SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing AZOBR_RS27130 AZOBR_RS27130 polyamine ABC transporter substrate-binding protein to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 20 (the maximum) hits to proteins with known functional sites (download)

5otcA Structure of the periplasmic binding protein (pbp) noct from agrobacterium tumefaciens c58 in complex with noroctopinic acid. (see paper)
37% identity, 89% coverage: 30:259/259 of query aligns to 4:254/256 of 5otcA

query
sites
5otcA

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P

binding (2~{S})-5-azanyl-2-(2-hydroxy-2-oxoethylamino)pentanoic acid: E9 (= E35), Y12 (= Y38), W50 (= W76), A68 (≠ T94), G70 (≠ N96), R75 (= R101), Q138 (= Q141), T141 (= T144), S142 (≠ T145), H143 (= H146), S180 (≠ T184)

5ovzA High resolution structure of the pbp noct in complex with nopaline (see paper)
37% identity, 90% coverage: 26:259/259 of query aligns to 1:255/259 of 5ovzA

query
sites
5ovzA

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binding N-[(1S)-4-carbamimidamido-1-carboxybutyl]-D-glutamic acid: E10 (= E35), Y13 (= Y38), W51 (= W76), A68 (= A93), A69 (≠ T94), G71 (≠ N96), R76 (= R101), M91 (≠ A116), Q139 (= Q141), T142 (= T144), S143 (≠ T145), H144 (= H146), S181 (≠ T184), V213 (= V217)

5otaA Structure of the periplasmic binding protein (pbp) noct from agrobacterium tumefaciens c58 in complex with octopinic acid (see paper)
37% identity, 89% coverage: 30:259/259 of query aligns to 4:254/254 of 5otaA

query
sites
5otaA

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binding (2~{S})-5-azanyl-2-[[(2~{R})-1-oxidanyl-1-oxidanylidene-propan-2-yl]amino]pentanoic acid: E9 (= E35), Y12 (= Y38), W50 (= W76), A68 (≠ T94), G70 (≠ N96), R75 (= R101), M90 (≠ A116), Q138 (= Q141), T141 (= T144), S142 (≠ T145), H143 (= H146), S180 (≠ T184)

5ot9A Structure of the periplasmic binding protein (pbp) noct from a.Tumefaciens c58 in complex with histopine. (see paper)
37% identity, 89% coverage: 30:259/259 of query aligns to 4:254/254 of 5ot9A

query
sites
5ot9A

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binding Histopine: E9 (= E35), Y12 (= Y38), W50 (= W76), A67 (= A93), A68 (≠ T94), R75 (= R101), M90 (≠ A116), Q138 (= Q141), T141 (= T144), S142 (≠ T145), H143 (= H146), S180 (≠ T184)

4powA Structure of the pbp noct in complex with pyronopaline (see paper)
37% identity, 89% coverage: 30:259/259 of query aligns to 4:254/254 of 4powA

query
sites
4powA

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K

D

P

W

L

V

T

K

D

A

K

D

P

A

D

S

N

K

K

S

D

L

L

Q

K

L

M

V

F

G

G

K

-

P

P

L

R

V

M

D

T

A

G

E

G

V

L

F

F

G

G

P

K

G

G

V

V

G

G

V

V

G

G

L

I

R

R

K

K

E

E

D

D

A

A

D

D

L

L

K

K

A

A

A

L

F

F

D

D

A

K

A

A

I

I

A

D

S

A

V

A

V

I

Q

A

D

D

G

G

T

T

L

V

A

Q

R

K

I

L

A

S

A

Q

K

Q

Y

W

V

F

D

G

F

Y

T

D

V

A

T

S

P

P

binding 1-[(1S)-4-carbamimidamido-1-carboxybutyl]-5-oxo-D-proline: E9 (= E35), Y12 (= Y38), W50 (= W76), A67 (= A93), A68 (≠ T94), G70 (≠ N96), R75 (= R101), M90 (≠ A116), Q138 (= Q141), T141 (= T144), S142 (≠ T145), H143 (= H146), S180 (≠ T184)

5itoA Structure of the periplasmic binding protein m117n-noct from a. Tumefaciens in complex with octopine (see paper)
37% identity, 90% coverage: 26:259/259 of query aligns to 1:255/255 of 5itoA

query
sites
5itoA

D

D

G

Y

P

K

P

S

L

I

R

T

I

I

A

A

T

T

E
|
E

G

G

A

S

Y
|
Y

P

A

P

P

F

Y

N

N

M

F

T

K

S

D

P

A

D

G

G

G

T

K

L

L

G

I

G

G

L

F

E

D

V

I

E

D

L

L

A

G

N

N

A

D

L

L

C

C

E

K

R

R

I

M

K

N

R

I

R

E

C

C

T

K

L

F

V

V

A

E

Q

Q

D

A

W
|
W

D

D

G

G

I

I

P

P

G

S

L

L

L

T

S

A

R

G

R

R

Y

Y

D

D

A

A

I

I

M

M

A
|
A

T
x
A

M

M

N
x
G

I

I

T

Q

P

P

E

A

R
|
R

A

E

K

K

A

V

I

I

A

A

F

F

S

S

A

R

P

P

Y

Y

M

L

V

L

V

T

P

P

A

N

Y

T

F

F

V

L

A

T

-

A

-

D

-

S

-

P

-

L

-

K

-

T

-

Q

-

V

-

A

-

I

-

E

-

N

-

L

-

P

-

L

-

D

-

N

-

I

-

T

-

P

-

E

T

Q

G

K

G

A

G

E

I

L

D

D

G

K

T

F

E

T

A

K

T

I

L

F

A

E

G

G

K

V

S

K

V

F

G

G

A

V

Q
|
Q

T

A

S

G

T
|
T

T
x
S

H
|
H

Y

E

R

A

Y

F

V

M

E

-

K

K

H

Q

F

M

G

M

K

P

T

S

V

V

S

Q

L

I

K

S

N

T

Y

Y

D

D

T

T

A

I

S

D

N

N

L

V

A

M

D

D

L

L

K

K

S

A

G

G

R

R

I

I

D

D

A

A

A

S

I

L

T

A

T
x
S

G

V

A

S

T

F

A

L

S

K

D

P

W

L

V

T

K

D

A

K

D

P

A

D

S

N

K

K

S

D

L

L

Q

K

L

M

V

F

G

G

K

-

P

P

L

R

V

M

D

T

A

G

E

G

V

L

F

F

G

G

P

K

G

G

V

V

G

G

V

V

G

G

L

I

R

R

K

K

E

E

D

D

A

A

D

D

L

L

K

K

A

A

A

L

F

F

D

D

A

K

A

A

I

I

A

D

S

A

V

A

V

I

Q

A

D

D

G

G

T

T

L

V

A

Q

R

K

I

L

A

S

A

Q

K

Q

Y

W

V

F

D

G

F

Y

T

D

V

A

T

S

P

P

binding octopine: E10 (= E35), Y13 (= Y38), W51 (= W76), A68 (= A93), A69 (≠ T94), G71 (≠ N96), R76 (= R101), Q139 (= Q141), T142 (= T144), S143 (≠ T145), H144 (= H146), S181 (≠ T184)

5orgA Structure of the periplasmic binding protein (pbp) occj from a. Tumefaciens b6 in complex with octopine. (see paper)
40% identity, 89% coverage: 30:259/259 of query aligns to 6:256/257 of 5orgA

query
sites
5orgA

L

I

R

T

I

I

A

A

T

T

E
|
E

G

G

A

G

Y
|
Y

P

A

P

P

F

W

N

N

M

F

T

S

S

G

P

P

D

G

G

G

T

K

L

L

G

D

G

G

L

F

E

E

V

I

E

D

L

L

A

A

N

N

A

A

L

L

C

C

E

E

R

K

I

M

K

K

R

A

R

K

C

C

T

Q

L

I

V

V

A

A

Q

Q

D

N

W
|
W

D

D

G

G

I

I

I

M

P

P

G

S

L

L

L

T

S

G

R

K

Y

Y

D

D

A

A

I

I

M

M

A
|
A

T
x
A

M
|
M

N
x
S

I

V

T

T

P

P

E

K

R
|
R

A

Q

K

E

A

V

I

I

A

G

F

F

S

S

A

I

P

P

Y

Y

M

A

V

A

V

G

P

I

A
x
N

Y

G

F

F

V

A

A

V

-

M

-

G

-

D

-

S

-

K

-

L

A

A

T

E

G

M

G

P

G

G

I

L

D

G

G

E

T

T

-

Y

-

S

-

L

-

D

-

S

-

Q

-

A

-

D

-

A

-

K

-

A

-

I

-

A

-

D

-

I

E

S

A

S

T

F

L

L

A

N

G

G

K

T

S

T

V

V

G

G

A

V

Q
|
Q

T

G

S

S

T
|
T

H

A

Y

S

R

T

Y

F

V

L

E

D

K

K

H

Y

F

F

G

K

K

G

T

S

V

V

S

D

L

I

K

K

N

E

Y

Y

D

K

T

S

A

V

S

E

N

E

L

H

L

N

A

L

D

D

L

L

K

T

S

S

G

G

R

R

I

L

D

D

A

A

A

V

I

L

T

A

T
x
N

G

A

A

T

T

V

A

L

S

A

D

A

W

A

V

I

K

E

A

K

D

P

A

E

S

M

K

K

S

G

L

A

Q

K

L

L

V

V

G

G

K

-

P

P

L

L

V

F

D

S

A

G

E

G

V

E

F

F

G

G

P

V

G

-

V

V

G

A

V

V

G

G

L

L

R

R

K

K

E

E

D

D

A

T

D

A

L

L

K

K

A

A

A

D

F

F

D

D

A

A

I

I

A

K

S

A

V

A

V

S

Q

E

D

D

G

G

T

T

L

I

A

K

R

T

I

L

A

S

A

L

K

K

Y

W

V

F

D

K

F

V

T

D

V

V

T

T

P

P

binding octopine: E11 (= E35), Y14 (= Y38), W52 (= W76), A69 (= A93), A70 (≠ T94), M71 (= M95), S72 (≠ N96), R77 (= R101), N92 (≠ A116), Q140 (= Q141), T143 (= T144), T144 (= T145), N183 (≠ T184)

P02911 Lysine/arginine/ornithine-binding periplasmic protein; LAO-binding protein from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
38% identity, 99% coverage: 1:257/259 of query aligns to 1:257/260 of P02911

query
sites
P02911

M

M

K

K

R

K

-

T

-

V

L

L

A

A

L

L

G

S

L

L

A

L

M

I

G

G

L

L

C

G

A

A

L

T

A

A

A

S

V

Y

P

A

T

A

A

L

S

P

R

Q

A

T

D

-

G

-

P

-

L

V

R

R

I

I

A

G

T

T

E
x
D

G

T

A

T

Y
|
Y

P

A

P

P

F

F

N

S

M

S

T

K

S

D

P

A

D

K

G

G

T

E

L

F

G

I

G

G

L

F

E
x
D

V

I

E

D

L

L

A

G

N

N

A

E

L

M

C
|
C

E

K

R

R

I

M

K

Q

R

V

R

K

C
|
C

T

T

L

W

V

V

A

A

Q

S

D

D

W
x
F

D

D

G

A

I

L

I

I

P

P

G

S

L

L

L

K

S

A

R

K

Y

I

D

D

A

A

I

I

M

I

A
x
S

T
x
S

M

L

N
x
S

I

I

T

T

P

D

E

K

R
|
R

A

Q

K

Q

A

E

I

I

A

A

F

F

S

S

A

D

P

K

Y

L

M

Y

V

A

P

D

A

S

Y

R

F

L

V

I

A

A

T

K

G

G

G

S

G

P

I

I

D

Q

G

P

T

T

E

L

A

E

T

S

L

L

A

K

G

G

K

K

S

H

V

V

G

G

A

V

Q
x
L

T

Q

S

G

T

S

T
|
T

H

Q

Y

E

R

A

Y

Y

V

A

E

N

K

D

H

N

F

W

-

R

G

T

K

K

T

G

V

V

S

D

L

V

K

V

N

A

Y

Y

D

A

T

N

A

Q

S

D

N

L

L

I

L

Y

A

S

D

D

L

L

K

T

S

A

G

G

R

R

I

L

D

D

A

A

I

L

T

Q

T
x
D

G

E

A

V

T

A

A

A

S

S

D

E

-

G

W

F

V

L

K

K

A

Q

D

P

A

A

S

G

K

K

S

E

L

Y

Q

A

L

F

V

A

G

G

K

P

P

S

L

V

V

K

D

D

A

K

E

K

V

Y

F

F

G

G

P

D

G

G

V

T

G

G

V

V

G

G

L

L

R

R

K

K

E

D

D

D

A

T

D

E

L

L

K

K

A

A

F

F

D

D

A

K

A

A

I

L

A

T

S

E

V

L

V

R

Q

Q

D

D

G

G

T

T

L

Y

A

D

R

K

I

M

A

A

A

K

K

K

Y

Y

V

F

D

D

F

F

T

N

V

V

D33 (≠ E35) binding ; binding ; binding ; mutation to A: Decreases arginine and histidine binding affinity.
Y36 (= Y38) mutation to A: Shows a drastic decrease in arginine and histidine binding affinity.
D52 (≠ E54) mutation to A: Shows a drastic decrease in arginine and histidine binding affinity.
C60 (= C62) modified: Disulfide link with 67
C67 (= C69) modified: Disulfide link with 60
F74 (≠ W76) mutation to A: Shows a drastic decrease in arginine and histidine binding affinity.
S91 (≠ A93) binding ; binding ; mutation to A: Has no effect on the arginine and histidine binding affinity.
S92 (≠ T94) binding ; binding ; binding ; mutation to A: Decreases arginine and histidine binding affinity.
S94 (≠ N96) binding ; binding ; binding ; mutation to A: Decreases arginine and histidine binding affinity.
R99 (= R101) binding ; binding ; binding ; mutation to A: Shows a drastic decrease in arginine and histidine binding affinity.
L139 (≠ Q141) mutation to K: Changes ligand specificity. Can bind glutamine. Still able to bind basic amino acids, however, with 1000-fold less affinity for arginine.; mutation to Q: Does not affect ligand preference.
T143 (= T145) binding ; binding ; binding
D183 (≠ T184) binding ; binding ; mutation to A: Shows a drastic decrease in arginine and histidine binding affinity.

5owfA Structure of a lao-binding protein mutant with glutamine (see paper)
38% identity, 88% coverage: 30:257/259 of query aligns to 3:232/235 of 5owfA

query
sites
5owfA

L

V

R

R

I

I

A

G

T

T

E

D

G

T

A

T

Y
|
Y

P

A

P

P

F

F

N

S

M

S

T

K

S

D

P

A

D

K

G

G

T

E

L

F

G

I

G

G

L

F

E

D

V

I

E

D

L

L

A

G

N

N

A

E

L

M

C

C

E

K

R

R

I

M

K

Q

R

V

R

K

C

C

T

T

L

W

V

V

A

A

Q

S

D

D

W
x
F

D

D

G

A

I

L

I

I

P

P

G

S

L

L

L

K

S

A

R

K

Y

I

D

D

A

A

I

I

M

I

A
x
S

T
x
S

M

L

N
x
S

I

I

T

T

P

D

E

K

R
|
R

A

Q

K

Q

A

E

I

I

A

A

F

F

S

S

A

D

P

K

Y

L

M

Y

V

A

P

D

A

S

Y

R

F

L

V

I

A

A

T

K

G

G

G

S

G

P

I

I

D

Q

G

P

T

T

E

L

A

E

T

S

L

L

A

K

G

G

K

K

S

H

V

V

G

G

A

V

Q
x
K

T

Q

S

G

T
x
S

T
|
T

H

Q

Y

E

R

A

Y

Y

V

A

E

N

K

D

H

N

F

W

-

R

G

T

K

K

T

G

V

V

S

D

L

V

K

V

N

A

Y

Y

D

A

T

N

A

Q

S

D

N

L

L

I

L

Y

A

S

D

D

L

L

K

T

S

A

G

G

R

R

I

L

D

D

A

A

I

L

T

Q

T
x
D

G

E

A

V

T

A

A

A

S

S

D

E

-

G

W

F

V

L

K

K

A

Q

D

P

A

A

S

G

K

K

S

E

L

Y

Q

A

L

F

V

A

G

G

K

P

P

S

L

V

V

K

D

D

A

K

E

K

V

Y

F

F

G

G

P

D

G

G

V

T

G

G

V

V

G

G

L

L

R

R

K

K

E

D

D

D

A

T

D

E

L

L

K

K

A

A

F

F

D

D

A

K

A

A

I

L

A

T

S

E

V

L

V

R

Q

Q

D

D

G

G

T

T

L

Y

A

D

R

K

I

M

A

A

A

K

K

K

Y

Y

V

F

D

D

F

F

T

N

V

V

binding glutamine: Y11 (= Y38), F49 (≠ W76), S66 (≠ A93), S67 (≠ T94), S69 (≠ N96), R74 (= R101), K114 (≠ Q141), S117 (≠ T144), T118 (= T145), D158 (≠ T184)

1lstA Three-dimensional structures of the periplasmic lysine-, arginine-, ornithine-binding protein with and without a ligand (see paper)
38% identity, 88% coverage: 30:257/259 of query aligns to 6:235/238 of 1lstA

query
sites
1lstA

L

V

R

R

I

I

A

G

T

T

E

D

G

T

A

T

Y
|
Y

P

A

P

P

F

F

N

S

M

S

T

K

S

D

P

A

D

K

G

G

T

E

L

F

G

I

G

G

L

F

E

D

V

I

E

D

L

L

A

G

N

N

A

E

L

M

C

C

E

K

R

R

I

M

K

Q

R

V

R

K

C

C

T

T

L

W

V

V

A

A

Q

S

D

D

W
x
F

D

D

G

A

I

L

I

I

P

P

G

S

L

L

L

K

S

A

R

K

Y

I

D

D

A

A

I

I

M

I

A

S

T
x
S

M

L

N
x
S

I

I

T

T

P

D

E

K

R
|
R

A

Q

K

Q

A

E

I

I

A

A

F

F

S

S

A

D

P

K

Y

L

M

Y

V

A

P

D

A

S

Y

R

F

L

V

I

A

A

T

K

G

G

G

S

G

P

I

I

D

Q

G

P

T

T

E

L

A

E

T

S

L

L

A

K

G

G

K

K

S

H

V

V

G

G

A

V

Q
x
L

T

Q

S

G

T
x
S

T
|
T

H
x
Q

Y

E

R

A

Y

Y

V

A

E

N

K

D

H

N

F

W

-

R

G

T

K

K

T

G

V

V

S

D

L

V

K

V

N

A

Y

Y

D

A

T

N

A

Q

S

D

N

L

L

I

L

Y

A

S

D

D

L

L

K

T

S

A

G

G

R

R

I

L

D

D

A

A

I

L

T

Q

T
x
D

G

E

A

V

T

A

A

A

S

S

D

E

-

G

W

F

V

L

K

K

A

Q

D

P

A

A

S

G

K

K

S

E

L

Y

Q

A

L

F

V

A

G

G

K

P

P

S

L

V

V

K

D

D

A

K

E

K

V

Y

F

F

G

G

P

D

G

G

V

T

G

G

V

V

G

G

L

L

R

R

K

K

E

D

D

D

A

T

D

E

L

L

K

K

A

A

F

F

D

D

A

K

A

A

I

L

A

T

S

E

V

L

V

R

Q

Q

D

D

G

G

T

T

L

Y

A

D

R

K

I

M

A

A

A

K

K

K

Y

Y

V

F

D

D

F

F

T

N

V

V

binding lysine: Y14 (= Y38), F52 (≠ W76), S70 (≠ T94), S72 (≠ N96), R77 (= R101), L117 (≠ Q141), S120 (≠ T144), T121 (= T145), Q122 (≠ H146), D161 (≠ T184)

1lahE Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein (see paper)
38% identity, 88% coverage: 30:257/259 of query aligns to 6:235/238 of 1lahE

query
sites
1lahE

L

V

R

R

I

I

A

G

T

T

E

D

G

T

A

T

Y
|
Y

P

A

P

P

F

F

N

S

M

S

T

K

S

D

P

A

D

K

G

G

T

E

L

F

G

I

G

G

L

F

E

D

V

I

E

D

L

L

A

G

N

N

A

E

L

M

C

C

E

K

R

R

I

M

K

Q

R

V

R

K

C

C

T

T

L

W

V

V

A

A

Q

S

D

D

W
x
F

D

D

G

A

I

L

I

I

P

P

G

S

L

L

L

K

S

A

R

K

Y

I

D

D

A

A

I

I

M

I

A

S

T
x
S

M

L

N
x
S

I

I

T

T

P

D

E

K

R
|
R

A

Q

K

Q

A

E

I

I

A

A

F

F

S

S

A

D

P

K

Y

L

M

Y

V

A

P

D

A

S

Y

R

F

L

V

I

A

A

T

K

G

G

G

S

G

P

I

I

D

Q

G

P

T

T

E

L

A

E

T

S

L

L

A

K

G

G

K

K

S

H

V

V

G

G

A

V

Q

L

T

Q

S

G

T
x
S

T

T

H
x
Q

Y

E

R

A

Y

Y

V

A

E

N

K

D

H

N

F

W

-

R

G

T

K

K

T

G

V

V

S

D

L

V

K

V

N

A

Y

Y

D

A

T

N

A

Q

S

D

N

L

L

I

L

Y

A

S

D

D

L

L

K

T

S

A

G

G

R

R

I

L

D

D

A

A

I

L

T

Q

T
x
D

G

E

A

V

T

A

A

A

S

S

D

E

-

G

W

F

V

L

K

K

A

Q

D

P

A

A

S

G

K

K

S

E

L

Y

Q

A

L

F

V

A

G

G

K

P

P

S

L

V

V

K

D

D

A

K

E

K

V

Y

F

F

G

G

P

D

G

G

V

T

G

G

V

V

G

G

L

L

R

R

K

K

E

D

D

D

A

T

D

E

L

L

K

K

A

A

F

F

D

D

A

K

A

A

I

L

A

T

S

E

V

L

V

R

Q

Q

D

D

G

G

T

T

L

Y

A

D

R

K

I

M

A

A

A

K

K

K

Y

Y

V

F

D

D

F

F

T

N

V

V

binding L-ornithine: Y14 (= Y38), F52 (≠ W76), S70 (≠ T94), S72 (≠ N96), R77 (= R101), S120 (≠ T144), Q122 (≠ H146), D161 (≠ T184)

1lagE Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein (see paper)
38% identity, 88% coverage: 30:257/259 of query aligns to 6:235/238 of 1lagE

query
sites
1lagE

L

V

R

R

I

I

A

G

T

T

E

D

G

T

A

T

Y
|
Y

P

A

P

P

F

F

N

S

M

S

T

K

S

D

P

A

D

K

G

G

T

E

L

F

G

I

G

G

L

F

E

D

V

I

E

D

L

L

A

G

N

N

A

E

L

M

C

C

E

K

R

R

I

M

K

Q

R

V

R

K

C

C

T

T

L

W

V

V

A

A

Q

S

D

D

W
x
F

D

D

G

A

I

L

I

I

P

P

G

S

L

L

L

K

S

A

R

K

Y

I

D

D

A

A

I

I

M

I

A
x
S

T
x
S

M
x
L

N
x
S

I

I

T

T

P

D

E

K

R
|
R

A

Q

K

Q

A

E

I

I

A

A

F

F

S

S

A

D

P

K

Y

L

M

Y

V

A

P

D

A

S

Y

R

F

L

V

I

A

A

T

K

G

G

G

S

G

P

I

I

D

Q

G

P

T

T

E

L

A

E

T

S

L

L

A

K

G

G

K

K

S

H

V

V

G

G

A

V

Q
x
L

T

Q

S

G

T
x
S

T

T

H
x
Q

Y

E

R

A

Y

Y

V

A

E

N

K

D

H

N

F

W

-

R

G

T

K

K

T

G

V

V

S

D

L

V

K

V

N

A

Y

Y

D

A

T

N

A

Q

S

D

N

L

L

I

L

Y

A

S

D

D

L

L

K

T

S

A

G

G

R

R

I

L

D

D

A

A

I

L

T

Q

T
x
D

G

E

A

V

T

A

A

A

S

S

D

E

-

G

W

F

V

L

K

K

A

Q

D

P

A

A

S

G

K

K

S

E

L

Y

Q

A

L

F

V

A

G

G

K

P

P

S

L

V

V

K

D

D

A

K

E

K

V

Y

F

F

G

G

P

D

G

G

V

T

G

G

V

V

G

G

L

L

R

R

K

K

E

D

D

D

A

T

D

E

L

L

K

K

A

A

F

F

D

D

A

K

A

A

I

L

A

T

S

E

V

L

V

R

Q

Q

D

D

G

G

T

T

L

Y

A

D

R

K

I

M

A

A

A

K

K

K

Y

Y

V

F

D

D

F

F

T

N

V

V

binding histidine: Y14 (= Y38), F52 (≠ W76), S69 (≠ A93), S70 (≠ T94), L71 (≠ M95), S72 (≠ N96), R77 (= R101), L117 (≠ Q141), S120 (≠ T144), Q122 (≠ H146), D161 (≠ T184)

1lafE Structural bases for multiple ligand specificity of the periplasmic lysine-, arginine-, ornithine-binding protein (see paper)
38% identity, 88% coverage: 30:257/259 of query aligns to 6:235/238 of 1lafE

query
sites
1lafE

L

V

R

R

I

I

A

G

T

T

E
x
D

G

T

A

T

Y
|
Y

P

A

P

P

F

F

N

S

M

S

T

K

S

D

P

A

D

K

G

G

T

E

L

F

G

I

G

G

L

F

E

D

V

I

E

D

L

L

A

G

N

N

A

E

L

M

C

C

E

K

R

R

I

M

K

Q

R

V

R

K

C

C

T

T

L

W

V

V

A

A

Q

S

D

D

W
x
F

D

D

G

A

I

L

I

I

P

P

G

S

L

L

L

K

S

A

R

K

Y

I

D

D

A

A

I

I

M

I

A
x
S

T
x
S

M

L

N
x
S

I

I

T

T

P

D

E

K

R
|
R

A

Q

K

Q

A

E

I

I

A

A

F

F

S

S

A

D

P

K

Y

L

M

Y

V

A

P

D

A

S

Y

R

F

L

V

I

A

A

T

K

G

G

G

S

G

P

I

I

D

Q

G

P

T

T

E

L

A

E

T

S

L

L

A

K

G

G

K

K

S

H

V

V

G

G

A

V

Q
x
L

T

Q

S

G

T
x
S

T
|
T

H
x
Q

Y

E

R

A

Y

Y

V

A

E

N

K

D

H

N

F

W

-

R

G

T

K

K

T

G

V

V

S

D

L

V

K

V

N

A

Y

Y

D

A

T

N

A

Q

S

D

N

L

L

I

L

Y

A

S

D

D

L

L

K

T

S

A

G

G

R

R

I

L

D

D

A

A

I

L

T

Q

T
x
D

G

E

A

V

T

A

A

A

S

S

D

E

-

G

W

F

V

L

K

K

A

Q

D

P

A

A

S

G

K

K

S

E

L

Y

Q

A

L

F

V

A

G

G

K

P

P

S

L

V

V

K

D

D

A

K

E

K

V

Y

F

F

G

G

P

D

G

G

V

T

G

G

V

V

G

G

L

L

R

R

K

K

E

D

D

D

A

T

D

E

L

L

K

K

A

A

F

F

D

D

A

K

A

A

I

L

A

T

S

E

V

L

V

R

Q

Q

D

D

G

G

T

T

L

Y

A

D

R

K

I

M

A

A

A

K

K

K

Y

Y

V

F

D

D

F

F

T

N

V

V

binding arginine: D11 (≠ E35), Y14 (= Y38), F52 (≠ W76), S69 (≠ A93), S70 (≠ T94), S72 (≠ N96), R77 (= R101), L117 (≠ Q141), S120 (≠ T144), T121 (= T145), Q122 (≠ H146), D161 (≠ T184)

8hqrA Crystal structure of the arginine-/lysine-binding protein sar11_1210 from 'candidatus pelagibacter ubique' htcc1062 bound to arginine
38% identity, 92% coverage: 19:255/259 of query aligns to 1:263/267 of 8hqrA

query
sites
8hqrA

V

V

P

P

T

R

A

G

S

S

R

H

A

M

D

D

G

-

P

-

P

K

L

I

R

K

I

I

A

G

T

T

E
|
E

G

G

A

A

Y
|
Y

P

P

F

W

N

N

M

S

T

K

S

D

P

A

D

S

G

G

T

A

L

L

G

I

G

G

L

F

E

E

V

V

E

E

L

L

A

A

N

E

A

E

L

L

C

C

E

K

R

I

I

M

K

G

R

R

R

E

C

C

T

T

L

I

V

V

A

E

Q

Q

D

D

W
|
W

D

D

G

G

I

M

I

I

P

P

G

A

L

L

S

M

R

R

R

K

Y

F

D

D

A

A

I

I

M

M

A
|
A

T
x
G

M

M

N
x
S

I

I

T

T

P

A

E

E

R
|
R

A

Q

K

K

A

T

I

I

A

T

F

F

S

S

A

Q

P

G

Y

Y

M

A

V

D

V
x
E

P

V

A

A

Y

A

F

L

V

A

A

V

A

M

T

K

G

G

G

S

I

L

D

E

G

S

T

M

E

D

-

T

-

P

-

E

-

G

-

I

-

N

-

L

-

T

-

L

-

G

-

S

-

A

-

V

-

K

-

T

-

L

-

K

-

T

-

L

-

T

A

A

T

A

L

L

A

A

G

G

K

K

S

T

V

V

G

C

A

T

Q
|
Q

T

T

S

G

T
|
T

T
x
I

H

H

Y

Q

R

N

Y

F

V

L

E

E

K

S

H

G

F

D

G

V

K

G

T

K

V

V

S

N

L

V

K

R

N

T

Y

Y

D

K

T

T

A

Q

S

D

N

E

L

V

L

N

A

L

D

D

L

L

K

T

S

S

G

G

R

R

I

C

D

D

A

V

A

A

I

L

T

A

G

A

A

V

T

A

A

F

S

T

D

D

W

Y

V

-

K

-

A

A

D

D

A

K

S

S

-

G

K

K

S

P

L

V

Q

V

L

L

V

V

G

G

K

-

P

P

L

T

V

F

D

S

A

G

E

G

V

A

F

F

G

G

P

N

G

G

V

V

G

G

V

V

G

G

L

I

R

R

K

Q

-

G

-

D

-

A

-

I

-

G

-

T

E

R

D

D

A

A

D

K

L

L

K

L

A

K

A

D

F

F

D

N

A

K

A

A

I

I

A

N

S

T

V

A

V

R

Q

K

D

Q

G

G

T

I

L

I

A

S

R

K

I

L

A

A

A

I

K

K

Y

H

V

F

D

G

F

F

binding arginine: E15 (= E35), Y18 (= Y38), W56 (= W76), A73 (= A93), G74 (≠ T94), S76 (≠ N96), R81 (= R101), E94 (≠ V114), Q143 (= Q141), T146 (= T144), I147 (≠ T145)

P02910 Histidine-binding periplasmic protein; HBP from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
37% identity, 88% coverage: 30:257/259 of query aligns to 28:257/260 of P02910

query
sites
P02910

L

I

R

R

I

I

A

G

T

T

E

D

G

P

A

T

Y

Y

P

A

P

P

F

F

N
x
E

M

S

T
x
K

S

N

P

A

D

Q

G

G

T
x
E

L

L

G

V

G

G

L

F

E

D

V

I

E

D

L

L

A

A

N

K

A

E

L

L

C

C

E

K

R

R

I

I

K

N

R

T

R

Q

C

C

T

T

L

F

V

V

A

E

Q

N

D

P

W

L

D

D

G

A

I

L

I

I

P

P

G

S

L

L

L

K

S

A

R

K

Y

I

D

D

A

A

I

I

M

M

A

S

T

S

M

L

N

S

I

I

T

T

P

E

E

K

R

R

A

Q

K

Q

A

E

I

I

A

A

F

F

S

T

A

D

P

K

Y

L

M

Y

V

A

P

D

A

S

Y

R

F

L

V

V

A

V

A

A

T

K

G

N

G

S

G

D

I

I

D

Q

G

P

T

T

E

V

A

A

T

S

L

L

A

K

G

G

K

K

S

R

V

V

G

G

A

V

Q

L

T

Q

S

G

T

T

H

Q

Y

E

R

T

Y

F

V

G

E

N

K

E

H

H

F

W

G

A

-

P

K

K

T

G

V

I

S

E

L

I

K

V

N

S

Y

Y

D

Q

T

G

A

Q

S

D

N

N

L

I

L

Y

A

S

D
|
D

L

L

K

T

S

A

G

G

R
|
R

I

I

D
|
D

A

A

I

F

T

Q

T

D

G

E

A

V

T

A

A

A

S

S

D

E

-

G

W

F

V

L

K

K

A

Q

D

P

A

V

S

G

K

K

S

D

L

Y

Q

K

L

F

V

G

G

G

K

P

P

A

L

V

V

K

D

D

A

E

E

K

V

L

F

F

G

G

P

V

G

G

V

T

G

G

V

M

G

G

L

L

R

R

K

K

E

E

D

D

A

N

D

E

L

L

K

R

A

E

A

A

F

L

D

N

A

K

A

A

I

F

A

A

S

E

V

M

V

R

Q

A

D

D

G

G

T

T

L

Y

A

E

R

K

I

L

A

A

A

K

K

K

Y

Y

V

F

D

D

F

F

T

D

V

V

E40 (≠ N42) mutation to K: Decrease in ATPase-inducing activity and histidine transport; when associated with K-47.
K42 (≠ T44) mutation to E: Increases ATPase-inducing activity and histidine transport; when associated with K-47.
E47 (≠ T49) mutation to K: Decrease in ATPase-inducing activity and histidine transport; when associated with K-40. Increases ATPase-inducing activity and histidine transport; when associated with E-42.
D171 (= D172) mutation D->A,N: Strong decrease in ATPase-inducing activity and histidine transport.
R176 (= R177) mutation R->D,S: Strong decrease in ATPase-inducing activity and histidine transport.
D178 (= D179) mutation to A: Slight decrease in ATPase-inducing activity and histidine transport.

Sites not aligning to the query:

1:22 signal peptide

1hslA Refined 1.89 angstroms structure of the histidine-binding protein complexed with histidine and its relationship with many other active transport(slash)chemosensory receptors (see paper)
37% identity, 88% coverage: 30:257/259 of query aligns to 6:235/238 of 1hslA

query
sites
1hslA

L

I

R

R

I

I

A

G

T

T

E

D

G

P

A

T

Y
|
Y

P

A

P

P

F

F

N

E

M

S

T

K

S

N

P

A

D

Q

G

G

T

E

L

L

G

V

G

G

L

F

E

D

V

I

E

D

L

L

A

A

N

K

A

E

L

L

C

C

E

K

R

R

I

I

K

N

R

T

R

Q

C

C

T

T

L

F

V

V

A

E

Q

N

D

P

W
x
L

D

D

G

A

I

L

I

I

P

P

G

S

L

L

L

K

S

A

R

K

Y

I

D

D

A

A

I

I

M

M

A
x
S

T
x
S

M
x
L

N
x
S

I

I

T

T

P

E

E

K

R
|
R

A

Q

K

Q

A

E

I

I

A

A

F

F

S

T

A

D

P

K

Y

L

M

Y

V

A

P

D

A

S

Y

R

F

L

V

V

A

V

A

A

T

K

G

N

G

S

G

D

I

I

D

Q

G

P

T

T

E

V

A

A

T

S

L

L

A

K

G

G

K

K

S

R

V

V

G

G

A

V

Q

L

T

Q

S

G

T
|
T

H

Q

Y

E

R

T

Y

F

V

G

E

N

K

E

H

H

F

W

G

A

-

P

K

K

T

G

V

I

S

E

L

I

K

V

N

S

Y

Y

D

Q

T

G

A

Q

S

D

N

N

L

I

L

Y

A

S

D

D

L

L

K

T

S

A

G

G

R

R

I

I

D

D

A

A

I

F

T

Q

T
x
D

G

E

A

V

T

A

A

A

S

S

D

E

-

G

W

F

V

L

K

K

A

Q

D

P

A

V

S

G

K

K

S

D

L

Y

Q

K

L

F

V

G

G

G

K

P

P

A

L

V

V

K

D

D

A

E

E

K

V

L

F

F

G

G

P

V

G

G

V

T

G

G

V

M

G

G

L

L

R

R

K

K

E

E

D

D

A

N

D

E

L

L

K

R

A

E

A

A

F

L

D

N

A

K

A

A

I

F

A

A

S

E

V

M

V

R

Q

A

D

D

G

G

T

T

L

Y

A

E

R

K

I

L

A

A

A

K

K

K

Y

Y

V

F

D

D

F

F

T

D

V

V

binding histidine: Y14 (= Y38), L52 (≠ W76), S69 (≠ A93), S70 (≠ T94), L71 (≠ M95), S72 (≠ N96), R77 (= R101), T120 (= T144), T121 (= T145), D161 (≠ T184)

P0AEU0 Histidine-binding periplasmic protein; HBP from Escherichia coli (strain K12) (see 3 papers)
37% identity, 88% coverage: 30:257/259 of query aligns to 28:257/260 of P0AEU0

query
sites
P0AEU0

L

I

R

R

I

I

A

G

T

T

E

D

G

P

A

T

Y

Y

P

A

P

P

F

F

N

E

M

S

T

K

S

N

P

S

D

Q

G

G

T

E

L

L

G

V

G

G

L

F

E

D

V

I

E

D

L

L

A

A

N

K

A

E

L

L

C
|
C

E

K

R

R

I

I

K

N

R

T

R

Q

C
|
C

T

T

L

F

V

V

A

E

Q

N

D

P

W

L

D

D

G

A

I

L

I

I

P

P

G

S

L

L

L

K

S

A

R

K

Y

I

D

D

A

A

I

I

M

M

A
x
S

T
x
S

M

L

N
x
S

I

I

T

T

P

E

E

K

R
|
R

A

Q

K

Q

A

E

I

I

A

A

F

F

S

T

A

D

P

K

Y

L

M

Y

V

A

P

D

A

S

Y

R

F

L

V

V

A

V

A

A

T

K

G

N

G

S

G

D

I

I

D

Q

G

P

T

T

E

V

A

E

T

S

L

L

A

K

G

G

K

K

S

R

V

V

G

G

A

V

Q

L

T

Q

S

G

T

T

T
|
T

H

Q

Y

E

R

T

Y

F

V

G

E

N

K

E

H

H

F

W

G

A

-

P

K

K

T

G

V

I

S

E

L

I

K

V

N

S

Y

Y

D

Q

T

G

A

Q

S

D

N

N

L

I

L

Y

A

S

D

D

L

L

K

T

S

A

G

G

R

R

I

I

D

D

A

A

I

F

T

Q

T
x
D

G

E

A

V

T

A

A

A

S

S

D

E

-

G

W

F

V

L

K

K

A

Q

D

P

A

V

S

G

K

K

S

D

L

Y

Q

K

L

F

V

G

G

G

K

P

P

S

L

V

V

K

D

D

A

E

E

K

V

L

F

F

G

G

P

V

G

G

V

T

G

G

V

M

G

G

L

L

R

R

K

K

E

E

D

D

A

N

D

E

L

L

K

R

A

E

A

A

F

L

D

N

A

K

A

A

I

F

A

A

S

E

V

M

V

R

Q

A

D

D

G

G

T

T

L

Y

A

E

R

K

I

L

A

A

A

K

K

K

Y

Y

V

F

D

D

F

F

T

D

V

V

C60 (= C62) modified: Disulfide link with 67
C67 (= C69) modified: Disulfide link with 60
S91 (≠ A93) binding
S92 (≠ T94) binding
S94 (≠ N96) binding
R99 (= R101) binding
T143 (= T145) binding
D183 (≠ T184) binding

Sites not aligning to the query:

1:22 signal peptide

3tqlA Structure of the amino acid abc transporter, periplasmic amino acid- binding protein from coxiella burnetii. (see paper)
32% identity, 86% coverage: 30:252/259 of query aligns to 4:224/225 of 3tqlA

query
sites
3tqlA

L

I

R

K

I

F

A

A

T

T

E
|
E

G

A

A

T

Y
|
Y

P

P

F

Y

N

V

M

Y

T

M

S

G

P

-

D

-

G

G

T

Q

L

V

G

E

G

G

L

F

E

G

V

A

E

D

L

I

A

V

N

K

A

A

L

V

C

C

E

K

R

Q

I

M

K

Q

R

A

R

V

C

C

T

T

L

I

V

S

A

N

Q

Q

D

P

W
|
W

D

D

G

S

I

L

I

I

P

P

G

S

L

L

L

K

S

L

R

G

R

K

Y

F

D

D

A

A

I

L

M

F

A
x
G

T
x
G

M

M

N
|
N

I

I

T

T

P

T

E

A

R
|
R

A

Q

K

K

A

E

I

V

A

D

F

F

S

T

A

D

P

P

Y

Y

M

Y

V

T

V

N

P

S

A

V

Y
x
S

F

F

V

I

A

A

A

D

T

K

G

N

G

T

G

P

I

L

D

T

G

L

T

S

E

K

A

Q

T

G

L

L

A

K

G

G

K

K

S

I

V

I

G

G

A

V

Q

Q

T

G

S

G

T

T

H

F

Y

D

R

S

Y

Y

V

L

E

Q

K

D

H

S

F

F

G

G

K

N

T

S

V

I

S

T

L

I

K

Q

N

R

Y

Y

D

P

T

S

A

E

S

E

N

D

L

A

L

L

A

M

D

D

L

L

K

T

S

S

G

G

R

R

I

V

D

D

A

A

A

V

I

V

T

G

T

D

G

T

A

P

T

L

A

I

S

K

D

Q

W

W

V

L

K

K

A

Q

D

N

A

G

S

R

K

R

S

E

L

Y

Q

V

L

L

V

I

G

G

K

K

P

P

L

V

V

N

D

D

A

P

E

N

V

Y

F

F

G

G

P

K

G

G

V

V

G

G

V

I

G

A

L

V

R

K

K

K

E

G

D

N

A

Q

D

A

L

L

K

L

A

L

A

K

F

L

D

N

A

K

A

A

I

L

A

A

S

A

V

I

V

K

Q

A

D

N

G

G

T

V

L

Y

A

A

R

A

I

I

A

V

A

Q

K

K

Y

Y

binding arginine: E9 (= E35), Y12 (= Y38), W48 (= W76), G65 (≠ A93), G66 (≠ T94), N68 (= N96), R73 (= R101), S89 (≠ Y117)

4zv1A An ancestral arginine-binding protein bound to arginine (see paper)
34% identity, 86% coverage: 30:252/259 of query aligns to 6:224/226 of 4zv1A

query
sites
4zv1A

L

L

R

R

I

V

A

G

T

T

E
|
E

G

A

A

T

Y
x
F

P

P

F

F

N

G

M

F

T

K

S

D

P

E

D

N

G

G

T

K

L

L

G

V

G

G

L

F

E

D

V

I

E

D

L

L

A

A

N

K

A

A

L

I

C

A

E

K

R

K

I

L

K

G

R

V

R

K

C

V

T

E

L

F

V

K

A

P

Q

M

D

D

W
x
F

D

D

G

G

I

I

P

P

G

A

L

L

L

Q

S

S

R

G

R

K

Y

I

D

D

A

V

I

V

M

I

A
|
A

T
x
G

M
|
M

N
x
T

I

I

T

T

P

E

E

E

R
|
R

A

K

K

K

A

Q

I

V

A

D

F

F

S

S

A

D

P

P

Y

Y

M

F

V

E

V

A

P

G

A

Q

Y

A

F

I

V

V

A

V

A

K

T

K

G

G

G

N

G

D

I

S

D

I

G

K

T

S

E

L

A

E

T

D

L

L

A

K

G

G

K

K

S

K

V

V

G

G

A

V

Q
|
Q

-

L

-

G

-
x
S

T
|
T

S

S

T

E

T

Q

H

H

Y

V

R

K

Y

K

V

V

E

A

K

K

H

D

F

A

G

G

K

-

T

-

V

V

S

K

L

V

K

K

N

K

Y

F

D

D

T

N

A

F

S

S

N

E

L

A

L

F

A

Q

D

E

L

L

K

K

S

S

G

G

R

R

I

V

D

D

A

A

A

V

I

V

T

T

T
x
D

G

N

A

A

T

V

A

A

S

L

D

A

W

Y

V

V

K

K

A

Q

D

N

A

P

S

N

K

A

S

G

L

V

Q

K

L

I

V

V

G

G

K

-

P

-

L

-

V

-

D

-

A

-

E

E

V

T

F

F

-

S

G

G

P

E

G

P

V

Y

G

G

V

I

G

A

L

V

R

R

K

K

E

G

D

N

A

S

D

E

L

L

K

L

A

E

A

K

F

I

D

N

A

K

A

A

I

L

A

E

S

E

V

M

V

K

Q

K

D

D

G

G

T

T

L

Y

A

D

R

K

I

I

A

Y

A

E

K

K

Y

W

binding arginine: E11 (= E35), F14 (≠ Y38), F52 (≠ W76), A69 (= A93), G70 (≠ T94), M71 (= M95), T72 (≠ N96), R77 (= R101), Q117 (= Q141), S120 (vs. gap), T121 (= T142), D161 (≠ T184)

4zv2A An ancestral arginine-binding protein bound to glutamine (see paper)
33% identity, 86% coverage: 30:252/259 of query aligns to 6:222/225 of 4zv2A

query
sites
4zv2A

L

L

R

R

I

V

A

G

T

T

E
|
E

G

A

A

T

Y
x
F

P

P

F

F

N

G

M

F

T

K

S

D

P

E

D

N

G

G

T

K

L

L

G

V

G

G

L

F

E

D

V

I

E

D

L

L

A

A

N

K

A

A

L

I

C

A

E

K

R

K

I

L

K

G

R

V

R

K

C

V

T

E

L

F

V

K

A

P

Q

M

D

D

W
x
F

D

D

G

G

I

I

P

P

G

A

L

L

L

Q

S

S

R

G

R

K

Y

I

D

D

A

V

I

V

M

I

A

A

T
x
G

M
|
M

N
x
T

I

I

T

T

P

E

E

E

R
|
R

A

K

K

K

A

Q

I

V

A

D

F

F

S

S

A

D

P

P

Y

Y

M

F

V

E

V

A

P

G

A

Q

Y

A

F

I

V

V

A

V

A

K

T

K

G

G

G

N

G

D

I

S

D

I

G

K

T

S

E

L

A

E

T

D

L

L

A

K

G

G

K

K

S

K

V

V

G

G

A

V

Q

Q

T

L

S

G

T
x
S

T
|
T

H

S

Y

E

R

Q

Y

H

V

V

E

K

K

K

H

-

F

V

G

A

K

A

T

G

V

V

S

K

L

V

K

K

N

K

Y

F

D

D

T

N

A

F

S

S

N

E

L

A

L

F

A

Q

D

E

L

L

K

K

S

S

G

G

R

R

I

V

D

D

A

A

A

V

I

V

T

T

T
x
D

G

N

A

A

T

V

A

A

S

L

D

A

W

Y

V

V

K

K

A

Q

D

N

A

P

S

N

K

A

S

G

L

V

Q

K

L

I

V

V

G

G

K

-

P

-

L

-

V

-

D

-

A

-

E

E

V

T

F

F

-

S

G

G

P

E

G

P

V

Y

G

G

V

I

G

A

L

V

R

R

K

K

E

G

D

N

A

S

D

E

L

L

K

L

A

E

A

K

F

I

D

N

A

K

A

A

I

L

A

E

S

E

V

M

V

K

Q

K

D

D

G

G

T

T

L

Y

A

D

R

K

I

I

A

Y

A

E

K

K

Y

W

binding glutamine: E11 (= E35), F14 (≠ Y38), F52 (≠ W76), G70 (≠ T94), M71 (= M95), T72 (≠ N96), R77 (= R101), S120 (≠ T144), T121 (= T145), D159 (≠ T184)

Query Sequence

>AZOBR_RS27130 AZOBR_RS27130 polyamine ABC transporter substrate-binding protein
MKRLALGLAMGLCALAAAVPTASRADGPPLRIATEGAYPPFNMTSPDGTLGGLEVELANA
LCERIKRRCTLVAQDWDGIIPGLLSRRYDAIMATMNITPERAKAIAFSAPYMVVPAYFVA
ATGGGIDGTEATLAGKSVGAQTSTTHYRYVEKHFGKTVSLKNYDTASNLLADLKSGRIDA
AITTGATASDWVKADASKSLQLVGKPLVDAEVFGPGVGVGLRKEDADLKAAFDAAIASVV
QDGTLARIAAKYVDFTVTP

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory