Comparing Ac3H11_167 FitnessBrowser__acidovorax_3H11:Ac3H11_167 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 10 hits to proteins with known functional sites (download)
4lhdA Crystal structure of synechocystis sp. Pcc 6803 glycine decarboxylase (p-protein), holo form with pyridoxal-5'-phosphate and glycine, closed flexible loop (see paper)
58% identity, 98% coverage: 14:963/970 of query aligns to 13:949/952 of 4lhdA
Sites not aligning to the query:
Q94B78 Glycine dehydrogenase (decarboxylating) 1, mitochondrial; Glycine cleavage system P protein 1; Glycine decarboxylase 1; Glycine decarboxylase P-protein 1; AtGLDP1; Glycine dehydrogenase (aminomethyl-transferring) 1; EC 1.4.4.2 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
54% identity, 99% coverage: 8:965/970 of query aligns to 67:1026/1037 of Q94B78
6i33A Crystal structure of human glycine decarboxylase (p-protein)
52% identity, 98% coverage: 19:966/970 of query aligns to 14:950/950 of 6i33A
6i34B Crystal structure of neanderthal glycine decarboxylase (p-protein)
52% identity, 98% coverage: 19:965/970 of query aligns to 12:954/954 of 6i34B
6i35A Crystal structure of human glycine decarboxylase (p-protein) bound with pyridoxyl-glycine-5'-monophosphate
52% identity, 98% coverage: 19:966/970 of query aligns to 14:953/953 of 6i35A
P15505 Glycine dehydrogenase (decarboxylating), mitochondrial; Glycine cleavage system P protein; Glycine decarboxylase; Glycine dehydrogenase (aminomethyl-transferring); EC 1.4.4.2 from Gallus gallus (Chicken) (see paper)
50% identity, 98% coverage: 19:969/970 of query aligns to 52:992/1004 of P15505
6i33B Crystal structure of human glycine decarboxylase (p-protein)
50% identity, 98% coverage: 19:965/970 of query aligns to 12:925/925 of 6i33B
1wyuB Crystal structure of glycine decarboxylase (p-protein) of the glycine cleavage system, in holo form (see paper)
40% identity, 44% coverage: 491:913/970 of query aligns to 45:450/473 of 1wyuB
1wyvA Crystal structure of glycine decarboxylase (p-protein) of the glycine cleavage system, in inhibitor-bound form (see paper)
41% identity, 35% coverage: 35:371/970 of query aligns to 14:348/437 of 1wyvA
1wyuA Crystal structure of glycine decarboxylase (p-protein) of the glycine cleavage system, in holo form (see paper)
41% identity, 35% coverage: 35:371/970 of query aligns to 14:348/437 of 1wyuA
>Ac3H11_167 FitnessBrowser__acidovorax_3H11:Ac3H11_167
MTAALPTSLPLSALENAAEFLPRHIGIDAADEAHMLSVIGEASRRTLIDSIVPRSIARSR
AMDLPAATTEAAALAELKAIAGKNKVLKSFIGQGYYGTHTPGVILRNILENPAWYTAYTP
YQAEISQGRMEALVNFQTMVCDLTGMPIANASMLDEATAAAEAMTLAKRSVKSKSNVFVV
AGDAHPQTIEVIQTRAKPLGLDVRLANSAEEWDSLLAGDYFAVLAQYPATSGRIDDLRAD
VEKAHAKQAAFIVAADLLALTLITPPGEQGADIVVGTTQRFGMPMGAGGPHAAFMACRDE
FKRSLPGRLVGVSVDVHGKPAYRLALQTREQHIRREKATSNICTAQVLPAVVASMYAVYH
GPEGLSRIAQRVASYTAILARGLVQLGAPVREQATFDTLVLKTDGATKSIATKAIQSGAN
LRIYFESYLCISLDETTTRADIELLWKVFAKDGQALPTFDAFENGVEPLIPAALRRTSRY
LTHPVFNTHHSETGMLRYIRQLSDKDLALDRSMIPLGSCTMKLNATSEMIPITWPEFANM
HPFAPADQQQGYKALDEQLRAWLCEATGYAGISLQPNAGSQGEYAGLLAIKGYHESRGEG
HRNICLIPSSAHGTNPASAQMVGMQVVVTACDANGNVDLADLQAKCEQHSGNIACVMITY
PSTHGVFETSVKELCALVHSHGGRVYVDGANMNALVGVAAPGEFGGDVSHLNLHKTFCIP
HGGGGPGVGPVCVVEDLVPFLPGLPGQGDQPKSPATGKVGPVSAAPLGNAAVLPISWMYI
RMMGADGLQAATETAILSANYISARLKDHYPTLYASENGHVAHECILDLRGLKDTSGVMA
EDVAKRLIDYGFHAPTLSFPVPNTLMVEPTESETLFEIDRFIDAMIAIREEIRQIEAGKL
PQDNNPLKNAPHTAENLLSGEWTRPYTREAAAYPVAALRQAKYWSPVGRVDNVWGDRNLS
CSCIPVSDYA
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory