SitesBLAST

SitesBLAST – Find functional sites

SitesBLAST

Comparing AZOBR_RS32405 AZOBR_RS32405 ABC transporter to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 20 (the maximum) hits to proteins with known functional sites (download)

1g9xB Characterization of the twinning structure of mj1267, an atp-binding cassette of an abc transporter (see paper)
33% identity, 96% coverage: 5:249/255 of query aligns to 4:253/253 of 1g9xB

query
sites
1g9xB

L

I

L

L

S

R

I

T

Q

E

G

N

L

I

T

V

R

K

R

Y

F
|
F

G

G

G

E

L
x
F

L

K

A

A

V

L

S

D

D

G

V

V

S

S

A

I

T

S

I

V

A

C

K

K

G

G

E

D

L

V

V

T

G

L

L

I

I

I

G

G

P

P

N
|
N

G
|
G

A
x
S

G
|
G

K
|
K

T
x
S

T
|
T

L

L

F

I

N

N

L

V

I

I

T

T

G

G

F

F

T

L

P

K

P

A

S

D

D

E

G

G

T

R

V

V

T

Y

F

F

D

E

G

N

Q

K

D

D

V

I

T

T

G

N

R

K

K

E

P

P

W

A

Q

E

I

L

A

Y

R

H

M

Y

G

G

M

I

G

V

R

R

T

T

F

F

Q

Q

N

T

L

P

R

Q

V

P

F

L

P

K

N

E

M

M

T

T

V

V

F

L

D

E

N

N

V

L

S

L

V

I

G

G

A

E

V

I

G

N

A

P

F

-

G

G

Q

E

S

S

P

P

W

L

R

N

A

S

L

L

I

F

N

Y

G

K

G

K

-

W

-

I

A

P

H

K

S

E

R

E

A

E

V

M

S

V

E

E

R

K

S

A

W

F

E

K

A

I

L

L

E

E

R

F

V

L

G

K

L

L

T

S

A

H

Q

L

A

Y

G

D

D

R

I

K

A

A

A

G

N

E

L

L

S

S

Y

G

G

G

K

Q

R

M

K

K

Y

L

L

V

E

E

I

I

A

G

R

R

A

A

L

L

A

M

T

T

A

N

P

P

R

K

L

M

L

I

I

V

L

M

D

D

E
|
E

P

P

A

I

A

A

G

G

L

V

N

A

D

P

T

G

E

L

T

A

A

H

E

D

L

I

A

F

D

N

F

H

I

V

R

L

R

E

L

L

H

K

A

A

G

K

G

G

V

I

T

T

V

F

L

L

L

I

V

I

E

E

H

H

D

R

M

L

G

D

L

I

V

V

M

L

G

N

S

Y

C

I

S

D

R

H

V

L

I

Y

V

V

L

M

A

F

S

N

G

G

R

Q

K

I

I

I

A

A

D

E

G

G

T

R

P

G

E

E

A

E

-

E

-

I

-

K

-

N

V

V

Q

L

R

S

D

D

P

P

A

K

V

V

L

V

E

E

A

I

Y

Y

L

I

G

G

binding adenosine-5'-diphosphate: F14 (= F15), F17 (≠ L18), N39 (= N40), G40 (= G41), S41 (≠ A42), G42 (= G43), K43 (= K44), S44 (≠ T45), T45 (= T46)
binding magnesium ion: S44 (≠ T45), E176 (= E176)

1g6hA Crystal structure of the adp conformation of mj1267, an atp- binding cassette of an abc transporter (see paper)
33% identity, 96% coverage: 5:249/255 of query aligns to 4:253/254 of 1g6hA

query
sites
1g6hA

L

I

L

L

S

R

I

T

Q

E

G

N

L

I

T

V

R

K

R

Y

F
|
F

G

G

G

E

L
x
F

L

K

A

A

V

L

S

D

D

G

V

V

S

S

A

I

T

S

I

V

A

N

K

K

G

G

E

D

L

V

V

T

G

L

L

I

I

I

G

G

P

P

N
|
N

G
|
G

A
x
S

G
|
G

K
|
K

T
x
S

T
|
T

L

L

F

I

N

N

L

V

I

I

T

T

G

G

F

F

T

L

P

K

P

A

S

D

D

E

G

G

T

R

V

V

T

Y

F

F

D

E

G

N

Q

K

D

D

V

I

T

T

G

N

R

K

K

E

P

P

W

A

Q

E

I

L

A

Y

R

H

M

Y

G

G

M

I

G

V

R

R

T

T

F

F

Q

Q

N

T

L

P

R

Q

V

P

F

L

P

K

N

E

M

M

T

T

V

V

F

L

D

E

N

N

V

L

S

L

V

I

G

G

A

E

V

I

G

C

A

P

F

-

G

G

Q

E

S

S

P

P

W

L

R

N

A

S

L

L

I

F

N

Y

G

K

G

K

-

W

-

I

A

P

H

K

S

E

R

E

A

E

V

M

S

V

E

E

R

K

S

A

W

F

E

K

A

I

L

L

E

E

R

F

V

L

G

K

L

L

T

S

A

H

Q

L

A

Y

G

D

D

R

I

K

A

A

A

G

N

E

L

L

S

S

Y

G

G

G

K

Q

R

M

K

K

Y

L

L

V

E

E

I

I

A

G

R

R

A

A

L

L

A

M

T

T

A

N

P

P

R

K

L

M

L

I

I

V

L

M

D

D

E

E

P

P

A

I

A

A

G

G

L

V

N

A

D

P

T

G

E

L

T

A

A

H

E

D

L

I

A

F

D

N

F

H

I

V

R

L

R

E

L

L

H

K

A

A

G

K

G

G

V

I

T

T

V

F

L

L

L

I

V

I

E

E

H

H

D

R

M

L

G

D

L

I

V

V

M

L

G

N

S

Y

C

I

S

D

R

H

V

L

I

Y

V

V

L

M

A

F

S

N

G

G

R

Q

K

I

I

I

A

A

D

E

G

G

T

R

P

G

E

E

A

E

-

E

-

I

-

K

-

N

V

V

Q

L

R

S

D

D

P

P

A

K

V

V

L

V

E

E

A

I

Y

Y

L

I

G

G

binding adenosine-5'-diphosphate: F14 (= F15), F17 (≠ L18), N39 (= N40), G40 (= G41), S41 (≠ A42), G42 (= G43), K43 (= K44), S44 (≠ T45), T45 (= T46)

4u00A Crystal structure of ttha1159 in complex with adp (see paper)
33% identity, 91% coverage: 5:237/255 of query aligns to 2:223/241 of 4u00A

query
sites
4u00A

L

I

L

I

S

R

I

I

Q

R

G

N

L

L

T

H

R

K

R

W

F
|
F

G

G

G

P

L
|
L

L

H

A
x
V

V

L

S

K

D

G

V

I

S

H

A

L

T

E

I

V

A

A

K

P

G

G

E

E

L

K

V

L

G

V

L

I

I

I

G

G

P

P

N
x
S

G
|
G

A
x
S

G
|
G

K
|
K

T
x
S

T
|
T

L

L

F

I

N

R

L

T

I

I

T

N

G

R

F

L

T

E

P

D

P

F

S

Q

D

E

G

G

T

E

V

V

T

V

F

V

D

D

G

G

Q

L

D

S

V

V

T

K

G

D

R

D

K

R

P

A

W

L

Q

R

I

E

A

I

R

R

M

R

G

E

M

V

G

G

R

M

T

V

F

F

Q

Q

N

Q

L

F

R

N

V

L

F

F

P

P

N

H

M

M

T

T

V

V

F

L

D

E

N

N

V

V

S

T

V

L

G

-

A

-

V

-

G

-

A

-

F

-

G

-

Q

-

S

A

P

P

W

M

R

R

A

-

L

-

I

V

N

R

G

R

G

W

A

P

H

R

S

E

R

K

A

A

V

-

S

E

E

K

R

K

S

A

W

L

E

E

A

L

L

L

E

E

R

R

V

V

G

G

L

I

T

L

A

D

Q

Q

A

A

G

R

D

K

I

Y

A

P

A

A

N

Q

L

L

S

S

Y

G

G

G

K

Q

R

Q

K

Q

Y

R

L

V

E

A

I

I

A

A

R

R

A

A

L

L

A

A

T

M

A

E

P

P

R

K

L

I

L

M

I

L

L

F

D

D

E

E

P

P

A

T

A

S

G

A

L

L

N

D

D

P

T

E

E

M

T

V

A

G

E

E

L

V

A

L

D

D

F

V

I

M

R

R

R

D

L

L

H

A

A

Q

G

G

G

G

V

M

T

T

V

M

L

V

L

V

V

V

E

T

H

H

D

E

M

M

G

G

L

F

V

A

M

R

G

E

S

V

C

A

S

D

R

R

V

V

I

V

V

F

L

M

A

D

S

G

G

G

R

Q

K

I

I

V

A

E

D

E

G

G

T

R

P

P

E

E

A

E

V

I

binding adenosine-5'-diphosphate: F12 (= F15), L15 (= L18), V17 (≠ A20), S37 (≠ N40), G38 (= G41), S39 (≠ A42), G40 (= G43), K41 (= K44), S42 (≠ T45), T43 (= T46)

6s8nB Cryo-em structure of lptb2fgc in complex with lipopolysaccharide (see paper)
33% identity, 96% coverage: 6:249/255 of query aligns to 3:235/238 of 6s8nB

query
sites
6s8nB

L

L

S

T

I

A

Q

K

G

N

L

L

T

A

R

K

R

A

F

Y

G

K

G

G

L

R

L

R

A

V

V

V

S

E

D

D

V

V

S

S

A

L

T

T

I

V

A

N

K

S

G

G

E

E

L

I

V

V

G

G

L

L

I

L

G

G

P

P

N

N

G

G

A

A

G

G

K

K

T

T

T

T

L

T

F

F

N

Y

L

M

I

V

T

V

G

G

F

I

T

V

P

P

P

R

S

D

D

A

G

G

T

N

V

I

T

I

F

I

D

D

G

D

Q

D

D

D

V

I

T

S

G

L

R

L

K

P

P

L

W

H

Q

A

I

R

A

A

R

R

M

R

G

G

M

I

G

G

R

Y

T

L

F

P

Q

Q

N

E

L

A

R

S

V

I

F

F

P
x
R

N

R

M

L

T

S

V

V

F

Y

D

D

N

N

V

L

S

M

V

-

G

-

A

-

V

-

G

-

A

A

F

V

G

L

Q

Q

S

-

P

-

W

-

R

-

A

-

L

-

I

I

N

R

G

D

G

D

A

L

H

S

S

A

R

E

A

Q

V

R

S

E

E

D

R

R

S

A

W

N

E

E

A

L

L

M

E

E

R

E

V

F

G

H

L

I

T

E

A

H

Q

L

A

R

G

D

D

S

I
x
M

A
x
G

A
x
Q

N

S

L

L

S

S

Y

G

G

G

K

E

R

R

K

R

Y

R

L

V

E

E

I

I

A

A

R

R

A

A

L

L

A

A

T

A

A

N

P

P

R

K

L

F

L

I

I

L

L

L

D

D

E

E

P

P

A

F

A

A

G

G

L

V

N

D

D

P

T

I

E

S

T

V

A

I

E

D

L

I

A

K

D

R

F

I

I

I

R

E

R

H

L

L

H

R

A

D

G

S

G

G

V

L

T

G

V

V

L

L

L

I

V

T

E

D

H

H

D

N

M

V

G

R

L

E

V

T

M

L

G

A

S

V

C

C

S

E

R

R

V

A

I

Y

V

I

L

V

A

S

S

Q

G

G

R

H

K

L

I

I

A

A

D

H

G

G

T

T

P

P

E

T

A

E

V

I

Q

L

R

Q

D

D

P

E

A

H

V

V

L

K

E

R

A

V

Y

Y

L

L

G

G

binding 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione: R90 (≠ P93), M133 (≠ I147), G134 (≠ A148), Q135 (≠ A149)

6s8gA Cryo-em structure of lptb2fgc in complex with amp-pnp (see paper)
33% identity, 96% coverage: 6:249/255 of query aligns to 3:235/238 of 6s8gA

query
sites
6s8gA

L

L

S

T

I

A

Q

K

G

N

L

L

T

A

R

K

R

A

F
x
Y

G

K

G

G

L
x
R

L

R

A
x
V

V

V

S

E

D

D

V

V

S

S

A

L

T

T

I

V

A

N

K

S

G

G

E

E

L

I

V

V

G

G

L

L

I

L

G

G

P

P

N
|
N

G
|
G

A

A

G
|
G

K
|
K

T
|
T

T
|
T

L

T

F

F

N

Y

L

M

I

V

T

V

G

G

F

I

T

V

P

P

P

R

S

D

D

A

G

G

T

N

V

I

T

I

F

I

D

D

G

D

Q

D

D

D

V

I

T

S

G

L

R

L

K

P

P

L

W

H

Q

A

I

R

A

A

R

R

M

R

G

G

M

I

G

G

R

Y

T

L

F

P

Q
|
Q

N

E

L

A

R

S

V

I

F

F

P

R

N

R

M

L

T

S

V

V

F

Y

D

D

N

N

V

L

S

M

V

-

G

-

A

-

V

-

G

-

A

A

F

V

G

L

Q

Q

S

-

P

-

W

-

R

-

A

-

L

-

I

I

N

R

G

D

G

D

A

L

H

S

S

A

R

E

A

Q

V

R

S

E

E

D

R

R

S

A

W

N

E

E

A

L

L

M

E

E

R

E

V

F

G

H

L

I

T

E

A

H

Q

L

A

R

G

D

D

S

I

M

A

G

A

Q

N
x
S

L

L

S
|
S

Y

G

G

G

K
x
E

R

R

K

R

Y

R

L

V

E

E

I

I

A

A

R

R

A

A

L

L

A

A

T

A

A

N

P

P

R

K

L

F

L

I

I

L

L

L

D

D

E

E

P

P

A

F

A

A

G

G

L

V

N

D

D

P

T

I

E

S

T

V

A

I

E

D

L

I

A

K

D

R

F

I

I

I

R

E

R

H

L

L

H

R

A

D

G

S

G

G

V

L

T

G

V

V

L

L

L

I

V

T

E

D

H
|
H

D

N

M

V

G

R

L

E

V

T

M

L

G

A

S

V

C

C

S

E

R

R

V

A

I

Y

V

I

L

V

A

S

S

Q

G

G

R

H

K

L

I

I

A

A

D

H

G

G

T

T

P

P

E

T

A

E

V

I

Q

L

R

Q

D

D

P

E

A

H

V

V

L

K

E

R

A

V

Y

Y

L

L

G

G

binding phosphoaminophosphonic acid-adenylate ester: Y12 (≠ F15), R15 (≠ L18), V17 (≠ A20), N37 (= N40), G38 (= G41), G40 (= G43), K41 (= K44), T42 (= T45), T43 (= T46), Q84 (= Q87), S136 (≠ N150), S138 (= S152), E141 (≠ K155), H194 (= H208)

6mhzA Vanadate trapped cryo-em structure of e.Coli lptb2fg transporter (see paper)
33% identity, 96% coverage: 6:249/255 of query aligns to 3:235/235 of 6mhzA

query
sites
6mhzA

L

L

S

T

I

A

Q

K

G

N

L

L

T

A

R

K

R

A

F
x
Y

G

K

G

G

L

R

L

R

A

V

V

V

S

E

D

D

V

V

S

S

A

L

T

T

I

V

A

N

K

S

G

G

E

E

L

I

V

V

G

G

L

L

I

L

G

G

P
|
P

N
|
N

G
|
G

A
|
A

G
|
G

K
|
K

T
|
T

T
|
T

L

T

F

F

N

Y

L

M

I

V

T

V

G

G

F

I

T

V

P

P

P

R

S

D

D

A

G

G

T

N

V

I

T

I

F

I

D

D

G

D

Q

D

D

D

V

I

T

S

G

L

R

L

K

P

P

L

W

H

Q

A

I

R

A

A

R

R

M

R

G

G

M

I

G

G

R

Y

T

L

F

P

Q
|
Q

N

E

L

A

R

S

V

I

F

F

P

R

N

R

M

L

T

S

V

V

F

Y

D

D

N

N

V

L

S

M

V

-

G

-

A

-

V

-

G

-

A

A

F

V

G

L

Q

Q

S

-

P

-

W

-

R

-

A

-

L

-

I

I

N

R

G

D

G

D

A

L

H

S

S

A

R

E

A

Q

V

R

S

E

E

D

R

R

S

A

W

N

E

E

A

L

L

M

E

E

R

E

V

F

G

H

L

I

T

E

A

H

Q

L

A

R

G

D

D

S

I

M

A

G

A

Q

N
x
S

L

L

S
|
S

Y
x
G

G
|
G

K
x
E

R

R

K

R

Y

R

L

V

E

E

I

I

A

A

R

R

A

A

L

L

A

A

T

A

A

N

P

P

R

K

L

F

L

I

I

L

L

L

D

D

E
|
E

P

P

A

F

A

A

G
|
G

L

V

N

D

D

P

T

I

E

S

T

V

A

I

E

D

L

I

A

K

D

R

F

I

I

I

R

E

R

H

L

L

H

R

A

D

G

S

G

G

V

L

T

G

V

V

L

L

L

I

V

T

E

D

H
|
H

D

N

M

V

G

R

L

E

V

T

M

L

G

A

S

V

C

C

S

E

R

R

V

A

I

Y

V

I

L

V

A

S

S

Q

G

G

R

H

K

L

I

I

A

A

D

H

G

G

T

T

P

P

E

T

A

E

V

I

Q

L

R

Q

D

D

P

E

A

H

V

V

L

K

E

R

A

V

Y

Y

L

L

G

G

binding adp orthovanadate: Y12 (≠ F15), P36 (= P39), N37 (= N40), G38 (= G41), A39 (= A42), G40 (= G43), K41 (= K44), T42 (= T45), T43 (= T46), Q84 (= Q87), S136 (≠ N150), S138 (= S152), G139 (≠ Y153), G140 (= G154), E141 (≠ K155), E162 (= E176), G166 (= G180), H194 (= H208)

6mbnA Lptb e163q in complex with atp (see paper)
32% identity, 96% coverage: 6:249/255 of query aligns to 4:236/241 of 6mbnA

query
sites
6mbnA

L

L

S

T

I

A

Q

K

G

N

L

L

T

A

R

K

R

A

F
x
Y

G

K

G

G

L
x
R

L

R

A
x
V

V

V

S

E

D

D

V

V

S

S

A

L

T

T

I

V

A

N

K

S

G

G

E

E

L

I

V

V

G

G

L

L

I

L

G

G

P
|
P

N
|
N

G
|
G

A
|
A

G
|
G

K
|
K

T
|
T

T
|
T

L

T

F

F

N

Y

L

M

I

V

T

V

G

G

F

I

T

V

P

P

P

R

S

D

D

A

G

G

T

N

V

I

T

I

F

I

D

D

G

D

Q

D

D

D

V

I

T

S

G

L

R

L

K

P

P

L

W

H

Q

A

I

R

A

A

R

R

M

R

G

G

M

I

G

G

R

Y

T

L

F

P

Q
|
Q

N

E

L

A

R

S

V

I

F

F

P

R

N

R

M

L

T

S

V

V

F

Y

D

D

N

N

V

L

S

M

V

-

G

-

A

-

V

-

G

-

A

A

F

V

G

L

Q

Q

S

-

P

-

W

-

R

-

A

-

L

-

I

I

N

R

G

D

G

D

A

L

H

S

S

A

R

E

A

Q

V

R

S

E

E

D

R

R

S

A

W

N

E

E

A

L

L

M

E

E

R

E

V

F

G

H

L

I

T

E

A

H

Q

L

A

R

G

D

D

S

I

M

A

G

A

Q

N

S

L

L

S

S

Y

G

G

G

K

E

R

R

K

R

Y

R

L

V

E

E

I

I

A

A

R

R

A

A

L

L

A

A

T

A

A

N

P

P

R

K

L

F

L

I

I

L

L

L

D

D

E

Q

P

P

A

F

A

A

G

G

L

V

N

D

D

P

T

I

E

S

T

V

A

I

E

D

L

I

A

K

D

R

F

I

I

I

R

E

R

H

L

L

H

R

A

D

G

S

G

G

V

L

T

G

V

V

L

L

L

I

V

T

E

D

H
|
H

D

N

M

V

G

R

L

E

V

T

M

L

G

A

S

V

C

C

S

E

R

R

V

A

I

Y

V

I

L

V

A

S

S

Q

G

G

R

H

K

L

I

I

A

A

D

H

G

G

T

T

P

P

E

T

A

E

V

I

Q

L

R

Q

D

D

P

E

A

H

V

V

L

K

E

R

A

V

Y

Y

L

L

G

G

binding adenosine-5'-triphosphate: Y13 (≠ F15), R16 (≠ L18), V18 (≠ A20), P37 (= P39), N38 (= N40), G39 (= G41), A40 (= A42), G41 (= G43), K42 (= K44), T43 (= T45), T44 (= T46), Q85 (= Q87), H195 (= H208)

6b89A E. Coli lptb in complex with adp and novobiocin (see paper)
33% identity, 95% coverage: 6:248/255 of query aligns to 3:234/234 of 6b89A

query
sites
6b89A

L

L

S

T

I

A

Q

K

G

N

L

L

T

A

R

K

R

A

F
x
Y

G

K

G

G

L
x
R

L

R

A
x
V

V

V

S

E

D

D

V

V

S

S

A

L

T

T

I

V

A

N

K

S

G

G

E

E

L

I

V

V

G

G

L

L

I

L

G

G

P

P

N
|
N

G
|
G

A
|
A

G
|
G

K
|
K

T
|
T

T
|
T

L

T

F

F

N

Y

L

M

I

V

T

V

G

G

F

I

T

V

P

P

P

R

S

D

D

A

G

G

T

N

V

I

T

I

F

I

D

D

G

D

Q

D

D

D

V

I

T

S

G

L

R

L

K

P

P
x
L

W
x
H

Q

A

I

R

A

A

R

R

M

R

G

G

M

I

G

G

R
x
Y

T

L

F
x
P

Q
|
Q

N
x
E

L
x
A

R
x
S

V

I

F
|
F

P
x
R

N
x
R

M
x
L

T

S

V

V

F

Y

D

D

N

N

V

L

S

M

V

-

G

-

A

-

V

-

G

-

A

A

F
x
V

G

L

Q

Q

S

-

P

-

W

-

R

-

A

-

L

-

I

I

N

R

G

D

G

D

A

L

H

S

S

A

R

E

A

Q

V

R

S

E

E

D

R

R

S

A

W

N

E

E

A

L

L

M

E

E

R

E

V

F

G

H

L

I

T

E

A

H

Q

L

A

R

G

D

D

S

I

M

A

G

A
x
Q

N

S

L

L

S

S

Y

G

G

G

K

E

R

R

K

R

Y

R

L

V

E

E

I

I

A

A

R
|
R

A

A

L

L

A

A

T

A

A

N

P

P

R

K

L

F

L

I

I

L

L

L

D

D

E

E

P

P

A

F

A

A

G

G

L

V

N

D

D

P

T

I

E

S

T

V

A

I

E

D

L

I

A

K

D

R

F

I

I

I

R

E

R

H

L

L

H

R

A

D

G

S

G

G

V

L

T

G

V

V

L

L

L

I

V

T

E

D

H

H

D

N

M

V

G

R

L

E

V

T

M

L

G

A

S

V

C

C

S

E

R

R

V

A

I

Y

V

I

L

V

A

S

S

Q

G

G

R

H

K

L

I

I

A

A

D

H

G

G

T

T

P

P

E

T

A

E

V

I

Q

L

R

Q

D

D

P

E

A

H

V

V

L

K

E

R

A

V

Y

Y

L

L

binding adenosine-5'-diphosphate: Y12 (≠ F15), R15 (≠ L18), V17 (≠ A20), N37 (= N40), G38 (= G41), A39 (= A42), G40 (= G43), K41 (= K44), T42 (= T45), T43 (= T46)
binding magnesium ion: T42 (= T45), Q84 (= Q87)
binding novobiocin: L71 (≠ P74), H72 (≠ W75), Y81 (≠ R84), P83 (≠ F86), E85 (≠ N88), A86 (≠ L89), S87 (≠ R90), F89 (= F92), F89 (= F92), R90 (≠ P93), R91 (≠ N94), L92 (≠ M95), V101 (≠ F109), Q135 (≠ A149), R149 (= R163)

4p31A Crystal structure of a selenomethionine derivative of e. Coli lptb in complex with adp-magensium (see paper)
33% identity, 95% coverage: 6:248/255 of query aligns to 3:234/234 of 4p31A

query
sites
4p31A

L

L

S

T

I

A

Q

K

G

N

L

L

T

A

R

K

R

A

F
x
Y

G

K

G

G

L
x
R

L

R

A
x
V

V

V

S

E

D

D

V

V

S

S

A

L

T

T

I

V

A

N

K

S

G

G

E

E

L

I

V

V

G

G

L

L

I

L

G

G

P

P

N
|
N

G
|
G

A
|
A

G
|
G

K
|
K

T
|
T

T
|
T

L

T

F

F

N

Y

L

M

I

V

T

V

G

G

F

I

T

V

P

P

P

R

S

D

D

A

G

G

T

N

V

I

T

I

F

I

D

D

G

D

Q

D

D

D

V

I

T

S

G

L

R

L

K

P

P

L

W

H

Q

A

I

R

A

A

R

R

M

R

G

G

M

I

G

G

R

Y

T

L

F

P

Q
|
Q

N

E

L

A

R

S

V

I

F

F

P

R

N

R

M

L

T

S

V

V

F

Y

D

D

N

N

V

L

S

M

V

-

G

-

A

-

V

-

G

-

A

A

F

V

G

L

Q

Q

S

-

P

-

W

-

R

-

A

-

L

-

I

I

N

R

G

D

G

D

A

L

H

S

S

A

R

E

A

Q

V

R

S

E

E

D

R

R

S

A

W

N

E

E

A

L

L

M

E

E

R

E

V

F

G

H

L

I

T

E

A

H

Q

L

A

R

G

D

D

S

I

M

A

G

A

Q

N

S

L

L

S

S

Y

G

G

G

K

E

R

R

K

R

Y

R

L

V

E

E

I

I

A

A

R

R

A

A

L

L

A

A

T

A

A

N

P

P

R

K

L

F

L

I

I

L

L

L

D

D

E

E

P

P

A

F

A

A

G

G

L

V

N

D

D

P

T

I

E

S

T

V

A

I

E

D

L

I

A

K

D

R

F

I

I

I

R

E

R

H

L

L

H

R

A

D

G

S

G

G

V

L

T

G

V

V

L

L

L

I

V

T

E

D

H

H

D

N

M

V

G

R

L

E

V

T

M

L

G

A

S

V

C

C

S

E

R

R

V

A

I

Y

V

I

L

V

A

S

S

Q

G

G

R

H

K

L

I

I

A

A

D

H

G

G

T

T

P

P

E

T

A

E

V

I

Q

L

R

Q

D

D

P

E

A

H

V

V

L

K

E

R

A

V

Y

Y

L

L

binding adenosine-5'-diphosphate: Y12 (≠ F15), R15 (≠ L18), V17 (≠ A20), N37 (= N40), G38 (= G41), A39 (= A42), G40 (= G43), K41 (= K44), T42 (= T45), T43 (= T46)
binding magnesium ion: T42 (= T45), Q84 (= Q87)

1ji0A Crystal structure analysis of the abc transporter from thermotoga maritima
31% identity, 98% coverage: 1:250/255 of query aligns to 2:239/240 of 1ji0A

query
sites
1ji0A

M

V

S

S

N

D

T

I

L

V

L

L

S

E

I

V

Q

Q

G

S

L

L

T

H

R

V

R

Y

F
x
Y

G

G

G

A

L
x
I

L

H

A
|
A

V

I

S

K

D

G

V

I

S

D

A

L

T

K

I

V

A

P

K

R

G

G

E

Q

L

I

V

V

G

T

L

L

I

I

G

G

P

A

N
|
N

G
|
G

A
|
A

G
|
G

K
|
K

T
|
T

T
|
T

L

T

F

L

N

S

L

A

I

I

T

A

G

G

F

L

T

V

P

R

P

A

S

Q

D

K

G

G

T

K

V

I

T

I

F

F

D

N

G

G

Q

Q

D

D

V

I

T

T

G

N

R

K

K

P

P

A

W

H

Q

V

I

I

A

N

R

R

M

M

G

G

M

I

G

A

R

L

T

V

F

P

Q
x
E

N

G

L

R

R

R

V

I

F

F

P

P

N

E

M

L

T

T

V

V

F

Y

D

E

N

N

V

L

S

-

V

-

G

-

A

M

V

M

G

G

A

A

F

Y

G

N

Q

R

S

K

P

D

W

K

R

E

A

G

L

I

I

K

N

R

G

D

G

L

A

E

H

W

S

I

R

F

A

S

V

L

S

F

E

P

R

R

S

L

W

K

E

E

A

R

L

L

E

K

R

Q

V

L

G

G

L

G

T

T

A

-

Q

-

A

-

G

-

D

-

I

-

A

-

A

-

N

-

L

L

S

S

Y

G

G

G

K

E

R

Q

K

Q

Y

M

L

L

E

A

I

I

A

G

R

R

A

A

L

L

A

M

T

S

A

R

P

P

R

K

L

L

L

L

I

M

L

M

D
|
D

E
|
E

P

P

A

S

A

L

G

G

L

L

N

A

D

P

T

I

E

L

T

V

A

S

E

E

L

V

A

F

D

E

F

V

I

I

R

Q

R

K

L

I

H

N

A

Q

G

E

G

G

V

T

T

T

V

I

L

L

L

L

V

V

E

E

H

Q

D

N

M

A

G

L

L

G

V

A

M

L

G

K

S

V

C

A

S

H

R

Y

V

G

I

Y

V

V

L

L

A

E

S

T

G

G

R

Q

K

I

I

V

A

L

D

E

G

G

T

K

P

A

E

S

A

E

V

L

Q

L

R

D

D

N

P

E

A

M

V

V

L

R

E

K

A

A

Y

Y

L

L

G

G

V

V

binding adenosine-5'-triphosphate: Y16 (≠ F15), I19 (≠ L18), A21 (= A20), N41 (= N40), G42 (= G41), A43 (= A42), G44 (= G43), K45 (= K44), T46 (= T45), T47 (= T46), E88 (≠ Q87), D164 (= D175), E165 (= E176)

6b8bA E. Coli lptb in complex with adp and a novobiocin derivative (see paper)
32% identity, 95% coverage: 6:247/255 of query aligns to 3:233/233 of 6b8bA

query
sites
6b8bA

L

L

S

T

I

A

Q

K

G

N

L

L

T

A

R

K

R

A

F
x
Y

G

K

G

G

L
x
R

L

R

A
x
V

V

V

S

E

D

D

V

V

S

S

A

L

T

T

I

V

A

N

K

S

G

G

E

E

L

I

V

V

G

G

L

L

I

L

G

G

P

P

N
|
N

G
|
G

A
|
A

G
|
G

K
|
K

T
|
T

T
|
T

L

T

F

F

N

Y

L

M

I

V

T

V

G

G

F

I

T

V

P

P

P

R

S

D

D

A

G

G

T

N

V

I

T

I

F

I

D

D

G

D

Q

D

D

D

V

I

T

S

G

L

R

L

K

P

P

L

W

H

Q

A

I

R

A

A

R

R

M

R

G

G

M

I

G

G

R

Y

T

L

F

P

Q

Q

N

E

L

A

R

S

V

I

F
|
F

P
x
R

N
x
R

M

L

T

S

V

V

F

Y

D

D

N

N

V

L

S

M

V

-

G

-

A

-

V

-

G

-

A

A

F

V

G

L

Q

Q

S

-

P

-

W

-

R

-

A

-

L

-

I

I

N

R

G

D

G

D

A

L

H

S

S

A

R

E

A

Q

V

R

S

E

E

D

R

R

S

A

W

N

E

E

A

L

L

M

E

E

R

E

V

F

G

H

L

I

T

E

A

H

Q

L

A

R

G

D

D

S

I

M

A

G

A

Q

N

S

L

L

S

S

Y

G

G

G

K

E

R

R

K

R

Y

R

L

V

E

E

I

I

A

A

R

R

A

A

L

L

A

A

T

A

A

N

P

P

R

K

L

F

L

I

I

L

L

L

D

D

E

E

P

P

A

F

A

A

G

G

L

V

N

D

D

P

T

I

E

S

T

V

A

I

E

D

L

I

A

K

D

R

F

I

I

I

R

E

R

H

L

L

H

R

A

D

G

S

G

G

V

L

T

G

V

V

L

L

L

I

V

T

E

D

H

H

D

N

M

V

G

R

L

E

V

T

M

L

G

A

S

V

C

C

S

E

R

R

V

A

I

Y

V

I

L

V

A

S

S

Q

G

G

R

H

K

L

I

I

A

A

D

H

G

G

T

T

P

P

E

T

A

E

V

I

Q

L

R

Q

D

D

P

E

A

H

V

V

L

K

E

R

A

V

Y

Y

binding adenosine-5'-diphosphate: Y12 (≠ F15), R15 (≠ L18), V17 (≠ A20), N37 (= N40), G38 (= G41), A39 (= A42), G40 (= G43), K41 (= K44), T42 (= T45), T43 (= T46)
binding (3s,5s,7s)-N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-beta-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl}tricyclo[3.3.1.1~3,7~]decane-1-carboxamide: F89 (= F92), R90 (≠ P93), R91 (≠ N94)

4ymuJ Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
29% identity, 91% coverage: 5:237/255 of query aligns to 1:223/240 of 4ymuJ

query
sites
4ymuJ

L

M

L

I

S

F

I

V

Q

N

G

D

L

V

T

Y

R

K

R

N

F
|
F

G

G

G

S

L
|
L

L

E

A
x
V

V

L

S

K

D

G

V

V

S

T

A

L

T

K

I

V

A

N

K

K

G

G

E

E

L

V

V

V

G

V

L

I

I

I

G

G

P

P

N
x
S

G
|
G

A
x
S

G
|
G

K
|
K

T
x
S

T
|
T

L

L

F

L

N

R

L

C

I

I

T

N

G

L

F

L

T
x
E

P

E

P

P

S

T

D

K

G

G

T

E

V

V

T

F

F

I

D

D

G

G

Q

V

D

K

V

I

T

N

-

N

G

G

R

K

K

V

P

N

W

I

Q

N

I

K

A

V

R

R

M

Q

G

K

M

V

G

G

R

M

T

V

F

F

Q

Q

N

H

L

F

R

N

V

L

F

F

P

P

N

H

M

L

T

T

V

A

F

I

D

E

N

N

V

I

S

T

V

L

G

A

A

P

V

V

G

K

A

V

F

-

G

-

Q

-

S

-

P

-

W

-

R

-

A

-

L

-

I

-

N

-

G

K

G

K

A

M

H

N

S

K

R

K

A

E

V

A

S

E

E

E

R

L

S

A

W

V

E

D

A

L

L

L

E

A

R

K

V

V

G

G

L

L

T

L

A

D

Q

K

A

K

G

D

D

Q

I

Y

A

P

A

I

N

K

L

L

S

S

Y

G

G

G

K

Q

R

K

K

Q

Y

R

L

L

E

A

I

I

A

A

R

R

A

A

L

L

A

A

T

M

A

Q

P

P

R

E

L

V

L

M

I

L

L

F

D

D

E
|
E

P

P

A

T

A

S

G

A

L

L

N

D

D

P

T

E

E

M

T

V

A

K

E

E

L

V

A

L

D

N

F

V

I

M

R

K

R

Q

L

L

H

A

A

N

G

E

G

G

V

M

T

T

V

M

L

V

L

V

V

V

E

T

H
|
H

D

E

M

M

G

G

L

F

V

A

M

R

G

E

S

V

C

G

S

D

R

R

V

V

I

I

V

F

L

M

A

D

S

D

G

G

R

V

K

I

I

V

A

E

D

E

G

G

T

T

P

P

E

E

A

E

V

I

binding adenosine-5'-triphosphate: F11 (= F15), L14 (= L18), V16 (≠ A20), S36 (≠ N40), G37 (= G41), S38 (≠ A42), G39 (= G43), K40 (= K44), S41 (≠ T45), T42 (= T46), E51 (≠ T55), E162 (= E176), H194 (= H208)
binding magnesium ion: S41 (≠ T45), E162 (= E176)

P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 3 papers)
31% identity, 94% coverage: 5:244/255 of query aligns to 17:242/378 of P69874

query
sites
P69874

L

L

L

V

S

Q

I

L

Q

A

G

G

L

I

T

R

R

K

R
x
C

F
|
F

G

D

G

G

L

K

L

E

A

V

V

I

S

P

D

Q

V

L

S

D

A

L

T

T

I

I

A

N

K

N

G

G

E

E

L
x
F

V

L

G

T

L

L

I

L

G

G

P

P

N

S

G

G

A
x
C

G

G

K

K

T

T

T

T

L

V

F
x
L

N

R

L

L

I

I

T

A

G

G

F

L

T

E

P

T

P

V

S

D

D

S

G

G

T

R

V

I

T

M

F
x
L

D

D

G

N

Q

E

D

D

V

I

T

T

G

-

R

H

K

V

P

P

W

A

Q

E

I

-

A

-

R

N

M

R

G

Y

M

V

G

N

R

T

T

V

F

F

Q

Q

N

S

L

Y

R

A

V

L

F

F

P

P

N

H

M

M

T

T

V

V

F

F

D

E

N

N

V

V

S

A

V

F

G

G

A

L

V

-

G

-

A

R

F

M

G

Q

Q

K

S

T

P

P

W

-

R

-

A

-

L

-

I

-

N

-

G

-

G

-

A

-

H

-

S

A

R

A

A

E

V

I

S

T

E

P

R

R

S

V

W

M

E

E

A

A

L

L

E

R

R

M

V
|
V

G

Q

L

L

T

E

A

T

Q

F

A

A

G

Q

D

R

I

K

A

P

A

H

N

Q

L

L

S

S

Y

G

G

G

K

Q

R

Q

K

Q

Y

R

L

V

E

A

I

I

A

A

R

R

A

A

L

V

A

V

T

N

A

K

P

P

R

R

L

L

L

L

I

L

L

L

D
|
D

E

E

P

S

A

L

A

S

G

A

L

L

N

D

D

Y

T

K

E

L

T

R

A

K

E

Q

L

M

A

Q

D

N

F

E

I

L

R

K

R

A

L

L

H

Q

A

R

G

K

-

L

G

G

V

I

T

T

V

F

L

V

L

F

V

V

E

T

H

H

D

D

M

Q

G

E

L

E

V

A

M

L

G

T

S

M

C

S

S

D

R

R

V

I

I

V

V

V

L

M

A

R

S

D

G

G

R

R

K

I

I

E

A

Q

D

D

G

G

T

T

P

P

E

R

A

E

V

I

Q

Y

R

E

D

E

P

P

A

K

V

N

L

L

C26 (≠ R14) mutation to A: Lower ATPase activity and transport efficiency.
F27 (= F15) mutation to L: Lower ATPase activity and transport efficiency.
F45 (≠ L33) mutation to L: Lower ATPase activity and transport efficiency.
C54 (≠ A42) mutation to T: Loss of ATPase activity and transport.
L60 (≠ F48) mutation to F: Lower ATPase activity and transport efficiency.
L76 (≠ F64) mutation to P: Lower ATPase activity and transport efficiency.
V135 (= V138) mutation to M: Loss of ATPase activity and transport.
D172 (= D175) mutation to N: Loss of ATPase activity and transport.

Sites not aligning to the query:

276 C→A: Lower ATPase activity and transport efficiency.
297 mutation E->K,D: Lower ATPase activity and transport efficiency.; E→Q: Loss of ATPase activity and transport.

P04983 Ribose import ATP-binding protein RbsA; EC 7.5.2.7 from Escherichia coli (strain K12) (see paper)
28% identity, 96% coverage: 5:249/255 of query aligns to 4:239/501 of P04983

query
sites
P04983

L

L

L

L

S

Q

I

L

Q

K

G

G

L

I

T

D

R

K

R

A

F

F

G

P

G

G

L

V

L

K

A

A

V

L

S

S

D

G

V

A

S

A

A

L

T

N

I

V

A

Y

K

P

G

G

E

R

L

V

V

M

G

A

L

L

I

V

G

G

P

E

N

N

G

G

A

A

G

G

K
|
K

T

S

T

T

L

M

F

M

N

K

L

V

I

L

T

T

G

G

F

I

T

Y

P

T

P

R

S

D

D

A

G

G

T

T

V

L

T

L

F

W

D

L

G

G

Q

K

D

E

V

T

T

T

G

F

R

T

K

G

P

P

W

K

Q

S

I

S

A

Q

R

E

M

A

G

G

M

I

G

G

R

I

T

I

F

H

Q

Q

N

E

L

L

R

N

V

L

F

I

P

P

N

Q

M

L

T

T

V

I

F

A

D

E

N

N

V

I

S

F

V

L

G

G

A

R

-

E

-

F

V

V

G

N

A

R

F

F

G

G

Q

K

S

I

P

D

W

W

R

K

A

T

L

M

I

Y

N

-

G

-

G

-

A

-

H

-

S

-

R

-

A

-

V

-

S

-

E

A

R

E

S

A

W

D

E

K

A

L

L

L

E

A

R

K

V

L

G

N

L

L

T

R

A

F

Q

K

A

S

G

D

D

K

I

L

A

V

A

G

N

D

L

L

S

S

Y

I

G

G

K

D

R

Q

K

Q

Y

M

L

V

E

E

I

I

A

A

R

K

A

V

L

L

A

S

T

F

A

E

P

S

R

K

L

V

L

I

I

I

L

M

D

D

E

E

P

P

A

T

A

D

G

A

L

L

N

T

D

D

T

T

E

E

T

T

A

E

E

S

L

L

A

F

D

R

F

V

I

I

R

R

R

E

L

L

H

K

A

S

G

Q

G

G

V

R

T

G

V

I

L

V

L

Y

V

I

E

S

H

H

D

R

M

M

G

K

L

E

V

I

M

F

G

E

S

I

C

C

S

D

R

D

V

V

I

T

V

V

L

F

A

R

S

D

G

G

R

Q

K

F

I

I

A

A

D

E

G

R

T

E

P

V

E

A

A

S

V

L

Q

T

R

E

D

D

P

-

A

S

V

L

L

I

E

E

A

M

Y

M

L

V

G

G

K43 (= K44) mutation to R: Loss of transport.

3c4jA Abc protein artp in complex with atp-gamma-s
28% identity, 91% coverage: 5:235/255 of query aligns to 3:223/242 of 3c4jA

query
sites
3c4jA

L

M

L

I

S

D

I

V

Q

H

G

Q

L

L

T

K

R

K

R

S

F
|
F

G

G

G

S

L

L

L

E

A
x
V

V

L

S

K

D

G

V

I

S

N

A

V

T

H

I

I

A

R

K

E

G

G

E

E

L

V

V

V

G

V

L

V

I

I

G

G

P
|
P

N
x
S

G
|
G

A
x
S

G
|
G

K
|
K

T
x
S

T
|
T

L

F

F

L

N

R

L

C

I

L

T

N

G

L

F

L

T

E

P

D

P

F

S

D

D

E

G

G

T

E

V

I

T

I

F

I

D

D

G

G

Q

I

D

N

V

L

T

K

G

A

R

K

K

D

P

T

-

N

W

L

Q

N

I

K

A

V

R

R

M

E

G

E

M

V

G

G

R

M

T

V

F

F

Q

Q

N

R

L

F

R

N

V

L

F

F

P

P

N

H

M

M

T

T

V

V

F

L

D

N

N

N

V

I

S

T

V

L

G

A

A

P

V

M

G

K

A

V

F

-

G

-

Q

-

S

R

P

K

W

W

R

-

A

-

L

-

I

-

N

-

G

-

G

-

A

-

H

-

S

P

R

R

A

E

V

K

S

A

E

E

-

A

R

K

S

A

W

M

E

E

A

L

L

L

E

D

R

K

V

V

G

G

L

L

T

K

A

D

Q

K

A

A

G
x
H

D

A

I
x
Y

A

P

A

D

N

S

L

L

S

S

Y

G

G

G

K

Q

R

A

K

Q

Y

R

L

V

E

A

I

I

A

A

R

R

A

A

L

L

A

A

T

M

A

E

P

P

R

K

L

I

L

M

I

L

L

F

D

D

E
|
E

P

P

A

T

A

S

G

A

L

L

N

D

D

P

T

E

E

M

T

V

A

G

E

E

L

V

A

L

D

S

F

V

I

M

R

K

R

Q

L

L

H

A

A

N

G

E

G

G

V

M

T

T

V

M

L

V

L

V

V

V

E

T

H

H

D

E

M

M

G

G

L

F

V

A

M

R

G

E

S

V

C

G

S

D

R

R

V

V

I

L

V

F

L

M

A

D

S

G

G

G

R

Y

K

I

I

I

A

E

D

E

G

G

T

K

P

P

E

E

binding phosphothiophosphoric acid-adenylate ester: F13 (= F15), V18 (≠ A20), P37 (= P39), S38 (≠ N40), G39 (= G41), S40 (≠ A42), G41 (= G43), K42 (= K44), S43 (≠ T45), T44 (= T46), H133 (≠ G145), Y135 (≠ I147), E164 (= E176)

3c41J Abc protein artp in complex with amp-pnp/mg2+
28% identity, 91% coverage: 5:235/255 of query aligns to 3:223/242 of 3c41J

query
sites
3c41J

L

M

L

I

S

D

I

V

Q

H

G

Q

L

L

T

K

R

K

R

S

F
|
F

G

G

G

S

L

L

L

E

A
x
V

V

L

S

K

D

G

V

I

S

N

A

V

T

H

I

I

A

R

K

E

G

G

E

E

L

V

V

V

G

V

L

V

I

I

G

G

P
|
P

N
x
S

G
|
G

A
x
S

G
|
G

K
|
K

T
x
S

T
|
T

L

F

F

L

N
x
R

L

C

I

L

T

N

G

L

F

L

T

E

P

D

P

F

S

D

D

E

G

G

T

E

V

I

T

I

F

I

D

D

G

G

Q

I

D

N

V

L

T

K

G

A

R

K

K

D

P

T

-

N

W

L

Q

N

I

K

A

V

R

R

M

E

G

E

M

V

G

G

R

M

T

V

F

F

Q

Q

N

R

L

F

R

N

V

L

F

F

P

P

N

H

M

M

T

T

V

V

F

L

D

N

N

N

V

I

S

T

V

L

G

A

A

P

V

M

G

K

A

V

F

-

G

-

Q

-

S

R

P

K

W

W

R

-

A

-

L

-

I

-

N

-

G

-

G

-

A

-

H

-

S

P

R

R

A

E

V

K

S

A

E

E

-

A

R

K

S

A

W

M

E

E

A

L

L

L

E

D

R

K

V

V

G

G

L

L

T

K

A

D

Q

K

A

A

G
x
H

D

A

I
x
Y

A

P

A

D

N

S

L

L

S

S

Y

G

G

G

K

Q

R

A

K

Q

Y

R

L

V

E

A

I

I

A

A

R

R

A

A

L

L

A

A

T

M

A

E

P

P

R

K

L

I

L

M

I

L

L

F

D
|
D

E

E

P

P

A

T

A

S

G

A

L

L

N

D

D

P

T

E

E

M

T

V

A

G

E

E

L

V

A

L

D

S

F

V

I

M

R

K

R

Q

L

L

H

A

A

N

G

E

G

G

V

M

T

T

V

M

L

V

L

V

V

V

E

T

H

H

D

E

M

M

G

G

L

F

V

A

M

R

G

E

S

V

C

G

S

D

R

R

V

V

I

L

V

F

L

M

A

D

S

G

G

G

R

Y

K

I

I

I

A

E

D

E

G

G

T

K

P

P

E

E

binding phosphoaminophosphonic acid-adenylate ester: F13 (= F15), V18 (≠ A20), P37 (= P39), S38 (≠ N40), G39 (= G41), S40 (≠ A42), G41 (= G43), K42 (= K44), S43 (≠ T45), T44 (= T46), R47 (≠ N49), H133 (≠ G145), Y135 (≠ I147)
binding magnesium ion: S43 (≠ T45), D163 (= D175)

2olkA Abc protein artp in complex with adp-beta-s
28% identity, 91% coverage: 5:235/255 of query aligns to 3:223/242 of 2olkA

query
sites
2olkA

L

M

L

I

S

D

I

V

Q

H

G

Q

L

L

T

K

R

K

R

S

F
|
F

G

G

G

S

L
|
L

L

E

A
x
V

V

L

S

K

D

G

V

I

S

N

A

V

T

H

I

I

A

R

K

E

G

G

E

E

L

V

V

V

G

V

L

V

I

I

G

G

P

P

N
x
S

G
|
G

A
x
S

G
|
G

K
|
K

T
x
S

T
|
T

L

F

F

L

N

R

L

C

I

L

T

N

G

L

F

L

T

E

P

D

P

F

S

D

D

E

G

G

T

E

V

I

T

I

F

I

D

D

G

G

Q

I

D

N

V

L

T

K

G

A

R

K

K

D

P

T

-

N

W

L

Q

N

I

K

A

V

R

R

M

E

G

E

M

V

G

G

R

M

T

V

F

F

Q

Q

N

R

L

F

R

N

V

L

F

F

P

P

N

H

M

M

T

T

V

V

F

L

D

N

N

N

V

I

S

T

V

L

G

A

A

P

V

M

G

K

A

V

F

-

G

-

Q

-

S

R

P

K

W

W

R

-

A

-

L

-

I

-

N

-

G

-

G

-

A

-

H

-

S

P

R

R

A

E

V

K

S

A

E

E

-

A

R

K

S

A

W

M

E

E

A

L

L

L

E

D

R

K

V

V

G

G

L

L

T

K

A

D

Q

K

A

A

G

H

D

A

I

Y

A

P

A

D

N

S

L

L

S

S

Y

G

G

G

K

Q

R

A

K

Q

Y

R

L

V

E

A

I

I

A

A

R

R

A

A

L

L

A

A

T

M

A

E

P

P

R

K

L

I

L

M

I

L

L

F

D

D

E

E

P

P

A

T

A

S

G

A

L

L

N

D

D

P

T

E

E

M

T

V

A

G

E

E

L

V

A

L

D

S

F

V

I

M

R

K

R

Q

L

L

H

A

A

N

G

E

G

G

V

M

T

T

V

M

L

V

L

V

V

V

E

T

H

H

D

E

M

M

G

G

L

F

V

A

M

R

G

E

S

V

C

G

S

D

R

R

V

V

I

L

V

F

L

M

A

D

S

G

G

G

R

Y

K

I

I

I

A

E

D

E

G

G

T

K

P

P

E

E

binding 5'-o-[(r)-hydroxy(thiophosphonooxy)phosphoryl]adenosine: F13 (= F15), L16 (= L18), V18 (≠ A20), S38 (≠ N40), G39 (= G41), S40 (≠ A42), G41 (= G43), K42 (= K44), S43 (≠ T45), T44 (= T46)

2oljA Abc protein artp in complex with adp/mg2+
28% identity, 91% coverage: 5:235/255 of query aligns to 3:223/242 of 2oljA

query
sites
2oljA

L

M

L

I

S

D

I

V

Q

H

G

Q

L

L

T

K

R

K

R

S

F
|
F

G

G

G

S

L

L

L

E

A
x
V

V

L

S

K

D

G

V

I

S

N

A

V

T

H

I

I

A

R

K

E

G

G

E

E

L

V

V

V

G

V

L

V

I

I

G

G

P

P

N
x
S

G
|
G

A
x
S

G
|
G

K
|
K

T
x
S

T
|
T

L

F

F

L

N

R

L

C

I

L

T

N

G

L

F

L

T

E

P

D

P

F

S

D

D

E

G

G

T

E

V

I

T

I

F

I

D

D

G

G

Q

I

D

N

V

L

T

K

G

A

R

K

K

D

P

T

-

N

W

L

Q

N

I

K

A

V

R

R

M

E

G

E

M

V

G

G

R

M

T

V

F

F

Q

Q

N

R

L

F

R

N

V

L

F

F

P

P

N

H

M

M

T

T

V

V

F

L

D

N

N

N

V

I

S

T

V

L

G

A

A

P

V

M

G

K

A

V

F

-

G

-

Q

-

S

R

P

K

W

W

R

-

A

-

L

-

I

-

N

-

G

-

G

-

A

-

H

-

S

P

R

R

A

E

V

K

S

A

E

E

-

A

R

K

S

A

W

M

E

E

A

L

L

L

E

D

R

K

V

V

G

G

L

L

T

K

A

D

Q

K

A

A

G
x
H

D

A

I
x
Y

A

P

A

D

N

S

L

L

S

S

Y

G

G

G

K

Q

R

A

K

Q

Y

R

L

V

E

A

I

I

A

A

R

R

A

A

L

L

A

A

T

M

A

E

P

P

R

K

L

I

L

M

I

L

L

F

D

D

E

E

P

P

A

T

A

S

G

A

L

L

N

D

D

P

T

E

E

M

T

V

A

G

E

E

L

V

A

L

D

S

F

V

I

M

R

K

R

Q

L

L

H

A

A

N

G

E

G

G

V

M

T

T

V

M

L

V

L

V

V

V

E

T

H

H

D

E

M

M

G

G

L

F

V

A

M

R

G

E

S

V

C

G

S

D

R

R

V

V

I

L

V

F

L

M

A

D

S

G

G

G

R

Y

K

I

I

I

A

E

D

E

G

G

T

K

P

P

E

E

binding adenosine-5'-diphosphate: F13 (= F15), V18 (≠ A20), S38 (≠ N40), G39 (= G41), S40 (≠ A42), G41 (= G43), K42 (= K44), S43 (≠ T45), T44 (= T46), H133 (≠ G145), Y135 (≠ I147)

A5U7B7 Cell division ATP-binding protein FtsE from Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) (see 2 papers)
34% identity, 83% coverage: 20:231/255 of query aligns to 18:219/229 of A5U7B7

query
sites
A5U7B7

A

A

V

L

S

D

D

D

V

I

S