Comparing Ac3H11_256 FitnessBrowser__acidovorax_3H11:Ac3H11_256 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
1o4sB Crystal structure of aspartate aminotransferase (tm1255) from thermotoga maritima at 1.90 a resolution (see paper)
32% identity, 93% coverage: 25:388/390 of query aligns to 38:382/384 of 1o4sB
1j32A Aspartate aminotransferase from phormidium lapideum
31% identity, 98% coverage: 10:390/390 of query aligns to 19:386/388 of 1j32A
P14909 Aspartate aminotransferase; AspAT; Transaminase A; EC 2.6.1.1 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
29% identity, 99% coverage: 2:387/390 of query aligns to 23:394/402 of P14909
Sites not aligning to the query:
1gdeA Crystal structure of pyrococcus protein a-1 e-form (see paper)
30% identity, 97% coverage: 11:389/390 of query aligns to 12:383/388 of 1gdeA
1gd9A Crystall structure of pyrococcus protein-a1 (see paper)
30% identity, 97% coverage: 11:389/390 of query aligns to 12:383/388 of 1gd9A
5wmiA Arabidopsis thaliana prephenate aminotransferase mutant- t84v (see paper)
31% identity, 99% coverage: 5:389/390 of query aligns to 7:397/402 of 5wmiA
5wmhA Arabidopsis thaliana prephenate aminotransferase (see paper)
31% identity, 93% coverage: 26:389/390 of query aligns to 31:397/399 of 5wmhA
Q58097 (5-formylfuran-3-yl)methyl phosphate transaminase; 4-HFC-P:alanine aminotransferase; EC 2.6.1.108 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
28% identity, 93% coverage: 26:388/390 of query aligns to 31:368/370 of Q58097
5wmlA Arabidopsis thaliana prephenate aminotransferase mutant- k306a (see paper)
30% identity, 93% coverage: 26:389/390 of query aligns to 32:398/404 of 5wmlA
Sites not aligning to the query:
8wkjA The crystal structure of aspartate aminotransferases lpg0070 from legionella pneumophila (see paper)
28% identity, 93% coverage: 25:387/390 of query aligns to 32:389/391 of 8wkjA
5yhvB Crystal structure of an aminotransferase from mycobacterium tuberculosis
32% identity, 93% coverage: 25:388/390 of query aligns to 31:384/387 of 5yhvB
5yhvA Crystal structure of an aminotransferase from mycobacterium tuberculosis
32% identity, 93% coverage: 25:388/390 of query aligns to 38:391/394 of 5yhvA
P96847 Valine--pyruvate aminotransferase; Alanine--valine transaminase; EC 2.6.1.66 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
32% identity, 93% coverage: 25:388/390 of query aligns to 32:385/388 of P96847
6f35A Crystal structure of the aspartate aminotranferase from rhizobium meliloti (see paper)
29% identity, 91% coverage: 32:384/390 of query aligns to 39:392/400 of 6f35A
1b5oA Thermus thermophilus aspartate aminotransferase single mutant 1 (see paper)
30% identity, 89% coverage: 25:373/390 of query aligns to 32:368/382 of 1b5oA
1bkgA Aspartate aminotransferase from thermus thermophilus with maleate (see paper)
30% identity, 89% coverage: 25:373/390 of query aligns to 32:368/382 of 1bkgA
1bjwA Aspartate aminotransferase from thermus thermophilus (see paper)
30% identity, 89% coverage: 25:373/390 of query aligns to 32:368/382 of 1bjwA
Q56232 Aspartate/prephenate aminotransferase; AspAT / PAT; Transaminase A; EC 2.6.1.1; EC 2.6.1.78 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 3 papers)
30% identity, 89% coverage: 25:373/390 of query aligns to 32:368/385 of Q56232
Sites not aligning to the query:
1gc4A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with aspartate (see paper)
30% identity, 89% coverage: 25:373/390 of query aligns to 32:368/382 of 1gc4A
1gc3A Thermus thermophilus aspartate aminotransferase tetra mutant 2 complexed with tryptophan (see paper)
30% identity, 89% coverage: 25:373/390 of query aligns to 32:368/382 of 1gc3A
Sites not aligning to the query:
>Ac3H11_256 FitnessBrowser__acidovorax_3H11:Ac3H11_256
MREVVQSLEESRIREVANEGLGRSDVLQFWFGESDEVTPDFIRDAAIASLQKGETFYAHN
LGLPELRHAIAGYMHGLHPQQHTDAWFDRIAVTSGGVNGLMVAVQALVDAGDEVVLVTPV
WPNLVAQPRILGAQVRTVPLVADADGAWQLDMDALLAAITPGTRLLVVNAPNNPTGWTLT
REEQATILAHCRRTGTWIVADEVYERLYYAGDTANGAAPSFLDVAEPEDRLVVTHSFSKS
FLMTGWRLGWLVLPPSMTPAVGKLIEFNTSCAPVFVQRGATVALQRTDEVTPALVNHLRN
CRDTLVPLLADVPGVSVATPRGGMYAFFHIDGHDECLPLAKRLVREAGLGLAPGSAFGGE
ASGWLRWCFASRDVGRLGEGVGRLRGWLKG
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory