Comparing AZOBR_RS31275 FitnessBrowser__azobra:AZOBR_RS31275 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 6 hits to proteins with known functional sites (download)
4im7A Crystal structure of fructuronate reductase (ydfi) from e. Coli cft073 (efi target efi-506389) complexed with nadh and d-mannonate
28% identity, 79% coverage: 73:470/501 of query aligns to 66:451/483 of 4im7A
Sites not aligning to the query:
7rk5B Mannitol-2-dehydrogenase bound to nadh from aspergillus fumigatus
26% identity, 88% coverage: 29:470/501 of query aligns to 36:468/501 of 7rk5B
1m2wA Pseudomonas fluorescens mannitol 2-dehydrogenase ternary complex with NAD and d-mannitol (see paper)
27% identity, 71% coverage: 29:386/501 of query aligns to 29:391/492 of 1m2wA
1lj8A Crystal structure of mannitol dehydrogenase in complex with NAD (see paper)
27% identity, 71% coverage: 29:386/501 of query aligns to 29:391/492 of 1lj8A
P09424 Mannitol-1-phosphate 5-dehydrogenase; EC 1.1.1.17 from Escherichia coli (strain K12) (see paper)
24% identity, 67% coverage: 30:366/501 of query aligns to 4:290/382 of P09424
Q4X1A4 Mannitol-1-phosphate 5-dehydrogenase; M1PDH; MPD; MPDH; EC 1.1.1.17 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see paper)
25% identity, 39% coverage: 217:409/501 of query aligns to 154:335/388 of Q4X1A4
>AZOBR_RS31275 FitnessBrowser__azobra:AZOBR_RS31275
MPLLSRESLAAGAFDVAHTAGAPRLPVTILQIGDGNFLRGFVDWMVDVANGAGLMSAGVA
IAQPLDQGVAGLLNAQEGLYTVLLRGIEQGKEVESRRVVSCVSDALNPYAEWDRMLALAT
SPALRFLVSNTTEAGIADVAEPYTPGACQQSFPAKVAALLHARFTALGGTPDSGLVLLPC
ELIEANGAKLKRIVLAHAKRWGLESGFAAWVEAHNHFLNTLVDRIVPGYPRDEAEALAAT
WGYEDPLAVTGEPFHVWVIEGPAALAEEFPLHKAGLNVVWTDDLKPYRTRKVRILNGAHT
ASALAAFVAGVDTVKGMMDDATLSAYLNTVMFGEIVPFVPLPDAERQDYARTIMERFGNP
YIRHELIAIALNSVSKWQVRVLPSLKDYAAAHGEAPDGLSFSLAALLRFYKGTLAADGAC
TGTRDAGPYPIRDDAAVLTALSGAWAAHGGDPAALVDAVLSNAALWGEDLTRIPGLAHRT
AVHLAVIEERGMRGALEALVS
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory