SitesBLAST

P00099 Cytochrome c-551; Cytochrome C8; Cytochrome c551 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 4 papers)
52% identity, 97% coverage: 4:101/101 of query aligns to 8:104/104 of P00099

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P00099

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23:104 (vs. 19:101, 57% identical) modified: mature protein, Cytochrome c-551
H38 (= H34) binding axial binding residue
M83 (= M79) binding axial binding residue

Sites not aligning to the query:

1:22 signal peptide

351cA Structure of cytochrome c551 from p. Aeruginosa refined at 1.6 angstroms resolution and comparison of the two redox forms (see paper)
60% identity, 77% coverage: 24:101/101 of query aligns to 6:82/82 of 351cA

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351cA

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binding protoporphyrin ix containing fe: C12 (= C30), C15 (= C33), H16 (= H34), G24 (= G42), P25 (= P43), Y27 (= Y45), L44 (= L62), R47 (≠ K65), I48 (= I66), Q53 (≠ S71), G54 (= G72), V55 (= V73), W56 (= W74), G57 (= G75), I59 (≠ V77), P60 (= P78), M61 (= M79)

1corA Investigation of the solution conformation of cytochromE C-551 from pseudomonas stutzeri (see paper)
59% identity, 78% coverage: 23:101/101 of query aligns to 5:82/82 of 1corA

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1corA

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binding heme c: K10 (= K28), C12 (= C30), C15 (= C33), H16 (= H34), V23 (= V41), G24 (= G42), P25 (= P43), L44 (= L62), H47 (≠ K65), I48 (= I66), S52 (≠ G70), Q53 (≠ S71), G54 (= G72), V55 (= V73), W56 (= W74), G57 (= G75), I59 (≠ V77), M61 (= M79), N64 (= N82)

1a56A Primary sequence and solution conformation of ferricytochromE C-552 from nitrosomonas europaea, nmr, mean structure refined with explicit hydrogen bond constraints (see paper)
59% identity, 80% coverage: 21:101/101 of query aligns to 1:81/81 of 1a56A

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1a56A

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binding heme c: N9 (= N29), C10 (= C30), C13 (= C33), H14 (= H34), V21 (= V41), G22 (= G42), P23 (= P43), K45 (= K65), I46 (= I66), S50 (≠ G70), W54 (= W74), Q56 (≠ P76), I57 (≠ V77), M59 (= M79), N62 (= N82), V63 (≠ A83), N64 (≠ Q84)

5xecC Heterodimer constructed from pa cyt c551-ht cyt c552 and ht cyt c552- pa cyt c551 chimeric proteins (see paper)
60% identity, 77% coverage: 24:101/101 of query aligns to 4:80/80 of 5xecC

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binding heme c: C10 (= C30), C13 (= C33), H14 (= H34), P23 (= P43), Y25 (= Y45), L42 (= L62), R45 (≠ K65), Q51 (≠ S71), V53 (= V73), W54 (= W74), G55 (= G75), I57 (≠ V77), M59 (= M79), N62 (= N82)

5aurA Hydrogenobacter thermophilus cytochrome c552 dimer formed by domain swapping at n-terminal region (see paper)
64% identity, 77% coverage: 24:101/101 of query aligns to 4:83/83 of 5aurA

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5aurA

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binding heme c: C10 (= C30), C13 (= C33), H14 (= H34), P26 (= P43), Y28 (= Y45), Y35 (= Y52), Y44 (≠ K61), I49 (= I66), S54 (= S71), G55 (= G72), V56 (= V73), W57 (= W74), G58 (= G75), V60 (= V77), P61 (= P78), M62 (= M79), Q65 (≠ N82)

6kq1A Crystal structure of cytochrome c551 from pseudomonas sp. Strain mt-1.
57% identity, 78% coverage: 23:101/101 of query aligns to 5:82/82 of 6kq1A

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binding heme c: C12 (= C30), C15 (= C33), H16 (= H34), G24 (= G42), P25 (= P43), V30 (= V48), Y34 (= Y52), L44 (= L62), H47 (≠ K65), I48 (= I66), Q53 (≠ S71), G54 (= G72), N55 (≠ V73), W56 (= W74), G57 (= G75), I59 (≠ V77), M61 (= M79), N64 (= N82)
binding zinc ion: K10 (= K28), E70 (≠ D89)

Sites not aligning to the query:

binding zinc ion: 2, 4

1cchA The solution conformation of cytochromE C-551 from p.Stutzeri zobell determined by nmr+ (see paper)
57% identity, 78% coverage: 23:101/101 of query aligns to 5:82/82 of 1cchA

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1cchA

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binding heme c: C12 (= C30), C15 (= C33), H16 (= H34), L44 (= L62), H47 (≠ K65), I48 (= I66), S52 (≠ G70), Q53 (≠ S71), V55 (= V73), W56 (= W74), G57 (= G75), I59 (≠ V77), M61 (= M79), P62 (= P80), N64 (= N82)

4xxlA Crystal structure of class 1 cytochrome mtod from sideroxydans lithotrophicus es-1 (see paper)
36% identity, 76% coverage: 23:99/101 of query aligns to 9:89/92 of 4xxlA

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binding heme c: C16 (= C30), C19 (= C33), H20 (= H34), G28 (= G42), P29 (= P43), Y31 (= Y45), K37 (= K51), Y38 (= Y52), H51 (≠ K65), A58 (≠ G72), K59 (≠ V73), H68 (≠ N82)

Query Sequence

>Ac3H11_952 FitnessBrowser__acidovorax_3H11:Ac3H11_952
MKRTLITLAMTLSVAAPAMADMALATSKNCMACHAVDKKLVGPSYKDVAAKYAGQKDAVD
KLAAKIVKGGSGVWGPVPMPANAQVNDADAKKLAAWVLTQK

Or try a new SitesBLAST search

SitesBLAST's Database

SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory