SitesBLAST – Find functional sites

 

SitesBLAST

Comparing Ac3H11_3954 hypothetical protein, not 6-phosphogluconolactonase to proteins with known functional sites using BLASTp with E ≤ 0.001.

Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures

Found 1 hits to proteins with known functional sites (download)

P52697 6-phosphogluconolactonase; 6-P-gluconolactonase; Pgl; EC 3.1.1.31 from Escherichia coli (strain K12) (see paper)
32% identity, 96% coverage: 7:336/343 of query aligns to 5:328/331 of P52697

query
sites
P52697
V
 
V
F
 
Y
V
 
I
S
 
A
C
 
S
A
 
P
D
 
E
S
 
S
G
 
Q
E
 
Q
L
 
I
H
 
H
V
 
V
L
 
W
H
 
N
L
 
L
S
 
N
S
 
H
E
 
E
T
 
-
G
 
G
L
 
A
L
 
L
R
 
T
T
 
L
E
 
T
Q
 
Q
V
 
V
L
 
V
A
 
D
L
 
V
G
 
P
G
 
G
Q
 
Q
L
 
V
M
 
Q
P
 
P
M
 
M
A
 
V
L
 
V
S
 
S
P
 
P
D
 
D
G
 
K
K
 
R
R
 
Y
L
 
L
Y
 
Y
V
 
V
A
 
G
R
 
V
R
 
R
S
 
P
D
 
E
P
 
-
L
 
F
A
 
R
V
 
V
V
 
L
T
 
A
L
 
Y
A
 
R
V
 
I
D
 
A
A
 
P
R
 
D
A
 
D
G
 
G
R
 
A
A
 
L
E
 
T
V
 
F
L
 
A
G
 
A
E
 
E
A
 
S
A
 
A
L
 
L
P
 
P
A
 
G
S
 
S
M
 
P
A
 
T
H
 
H
V
 
I
A
 
S
T
 
T
D
 
D
G
 
H
T
 
Q
G
 
G
R
 
Q
W
 
F
L
 
V
L
 
F
S
 
V
A
 
G
S
 
S
Y
 
Y
G
 
N
A
 
A
D
 
G
L
 
N
V
 
V
A
 
S
V
 
V
Q
 
T
A
 
R
I
 
L
A
 
E
A
 
-
D
 
D
G
 
G
V
 
L
V
 
P
A
 
V
A
 
G
G
 
V
R
 
V
G
 
D
A
 
V
T
 
V
T
 
E
Y
 
G
A
 
L
T
 
D
G
 
G
R
 
-
H
 
-
A
 
C
H
 
H
S
 
S
A
 
A
L
 
N
A
 
I
S
 
S
P
 
P
G
 
D
N
 
N
R
 
R
F
 
T
V
 
L
L
 
W
A
 
V
A
 
P
S
 
A
L
 
L
G
 
K
G
 
Q
G
 
D
Q
 
R
L
 
I
H
 
C
R
 
L
Y
 
F
R
 
T
F
 
V
D
 
-
A
 
S
A
 
D
T
 
D
G
 
G
A
 
H
L
 
L
Q
 
V
P
 
A
T
 
Q
D
 
D
P
 
P
A
 
A
V
 
E
F
 
V
A
 
T
L
 
T
P
 
V
A
 
E
G
 
G
T
 
A
G
 
G
P
 
P
R
 
R
H
 
H
L
 
M
R
 
V
F
 
F
N
 
H
A
 
P
R
 
N
G
 
E
D
 
Q
R
 
Y
I
 
A
Y
 
Y
L
 
C
L
 
V
G
 
N
E
 
E
L
 
L
D
 
N
A
 
S
C
 
S
V
 
V
H
 
D
V
 
V
L
 
W
G
 
E
W
 
L
D
 
K
E
 
D
A
 
P
S
 
H
G
 
G
G
 
N
L
 
I
E
 
E
L
 
C
L
 
V
Q
 
Q
S
 
T
L
 
L
P
 
D
T
 
M
L
 
M
P
 
P
P
 
E
G
 
N
S
 
F
T
 
S
G
 
D
P
 
T
A
 
R
W
 
W
G
 
A
A
 
A
D
 
D
L
 
I
H
 
H
L
 
I
S
 
T
A
 
P
D
 
D
G
 
G
H
 
R
W
 
H
L
 
L
Y
 
Y
T
 
A
S
 
C
E
 
D
R
 
R
N
 
T
S
 
A
H
 
S
T
 
L
L
 
I
A
 
T
G
 
V
F
 
F
A
 
S
V
 
V
D
 
S
A
 
E
V
 
D
T
 
G
G
 
S
R
 
V
L
 
L
A
 
S
P
 
K
I
 
E
D
 
G
Y
 
F
W
 
Q
S
 
P
T
 
T
Q
 
E
L
 
T
Q
 
Q
P
 
P
R
 
R
G
 
G
F
 
F
V
 
N
I
 
V
T
 
D
P
 
H
D
 
S
G
 
G
R
x
K
H
 
Y
L
 
L
I
 
I
A
 
A
A
 
A
G
 
G
Q
 
Q
I
 
K
S
 
S
H
 
H
R
 
H
V
 
I
G
 
S
V
 
V
H
 
Y
L
 
E
I
 
I
A
 
V
P
 
G
G
 
E
S
 
Q
G
 
G
A
 
L
L
 
L
T
 
H
Q
 
E
V
 
K
A
 
G
E
 
R
H
 
Y
D
 
A
V
 
V
G
 
G
L
 
Q
N
 
G
P
 
P
N
 
M
W
 
W
I
 
V
T
 
V
V
 
V

Query Sequence

>Ac3H11_3954 hypothetical protein, not 6-phosphogluconolactonase
MDNDTLVFVSCADSGELHVLHLSSETGLLRTEQVLALGGQLMPMALSPDGKRLYVARRSD
PLAVVTLAVDARAGRAEVLGEAALPASMAHVATDGTGRWLLSASYGADLVAVQAIAADGV
VAAGRGATTYATGRHAHSALASPGNRFVLAASLGGGQLHRYRFDAATGALQPTDPAVFAL
PAGTGPRHLRFNARGDRIYLLGELDACVHVLGWDEASGGLELLQSLPTLPPGSTGPAWGA
DLHLSADGHWLYTSERNSHTLAGFAVDAVTGRLAPIDYWSTQLQPRGFVITPDGRHLIAA
GQISHRVGVHLIAPGSGALTQVAEHDVGLNPNWITVLPMQPDA

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory