Comparing AZOBR_RS31030 FitnessBrowser__azobra:AZOBR_RS31030 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
8uw6B Acetylornithine deacetylase from escherichia coli, di-zinc form. (see paper)
33% identity, 91% coverage: 15:376/398 of query aligns to 4:360/381 of 8uw6B
Sites not aligning to the query:
5vo3A Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
26% identity, 95% coverage: 11:390/398 of query aligns to 3:374/380 of 5vo3A
P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 3 papers)
26% identity, 94% coverage: 16:390/398 of query aligns to 4:370/377 of P44514
7lgpB Dape enzyme from shigella flexneri
32% identity, 49% coverage: 78:271/398 of query aligns to 63:259/377 of 7lgpB
7uoiA Crystallographic structure of dape from enterococcus faecium (see paper)
25% identity, 92% coverage: 11:377/398 of query aligns to 4:364/383 of 7uoiA
7t1qA Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
31% identity, 52% coverage: 65:272/398 of query aligns to 50:259/377 of 7t1qA
Sites not aligning to the query:
4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril (see paper)
28% identity, 64% coverage: 16:271/398 of query aligns to 4:258/375 of 4pqaA
Sites not aligning to the query:
4o23A Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
28% identity, 64% coverage: 16:271/398 of query aligns to 4:258/376 of 4o23A
Q8P8J5 N-acetyl-L-citrulline deacetylase; ACDase; Acetylcitrulline deacetylase; EC 3.5.1.- from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see paper)
27% identity, 94% coverage: 17:390/398 of query aligns to 8:361/366 of Q8P8J5
2f7vA Structure of acetylcitrulline deacetylase complexed with one co (see paper)
26% identity, 94% coverage: 17:390/398 of query aligns to 9:356/360 of 2f7vA
4h2kA Crystal structure of the catalytic domain of succinyl-diaminopimelate desuccinylase from haemophilus influenzae (see paper)
33% identity, 43% coverage: 11:180/398 of query aligns to 1:170/258 of 4h2kA
Sites not aligning to the query:
3dljA Crystal structure of human carnosine dipeptidase 1
40% identity, 22% coverage: 75:160/398 of query aligns to 93:181/471 of 3dljA
Sites not aligning to the query:
Q96KN2 Beta-Ala-His dipeptidase; CNDP dipeptidase 1; Carnosine dipeptidase 1; Glutamate carboxypeptidase-like protein 2; Serum carnosinase; EC 3.4.13.20 from Homo sapiens (Human) (see 4 papers)
40% identity, 22% coverage: 75:160/398 of query aligns to 124:212/507 of Q96KN2
Sites not aligning to the query:
Q96KP4 Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; Glutamate carboxypeptidase-like protein 1; Peptidase A; Threonyl dipeptidase; EC 3.4.13.18 from Homo sapiens (Human)
42% identity, 20% coverage: 78:158/398 of query aligns to 94:177/475 of Q96KP4
Sites not aligning to the query:
2zogA Crystal structure of mouse carnosinase cn2 complexed with zn and bestatin (see paper)
40% identity, 20% coverage: 78:158/398 of query aligns to 98:181/478 of 2zogA
Sites not aligning to the query:
2zofA Crystal structure of mouse carnosinase cn2 complexed with mn and bestatin (see paper)
40% identity, 20% coverage: 78:158/398 of query aligns to 98:181/478 of 2zofA
Sites not aligning to the query:
Q9D1A2 Cytosolic non-specific dipeptidase; CNDP dipeptidase 2; Glutamate carboxypeptidase-like protein 1; Threonyl dipeptidase; EC 3.4.13.18 from Mus musculus (Mouse) (see 2 papers)
40% identity, 20% coverage: 78:158/398 of query aligns to 94:177/475 of Q9D1A2
Sites not aligning to the query:
3pfoA Crystal structure of a putative acetylornithine deacetylase (rpa2325) from rhodopseudomonas palustris cga009 at 1.90 a resolution
29% identity, 44% coverage: 78:254/398 of query aligns to 99:276/426 of 3pfoA
Sites not aligning to the query:
4mmoA The crystal structure of a m20 family metallo-carboxypeptidase sso-cp2 from sulfolobus solfataricus
27% identity, 49% coverage: 40:236/398 of query aligns to 29:232/437 of 4mmoA
P37111 Aminoacylase-1; ACY-1; N-acyl-L-amino-acid amidohydrolase; EC 3.5.1.14 from Sus scrofa (Pig) (see paper)
29% identity, 56% coverage: 78:298/398 of query aligns to 75:295/407 of P37111
Sites not aligning to the query:
>AZOBR_RS31030 FitnessBrowser__azobra:AZOBR_RS31030
MMPSPDPAGPSACSPRTLELLRDLIAFDTTSRNSNLDLIHYIRDHLAELGVSSTLVFNEE
RTKANLYATIGPMDRGGVCLSGHTDVVPVDDQDWSSDPFTLTERDGKLFGRGTADMKGFI
AAALAMAPDFLAANLTTPVHYAFSYDEELGCLGVPGLLTQLAGMAVKPRLCIVGEPTRMR
VIVGHKGKVALRCRVHGHACHSSLAPQGVNAVEYAAELVSFLRGMGRRFAEQGPFDHDYD
IPYTTVHTGVMEGGTARNIVPSDASFEFEIRHLADHPVAPMLKELRDFAKTLEPEMRAVR
PDAGFSWETLSDSPALDTPPESEEVTLVKNLAEQNGHGKVAFGTEGALFTSIANIPAVVC
GPGDIEQAHKPDEYVELSELARAERFLHRLRDAAKKGL
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory