Comparing AZOBR_RS22710 FitnessBrowser__azobra:AZOBR_RS22710 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 18 hits to proteins with known functional sites (download)
3g4hA Crystal structure of human senescence marker protein-30 (zinc bound) (see paper)
30% identity, 95% coverage: 1:280/296 of query aligns to 4:280/297 of 3g4hA
4gncA Human smp30/gnl-1,5-ag complex (see paper)
30% identity, 95% coverage: 1:280/296 of query aligns to 5:281/298 of 4gncA
Sites not aligning to the query:
Q15493 Regucalcin; RC; Gluconolactonase; GNL; Senescence marker protein 30; SMP-30; EC 3.1.1.17 from Homo sapiens (Human) (see 2 papers)
30% identity, 95% coverage: 1:280/296 of query aligns to 6:282/299 of Q15493
4gnaA Mouse smp30/gnl-xylitol complex (see paper)
29% identity, 95% coverage: 1:280/296 of query aligns to 4:280/297 of 4gnaA
4gn9A Mouse smp30/gnl-glucose complex (see paper)
29% identity, 95% coverage: 1:280/296 of query aligns to 4:280/297 of 4gn9A
4gn8A Mouse smp30/gnl-1,5-ag complex (see paper)
29% identity, 95% coverage: 1:280/296 of query aligns to 4:280/297 of 4gn8A
Sites not aligning to the query:
4gn7A Mouse smp30/gnl (see paper)
29% identity, 95% coverage: 1:280/296 of query aligns to 4:280/297 of 4gn7A
Q9A9Z1 D-xylonolactone lactonase; Xylono-1,5-lactonase; EC 3.1.1.110 from Caulobacter vibrioides (strain ATCC 19089 / CIP 103742 / CB 15) (Caulobacter crescentus) (see paper)
30% identity, 96% coverage: 8:291/296 of query aligns to 10:283/289 of Q9A9Z1
7pldB Caulobacter crescentus xylonolactonase with (r)-4-hydroxy-2- pyrrolidone (see paper)
30% identity, 96% coverage: 8:291/296 of query aligns to 10:283/289 of 7pldB
7plbB Caulobacter crescentus xylonolactonase with d-xylose (see paper)
30% identity, 96% coverage: 8:291/296 of query aligns to 10:283/289 of 7plbB
5gx1A Luciferin-regenerating enzyme collected with serial synchrotron rotational crystallography with accumulated dose of 1.1 mgy (1st measurement) (see paper)
27% identity, 84% coverage: 13:262/296 of query aligns to 15:270/307 of 5gx1A
5d9bA Luciferin-regenerating enzyme solved by siras using xfel (refined against native data) (see paper)
27% identity, 84% coverage: 13:262/296 of query aligns to 15:270/307 of 5d9bA
7rizA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound 2-hydroxyquinoline (see paper)
28% identity, 55% coverage: 104:266/296 of query aligns to 120:287/306 of 7rizA
Sites not aligning to the query:
8dk0A Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound (s)gamma- valerolactone (see paper)
27% identity, 55% coverage: 104:266/296 of query aligns to 115:274/293 of 8dk0A
Sites not aligning to the query:
8djzA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound product (see paper)
27% identity, 55% coverage: 104:266/296 of query aligns to 115:274/293 of 8djzA
Sites not aligning to the query:
8djfA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound tetrahedral intermediate (see paper)
27% identity, 55% coverage: 104:266/296 of query aligns to 115:274/293 of 8djfA
Sites not aligning to the query:
7risA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound phosphate (see paper)
24% identity, 82% coverage: 24:266/296 of query aligns to 20:274/293 of 7risA
Sites not aligning to the query:
3e5zA X-ray structure of the putative gluconolactonase in protein family pf08450. Northeast structural genomics consortium target drr130.
27% identity, 51% coverage: 112:261/296 of query aligns to 125:273/290 of 3e5zA
Sites not aligning to the query:
>AZOBR_RS22710 FitnessBrowser__azobra:AZOBR_RS22710
LEAVFDPDLRNGTGENPVWDAERGSWTWIDIPARTIHRLDPSSGAHRRWTLPEMIGSLVL
RPDGGVVCACETGVFDVDLPGEGGEAVVTALATHRFPKEGMRFNDGRCDRQGRFWLSSMV
MDISKGDSSGLWHRFTRADGLTETGTGGYIIPNGSAFSPDGRTLYASDSHRDVRMVWAWD
YDTDTGTADNRRPFVDMRAMVGRPDGAAVDIDGCYWICCLDEGCIKRFTPNGDLDRRIEV
PMRKPTMCAFGGPDLRTMLVTSLSRGPADLAEDPHGGRVLMFDPGAQGLPEPRLAD
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory