Comparing BPHYT_RS02895 FitnessBrowser__BFirm:BPHYT_RS02895 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 6 hits to proteins with known functional sites (download)
O31645 PTS system mannose-specific EIIBCA component; EIIBCA-Man; EII-Man; EC 2.7.1.191 from Bacillus subtilis (strain 168) (see 2 papers)
32% identity, 73% coverage: 39:148/151 of query aligns to 538:648/650 of O31645
Sites not aligning to the query:
C0H3V2 Mannitol-specific phosphotransferase enzyme IIA component; EIIA; EIII; PTS system mannitol-specific EIIA component from Bacillus subtilis (strain 168) (see paper)
29% identity, 95% coverage: 6:148/151 of query aligns to 2:141/143 of C0H3V2
O31644 Transcriptional regulator ManR; Mannose operon transcriptional activator; EC 2.7.1.191 from Bacillus subtilis (strain 168) (see paper)
29% identity, 68% coverage: 22:123/151 of query aligns to 526:623/648 of O31644
Sites not aligning to the query:
P00550 PTS system mannitol-specific EIICBA component; EIICBA-Mtl; EII-Mtl; EC 2.7.1.197 from Escherichia coli (strain K12) (see 2 papers)
25% identity, 91% coverage: 8:145/151 of query aligns to 496:633/637 of P00550
Sites not aligning to the query:
8gvhA Human ae2 in acidic kno3 (see paper)
32% identity, 55% coverage: 60:142/151 of query aligns to 129:213/788 of 8gvhA
Sites not aligning to the query:
1j6tA Complex of enzyme iiamtl and the histidine-containing phosphocarrier protein hpr from escherichia coli nmr, restrained regularized mean structure (see paper)
26% identity, 91% coverage: 8:145/151 of query aligns to 4:141/144 of 1j6tA
>BPHYT_RS02895 FitnessBrowser__BFirm:BPHYT_RS02895
MNRLAKFLPLENVVVGLSVTSKKRVFEQAGLIFENQNGIARSTVTDNLFARERLGSTGLG
EGVAIPHGRIKGLKQPLAAFVRLAEPIPFESPDGQPVSLLIFLLVPEQATQQHLEILSEI
AQLLSDREARERLHTEEDRESLHRLLTQWQP
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory