Comparing BPHYT_RS13720 FitnessBrowser__BFirm:BPHYT_RS13720 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
7kb1C Complex of o-acety-l-homoserine aminocarboxypropyltransferase (mety) from thermotoga maritima and a key reaction intermediate (see paper)
49% identity, 94% coverage: 6:427/450 of query aligns to 7:428/428 of 7kb1C
7kb1A Complex of o-acety-l-homoserine aminocarboxypropyltransferase (mety) from thermotoga maritima and a key reaction intermediate (see paper)
49% identity, 94% coverage: 6:427/450 of query aligns to 7:428/428 of 7kb1A
8wkoA Crystal structure of o-acetylhomoserine sulfhydrylase from lactobacillus plantarum in the closed form
50% identity, 93% coverage: 6:422/450 of query aligns to 9:422/425 of 8wkoA
8erbK Crystal structure of fub7 in complex with vinylglycine ketimine (see paper)
50% identity, 94% coverage: 4:425/450 of query aligns to 4:427/429 of 8erbK
8erjB Crystal structure of fub7 in complex with e-2-aminocrotonate (see paper)
50% identity, 94% coverage: 4:425/450 of query aligns to 3:426/428 of 8erjB
8erjA Crystal structure of fub7 in complex with e-2-aminocrotonate (see paper)
50% identity, 94% coverage: 4:425/450 of query aligns to 3:426/428 of 8erjA
O13326 Homocysteine synthase; O-acetylhomoserine sulfhydrylase; OAH SHL; OAH sulfhydrylase; EC 2.5.1.49 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
49% identity, 94% coverage: 1:425/450 of query aligns to 3:429/429 of O13326
2ctzA Crystal structure of o-acetyl homoserine sulfhydrylase from thermus thermophilus hb8
48% identity, 93% coverage: 5:422/450 of query aligns to 2:420/421 of 2ctzA
Q5SK88 O-acetyl-L-homoserine sulfhydrylase 1; OAH-sulfhydrylase 1; EC 2.5.1.- from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)
48% identity, 93% coverage: 5:422/450 of query aligns to 2:420/421 of Q5SK88
4omaA The crystal structure of methionine gamma-lyase from citrobacter freundii in complex with l-cycloserine pyridoxal-5'-phosphate (see paper)
39% identity, 93% coverage: 6:425/450 of query aligns to 8:395/396 of 4omaA
3jwbA Crystal structure of l-methionine gamma-lyase from citrobacter freundii with norleucine (see paper)
39% identity, 93% coverage: 6:425/450 of query aligns to 8:395/396 of 3jwbA
3jwaA Crystal structure of l-methionine gamma-lyase from citrobacter freundii with methionine phosphinate (see paper)
39% identity, 93% coverage: 6:425/450 of query aligns to 8:395/396 of 3jwaA
3jw9A Crystal structure of l-methionine gamma-lyase from citrobacter freundii with s-ethyl-cysteine (see paper)
39% identity, 93% coverage: 6:425/450 of query aligns to 8:395/396 of 3jw9A
6egrA Crystal structure of citrobacter freundii methionine gamma-lyase with v358y replacement (see paper)
39% identity, 93% coverage: 6:425/450 of query aligns to 8:395/396 of 6egrA
5m3zA Crystal structure of citrobacter freundii methionine gamma-lyase with c115h replacement in the complex with l-norleucine (see paper)
39% identity, 93% coverage: 6:425/450 of query aligns to 7:394/395 of 5m3zA
4hf8A Crystal structure of l-methionine gamma-lyase from citrobacter freundii with glycine (see paper)
39% identity, 93% coverage: 6:425/450 of query aligns to 8:395/396 of 4hf8A
3mkjA Methionine gamma-lyase from citrobacter freundii with pyridoximine-5'- phosphate (see paper)
38% identity, 93% coverage: 6:425/450 of query aligns to 8:384/386 of 3mkjA
5x2xA Crystal structure of pseudomonas putida methionine gamma-lyase wild type with l-homocysteine intermediates (see paper)
41% identity, 93% coverage: 6:425/450 of query aligns to 4:391/392 of 5x2xA
5x2wA Crystal structure of pseudomonas putida methionine gamma-lyase wild type with l-methionine intermediates (see paper)
41% identity, 93% coverage: 6:425/450 of query aligns to 4:391/392 of 5x2wA
1pg8A Crystal structure of l-methionine alpha-, gamma-lyase
41% identity, 93% coverage: 6:425/450 of query aligns to 10:397/398 of 1pg8A
>BPHYT_RS13720 FitnessBrowser__BFirm:BPHYT_RS13720
MSANRFDTLALHAGAAPDPTTGARATPIYQTTSFSFRDSDHAAALFNMERAGHVYSRISN
PTVAVFEERVAALENGAGAIGTASGQAALHLAIATLMGAGSHIVASSALYGGSHNLLHYT
LRRFGIETTFVKPGDLDAWRAALRPNTRLLFGETLGNPGLDVLDIAAVAQIAHEHRVPLL
VDSTFTTPYLLKPFEHGADFVYHSATKFLGGHGTTIGGVLVDGGTFDFEASGRFPEFTEP
YDGFHGMVFSEESTVAPFLLRARREGLRDFGACLHPQAAWQLLQGIETLPLRMERHVANT
RRVVEFLAAHAAVESVAYPELPTHPDHALAKRLLPRGAGAVFSFNLRGDRAAGRSFIEAL
SLFSHLANVGDARSLVIHPASTTHFRMDAAALAAAGIAEGTIRLSIGLEDPDDLIDDLKR
ALKAAQKASASSAPHGGAAAAAAQTRPESA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory