A

T

C
|
C

P

P

F

Y

G

G

A
x
V

P

M

Q

Y

Y

W

P

N

Q

E

A

E

T

E

N

N

F

V

G

A

G

-

R

-

G

-

K

-

M

-

D

Q

K

K

C
|
C

T
|
T

F
x
M

C
|
C

binding calcium ion: I61 (≠ P46), N62 (≠ G47)
binding iron/sulfur cluster: C13 (= C13), Q14 (≠ I14), D15 (≠ E15), C16 (= C16), N17 (= N17), N18 (≠ A18), C19 (= C19), C23 (= C23), H27 (= H27), C68 (= C55), M69 (= M56), H70 (= H57), C71 (= C58), A74 (≠ P61), C76 (= C63), V92 (= V80), C109 (= C97), V113 (≠ A101), C126 (= C119), T127 (= T120), M128 (≠ F121), C129 (= C122)

Sites not aligning to the query:

binding iron/sulfur cluster: 143, 144, 145, 149, 151, 153, 154

2ivfB Ethylbenzene dehydrogenase from aromatoleum aromaticum (see paper)
32% identity, 34% coverage: 51:122/211 of query aligns to 132:199/337 of 2ivfB

query
sites
2ivfB

I

L

S

A

M

R

A
x
M

C
|
C

M
x
N

H
|
H

C
|
C

N

T

D

N

P
|
P

P

A

C
|
C

A

L

A

A

V

A

C
|
C

P

P

V
x
T

D

G

C

A

F
x
I

Y

Y

Q

K

T

R

A

E

D

D

-

N

G

G

V

I

V
|
V

L

L

H

V

S

D

K

Q

D

E

L

R

C
|
C

I
x
K

G
|
G

C
x
H

G
x
R

Y
x
H

C
|
C

F

V

Y

E

A

A

C
|
C

P

P

F
x
Y

G

K

A
|
A

P
x
I

Q

Y

Y

F

P

N

Q

P

A

V

T

S

N

Q

F

-

G

-

R

-

G

-

K

T

M
x
S

D

E

K
|
K

C
|
C

T
x
I

F
x
L

C
|
C

binding fe3-s4 cluster: C148 (= C67), T150 (≠ V69), I153 (≠ F72), C169 (= C87), K170 (≠ I88), G171 (= G89), H172 (≠ C90), R173 (≠ G91), H174 (≠ Y92), C175 (= C93), S193 (≠ M116)
binding protoporphyrin ix containing fe: T150 (≠ V69), K170 (≠ I88), H172 (≠ C90)
binding iron/sulfur cluster: M135 (≠ A54), C136 (= C55), N137 (≠ M56), H138 (= H57), C139 (= C58), P142 (= P61), C144 (= C63), V162 (= V80), C179 (= C97), Y181 (≠ F99), A183 (= A101), I184 (≠ P102), K195 (= K118), C196 (= C119), I197 (≠ T120), L198 (≠ F121), C199 (= C122)

Sites not aligning to the query:

binding iron/sulfur cluster: 13, 14, 15, 16, 17, 18, 19, 23, 27, 38, 39, 41, 209, 210, 211, 215, 217, 219, 220

Query Sequence

>AZOBR_RS18730 AZOBR_RS18730 formate dehydrogenase
MARMKFLCDAERCIECNACVTACKNEHDIPWGINRRRVITLKDGVPGERSISMACMHCND
PPCAAVCPVDCFYQTADGVVLHSKDLCIGCGYCFYACPFGAPQYPQATNFGGRGKMDKCT
FCTGGPEADNTMEEYQKYGTNRLAEGKLPLCAEMCSTRALMAGDGDVLADIYKERTVRRG
YGSGAWGWSTAYGQNDRGDAFSPGREGTGGS

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory