Comparing Ac3H11_1505 FitnessBrowser__acidovorax_3H11:Ac3H11_1505 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 7 hits to proteins with known functional sites (download)
4f4fA X-ray crystal structure of plp bound threonine synthase from brucella melitensis
43% identity, 99% coverage: 1:474/481 of query aligns to 2:461/464 of 4f4fA
1kl7A Crystal structure of threonine synthase from yeast (see paper)
40% identity, 99% coverage: 3:476/481 of query aligns to 7:507/509 of 1kl7A
Q42598 Threonine synthase; TS; EC 4.2.3.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
39% identity, 94% coverage: 1:452/481 of query aligns to 5:485/514 of Q42598
8g1yA Crystal structure of the threonine synthase from streptococcus pneumoniae in complex with pyridoxal 5-phosphate.
37% identity, 91% coverage: 1:437/481 of query aligns to 5:440/496 of 8g1yA
1vb3A Crystal structure of threonine synthase from escherichia coli
28% identity, 99% coverage: 1:474/481 of query aligns to 1:427/428 of 1vb3A
6nmxA Threonine synthase from bacillus subtilis atcc 6633 with plp and appa (see paper)
30% identity, 36% coverage: 95:268/481 of query aligns to 31:193/350 of 6nmxA
Sites not aligning to the query:
6cgqB Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala (see paper)
30% identity, 36% coverage: 95:268/481 of query aligns to 29:191/345 of 6cgqB
Sites not aligning to the query:
>Ac3H11_1505 FitnessBrowser__acidovorax_3H11:Ac3H11_1505
MKYLSTRGHADRKQFCDILLEGLAPDGGLYLPETYPKITAAALTKLRKAYHEQGYAELAF
QILSLYIDDIPAADLKAICAKTYTAEVFGTGEIVPLRHLEDGLWLEALSNGPTLAFKDMA
MQLLGNLFEYELGRRGEQLNILGATSGDTGSAAEYAMRGKEGVRVFMTSPHGRMSAFQQA
QMFSLQDENIHNIAIEGVFDDCQDIVKAVSNDHAFKAKYKIGTVNSINWARLLAQVVYYF
AGYIQATETNNQKVSFTVPSGNFGNICAGHVARMMGLPIAKLVVATNENDVLDEFFRTGV
YRVRGSADTHETSSPSMDISKASNFERFIFDLLGRNGQRTKALFSAALQTYGRFDLSADP
LFADAAKKYGFESGKSTHADRLATIKDTFERHGVTIDTHTADGVKVAREHHSDAKVPMIV
LETALPIKFAETIIEALGHAPERPAKFAGIEDLPKRVHVMPADVEQVKAYIERHCAPAAQ
G
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory