Comparing Ac3H11_3736 FitnessBrowser__acidovorax_3H11:Ac3H11_3736 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 15 hits to proteins with known functional sites (download)
P45131 Homoserine O-acetyltransferase; HAT; Homoserine O-trans-acetylase; Homoserine transacetylase; HTA; EC 2.3.1.31 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 2 papers)
32% identity, 73% coverage: 46:303/355 of query aligns to 19:309/358 of P45131
Sites not aligning to the query:
2vavB Crystal structure of deacetylcephalosporin c acetyltransferase (dac- soak) (see paper)
31% identity, 49% coverage: 41:213/355 of query aligns to 19:197/350 of 2vavB
Sites not aligning to the query:
2vatA Crystal structure of deacetylcephalosporin c acetyltransferase in complex with coenzyme a (see paper)
31% identity, 49% coverage: 41:213/355 of query aligns to 18:196/347 of 2vatA
Sites not aligning to the query:
Q6FEQ3 Homoserine O-succinyltransferase; HST; Homoserine transsuccinylase; HTS; EC 2.3.1.46 from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
28% identity, 52% coverage: 28:213/355 of query aligns to 3:211/387 of Q6FEQ3
Sites not aligning to the query:
D2Z028 L-serine/homoserine O-acetyltransferase; Homoserine O-trans-acetylase; EC 2.3.1.30; EC 2.3.1.31 from Streptomyces lavendulae (see paper)
28% identity, 49% coverage: 41:213/355 of query aligns to 18:204/374 of D2Z028
8f2lA Crystal structure of mycobacterium tuberculosis homoserine transacetylase in complex with l-homoserine (see paper)
28% identity, 51% coverage: 38:219/355 of query aligns to 15:211/367 of 8f2lA
Sites not aligning to the query:
6puxA Homoserine transacetylase metx from mycobacterium tuberculosis (see paper)
28% identity, 51% coverage: 38:219/355 of query aligns to 16:212/366 of 6puxA
Sites not aligning to the query:
7rytB Crystal structure of mycobacterium tuberculosis acetylated homoserine transacetylase with coenzyme a (see paper)
28% identity, 51% coverage: 38:219/355 of query aligns to 15:211/368 of 7rytB
Sites not aligning to the query:
Q10341 Serine O-succinyltransferase; SST; EC 2.3.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
29% identity, 52% coverage: 29:213/355 of query aligns to 70:276/504 of Q10341
Sites not aligning to the query:
5w8oB Homoserine transacetylase metx from mycobacterium hassiacum (see paper)
27% identity, 49% coverage: 41:213/355 of query aligns to 9:189/346 of 5w8oB
6ioiA Crystal structure of homoserine o-acetyltransferase in complex with coa from mycobacterium smegmatis atcc 19420 (see paper)
28% identity, 53% coverage: 26:213/355 of query aligns to 1:206/366 of 6ioiA
Sites not aligning to the query:
6iohA Crystal structure of homoserine o-acetyltransferase in complex with homoserine from mycobacterium smegmatis atcc 19420 (see paper)
28% identity, 53% coverage: 26:213/355 of query aligns to 1:206/375 of 6iohA
Sites not aligning to the query:
7ondA Halotag engineering for enhanced fluorogenicity and kinetics with a styrylpyridine dye (see paper)
32% identity, 40% coverage: 41:182/355 of query aligns to 8:135/296 of 7ondA
Sites not aligning to the query:
6u2mA Crystal structure of a halotag-based calcium indicator, halocamp v2, bound to jf635 (see paper)
32% identity, 40% coverage: 41:182/355 of query aligns to 183:310/464 of 6u2mA
Sites not aligning to the query:
7zizA X-ray structure of the dead variant haloalkane dehalogenase halotag7- d106a bound to a pentanol tetramethylrhodamine ligand (tmr-hy5) (see paper)
31% identity, 40% coverage: 41:182/355 of query aligns to 8:135/293 of 7zizA
Sites not aligning to the query:
>Ac3H11_3736 FitnessBrowser__acidovorax_3H11:Ac3H11_3736
MTLSFWRNAFAPMLLGVLATGSSAAADYPTPKHGEWVVKDFRFHTGQTLPELKLAYSTVG
EPTGEPVLVLHGTNGSAESMLTPGFAGTLFGPGQPLDARKHFIILPDAIGTGRSSKPSDG
LRAAFPAYNYDDVVQAQYRLLTEHLGVRHVRAIIGNSMGGMHTWVWAQRYPDFMDIAVPM
ASLPAAMSGRNWMMRRLLVEAIRNDPEWQGGNYTRQPRSLQFASVFFGTGTNGGHQGLQK
LAPNRVAADALVEQRLKAPFRGDANDHIYQWEASRDYDPEPGLERITARVLAINSADDER
NPPELGVLDKAIARIPHAQAYVIPASADTLGHSTVGLARFYQDRLAQVLANAPRR
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory