Comparing BPHYT_RS02045 FitnessBrowser__BFirm:BPHYT_RS02045 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
Q8ZKR2 Aminoimidazole riboside kinase; AIRs kinase; EC 2.7.1.223 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
32% identity, 89% coverage: 17:288/305 of query aligns to 11:283/319 of Q8ZKR2
Sites not aligning to the query:
1tz3A Crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside (see paper)
32% identity, 89% coverage: 17:288/305 of query aligns to 7:272/299 of 1tz3A
1tz6A Crystal structure of aminoimidazole riboside kinase from salmonella enterica complexed with aminoimidazole riboside and atp analog (see paper)
32% identity, 89% coverage: 17:288/305 of query aligns to 7:272/297 of 1tz6A
Sites not aligning to the query:
4wjmA Crystal structure of fructokinase from brucella abortus 2308 with bound amppnp
32% identity, 81% coverage: 18:265/305 of query aligns to 17:265/312 of 4wjmA
Sites not aligning to the query:
5eynA Crystal structure of fructokinase from vibrio cholerae o395 in fructose, adp, beryllium trifluoride and calcium ion bound form
31% identity, 91% coverage: 17:293/305 of query aligns to 8:291/306 of 5eynA
5yggA Crystal structure of fructokinase double-mutant (t261c-h108c) from vibrio cholerae o395 in fructose, adp and potassium ion bound form (see paper)
30% identity, 91% coverage: 17:293/305 of query aligns to 12:295/310 of 5yggA
Q53W83 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
29% identity, 89% coverage: 36:305/305 of query aligns to 33:301/309 of Q53W83
1v1aA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound 2- keto-3-deoxygluconate and adp (see paper)
29% identity, 89% coverage: 36:305/305 of query aligns to 33:301/301 of 1v1aA
Sites not aligning to the query:
1v1bA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound atp (see paper)
29% identity, 88% coverage: 36:304/305 of query aligns to 33:300/300 of 1v1bA
3ih0A Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with amp-pnp
25% identity, 94% coverage: 15:302/305 of query aligns to 5:294/304 of 3ih0A
3gbuA Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with atp
24% identity, 94% coverage: 15:302/305 of query aligns to 4:293/302 of 3gbuA
3lkiB Crystal structure of fructokinase with bound atp from xylella fastidiosa
30% identity, 90% coverage: 31:305/305 of query aligns to 24:317/322 of 3lkiB
7fcaD Pfkb(mycobacterium marinum) (see paper)
37% identity, 44% coverage: 131:265/305 of query aligns to 107:240/282 of 7fcaD
Sites not aligning to the query:
3uqdB Crystal structure of the phosphofructokinase-2 from escherichia coli in complex with substrates and products (see paper)
30% identity, 38% coverage: 186:300/305 of query aligns to 182:299/309 of 3uqdB
Sites not aligning to the query:
3uqdA Crystal structure of the phosphofructokinase-2 from escherichia coli in complex with substrates and products (see paper)
30% identity, 38% coverage: 186:300/305 of query aligns to 182:299/309 of 3uqdA
Sites not aligning to the query:
3n1cA Crystal structure of the phosphofructokinase-2 from escherichia coli in complex with fructose-6-phosphate (see paper)
30% identity, 38% coverage: 186:300/305 of query aligns to 182:299/309 of 3n1cA
Sites not aligning to the query:
P06999 ATP-dependent 6-phosphofructokinase isozyme 2; ATP-PFK 2; Phosphofructokinase 2; 6-phosphofructokinase isozyme II; Phosphohexokinase 2; EC 2.7.1.11 from Escherichia coli (strain K12) (see 3 papers)
30% identity, 38% coverage: 186:300/305 of query aligns to 182:299/309 of P06999
Sites not aligning to the query:
8cqxA Ribokinase from t.Sp mutant a92g
29% identity, 90% coverage: 31:305/305 of query aligns to 31:298/300 of 8cqxA
3cqdA Structure of the tetrameric inhibited form of phosphofructokinase-2 from escherichia coli (see paper)
31% identity, 34% coverage: 186:290/305 of query aligns to 182:292/304 of 3cqdA
Sites not aligning to the query:
3uqeA Crystal structure of the phosphofructokinase-2 mutant y23d from escherichia coli
30% identity, 34% coverage: 186:290/305 of query aligns to 182:295/307 of 3uqeA
>BPHYT_RS02045 FitnessBrowser__BFirm:BPHYT_RS02045
MSNQSANHEFPFFVSAGDILTDLVRTGASQWLSRPGGAGWNVARCVARLGLPTACAGSLG
VDNFSDELWNASVAAGLDMRFMQRVERPPLLAIVHQTHPPAYFFMGENSADLAFDPAQLP
AGWMGQVKWAHFGCISLVRQPIGNTLATLAAELRSQGVKISFDPNYRNLMEHGYEPTLRK
MAALADLIKVSDEDLRLIFKTDDEAGALAQLRAMNPAATVLVTRGPETAVLIDGAMVTEA
RPPRVEVVDTVGAGDASIGGLLFSLMTAPQRAWPEHLAFALAAGAAACRHAGAHAPSLDE
VVALL
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory