Comparing BPHYT_RS00910 FitnessBrowser__BFirm:BPHYT_RS00910 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 3 hits to proteins with known functional sites (download)
O87170 2-pyrone-4,6-dicarboxylate hydrolase; PDC hydrolase; 2-pyrone-4,6-dicarboxylate lactonase; EC 3.1.1.57 from Sphingobium sp. (strain NBRC 103272 / SYK-6) (see paper)
35% identity, 93% coverage: 20:284/286 of query aligns to 15:289/293 of O87170
4di8A Crystal structure of the d248a mutant of 2-pyrone-4,6-dicarboxylic acid hydrolase from sphingomonas paucimobilis complexed with substrate at ph 8.5 (see paper)
34% identity, 93% coverage: 20:284/286 of query aligns to 16:290/294 of 4di8A
A9CEQ7 D-galactarolactone isomerase; GLI; Galactaro delta-lactone isomerase; EC 5.4.1.4 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
27% identity, 92% coverage: 22:283/286 of query aligns to 13:284/292 of A9CEQ7
>BPHYT_RS00910 FitnessBrowser__BFirm:BPHYT_RS00910
MTANRTPPRANPLGARRDTSRPGFPIPAGACDSHMHIVGPFDRYPLRETRSLEPPESTFA
DYLEMKRATGIERNVIVQPSFFAKDNACTLDSTERMGEHARAVVVVEPDVDEATLADMHA
RGARGVRLQRVVAGGTSTEQIAEMASRIRDFGWHLQLFVDSDDVEELAEQLHRLPVPVVF
DHMAHVYKESPISSRGFRTLLDLLASGKAWVKLSAWRFSPDNARARQLVDANPERVLWGS
DWPHVSYEEDVPDDGKLLDRLATWAQDSATIQRILVDNPAELYFRC
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory