Comparing Ac3H11_2391 FitnessBrowser__acidovorax_3H11:Ac3H11_2391 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
2wltA The crystal structure of helicobacter pylori l-asparaginase at 1.4 a resolution (see paper)
37% identity, 98% coverage: 6:317/317 of query aligns to 4:314/326 of 2wltA
5k45A Wolinella succinogenes l-asparaginase p121 + l-glutamic acid (see paper)
38% identity, 98% coverage: 5:315/317 of query aligns to 3:314/328 of 5k45A
5k3oA Wolinella succinogenes l-asparaginase p121 and l-aspartic acid (see paper)
38% identity, 98% coverage: 5:315/317 of query aligns to 3:314/328 of 5k3oA
2gvnA L-asparaginase from erwinia carotovora in complex with aspartic acid (see paper)
36% identity, 98% coverage: 5:315/317 of query aligns to 4:311/325 of 2gvnA
P06608 L-asparaginase; L-ASNase; L-asparagine amidohydrolase; EC 3.5.1.1 from Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi) (see 2 papers)
37% identity, 98% coverage: 5:315/317 of query aligns to 27:334/348 of P06608
1jsrA Crystal structure of erwinia chrysanthemi l-asparaginase complexed with 6-hydroxy-l-norleucine (see paper)
37% identity, 97% coverage: 5:313/317 of query aligns to 3:308/324 of 1jsrA
1jslA Crystal structure of erwinia chrysanthemi l-asparaginase complexed with 6-hydroxy-d-norleucine (see paper)
37% identity, 97% coverage: 5:313/317 of query aligns to 3:308/324 of 1jslA
1hg0A X-ray structure of the complex between erwinia chrysanthemi l- asparaginase and succinic acid (see paper)
37% identity, 98% coverage: 5:315/317 of query aligns to 6:313/327 of 1hg0A
7u6mC Albumin binding domain fused to a mutant of the erwinia asparaginase (see paper)
36% identity, 97% coverage: 5:313/317 of query aligns to 21:326/342 of 7u6mC
P00805 L-asparaginase 2; L-asparaginase II; L-ASNase II; L-asparagine amidohydrolase II; Colaspase; EC 3.5.1.1 from Escherichia coli (strain K12) (see 5 papers)
38% identity, 91% coverage: 27:315/317 of query aligns to 46:334/348 of P00805
Sites not aligning to the query:
1ho3A Crystal structure analysis of e. Coli l-asparaginase ii (y25f mutant) (see paper)
38% identity, 92% coverage: 27:317/317 of query aligns to 24:314/326 of 1ho3A
Sites not aligning to the query:
2hlnA L-asparaginase from erwinia carotovora in complex with glutamic acid (see paper)
35% identity, 98% coverage: 5:315/317 of query aligns to 4:294/308 of 2hlnA
1jazA Crystal structure of monoclinic form of d90e mutant of escherichia coli asparaginase ii (see paper)
36% identity, 99% coverage: 5:317/317 of query aligns to 3:295/307 of 1jazA
7r5qA Escherichia coli type ii asparaginase n24s mutant in complex with glu (see paper)
36% identity, 99% coverage: 5:317/317 of query aligns to 3:294/306 of 7r5qA
P10182 Glutaminase-asparaginase; L-ASNase/L-GLNase; L-asparagine/L-glutamine amidohydrolase; PGA; EC 3.5.1.38 from Pseudomonas sp. (strain ATCC 29598 / 7A) (see paper)
34% identity, 91% coverage: 28:317/317 of query aligns to 34:325/337 of P10182
Sites not aligning to the query:
1hg1A X-ray structure of the complex between erwinia chrysanthemi l-asparaginase and d-aspartate (see paper)
35% identity, 97% coverage: 5:313/317 of query aligns to 3:290/306 of 1hg1A
6pa3A E. Coli l-asparaginase ii double mutant (t89v,k162t) in complex with l-asn at ph 7.0 (see paper)
38% identity, 91% coverage: 27:315/317 of query aligns to 32:320/334 of 6pa3A
Sites not aligning to the query:
6wywA Crystal structure of pseudomonas 7a glutaminase-asparaginase in complex with l-asp at ph 4.5
34% identity, 96% coverage: 5:307/317 of query aligns to 3:295/317 of 6wywA
1hfwA X-ray structure of the complex between erwinia chrysanthemi l-asparaginase and l-glutamate (see paper)
35% identity, 97% coverage: 5:313/317 of query aligns to 4:291/307 of 1hfwA
4pgaA Glutaminase-asparaginase from pseudomonas 7a (see paper)
35% identity, 88% coverage: 28:307/317 of query aligns to 27:308/330 of 4pgaA
Sites not aligning to the query:
>Ac3H11_2391 FitnessBrowser__acidovorax_3H11:Ac3H11_2391
VSGQKIVVLGTGGTIAGTSAQAGDNIGYTAAQVGVEQLLAAVPGLQALAGGTLVVEQVAQ
VDSKDMDDGVWRALAQRCAHHLADPDVRGLVITHGTDTLEETAWFLHEVLDTTKPVVLTC
AMRPATALTPDGPQNLLDAVAVVLAPGATGVVAVAAGELHAARNVQKVHPYRVHAFNSGD
AGPLGWVEEGRVRFVQNWPLPPVGRAFTAIKTGIESAEWPWVEVVLSHAGARAQTVDALV
HAGVRGLVVACTGNGTIHHALDAALLRAQQAGVRVVRATRCAEGQVLPKPGDVLPDSRGL
SPVKARVALLLDLLQAH
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory