Comparing BPHYT_RS14005 FitnessBrowser__BFirm:BPHYT_RS14005 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
2ia4B Crystal structure of novel amino acid binding protein from shigella flexneri
49% identity, 92% coverage: 23:292/292 of query aligns to 8:278/278 of 2ia4B
2vhaA Debp (see paper)
50% identity, 92% coverage: 23:291/292 of query aligns to 7:276/276 of 2vhaA
8ovoA X-ray structure of the sf-iglusnfr-s72a in complex with l-aspartate
48% identity, 83% coverage: 23:264/292 of query aligns to 5:247/503 of 8ovoA
6svfA Crystal structure of the p235gk mutant of argbp from t. Maritima (see paper)
28% identity, 82% coverage: 24:262/292 of query aligns to 3:229/229 of 6svfA
2yjpA Crystal structure of the solute receptors for l-cysteine of neisseria gonorrhoeae (see paper)
26% identity, 82% coverage: 21:258/292 of query aligns to 1:229/247 of 2yjpA
4zv1A An ancestral arginine-binding protein bound to arginine (see paper)
26% identity, 80% coverage: 28:260/292 of query aligns to 1:225/226 of 4zv1A
1xt8B Crystal structure of cysteine-binding protein from campylobacter jejuni at 2.0 a resolution (see paper)
26% identity, 84% coverage: 23:267/292 of query aligns to 6:237/251 of 1xt8B
5eyfB Crystal structure of solute-binding protein from enterococcus faecium with bound glutamate
27% identity, 78% coverage: 33:260/292 of query aligns to 15:234/243 of 5eyfB
4zv2A An ancestral arginine-binding protein bound to glutamine (see paper)
25% identity, 80% coverage: 28:262/292 of query aligns to 1:225/225 of 4zv2A
6h20A Glnh bound to asn, mycobacterium tuberculosis (see paper)
26% identity, 88% coverage: 9:266/292 of query aligns to 29:281/287 of 6h20A
6h1uA Glnh bound to asp, mycobacterium tuberculosis (see paper)
26% identity, 88% coverage: 9:266/292 of query aligns to 29:281/287 of 6h1uA
6h2tA Glnh bound to glu, mycobacterium tuberculosis (see paper)
26% identity, 88% coverage: 9:266/292 of query aligns to 30:282/288 of 6h2tA
5t0wA Crystal structure of the ancestral amino acid-binding protein anccdt- 1, a precursor of cyclohexadienyl dehydratase
26% identity, 82% coverage: 23:260/292 of query aligns to 2:228/229 of 5t0wA
8eyzA Engineered glutamine binding protein bound to gln and a cobaloxime ligand (see paper)
24% identity, 80% coverage: 30:263/292 of query aligns to 2:225/226 of 8eyzA
4ymxA Crystal structure of the substrate binding protein of an amino acid abc transporter (see paper)
23% identity, 79% coverage: 31:262/292 of query aligns to 1:224/224 of 4ymxA
3k4uE Crystal structure of putative binding component of abc transporter from wolinella succinogenes dsm 1740 complexed with lysine
24% identity, 79% coverage: 31:261/292 of query aligns to 4:227/234 of 3k4uE
4i62A 1.05 angstrom crystal structure of an amino acid abc transporter substrate-binding protein abpa from streptococcus pneumoniae canada mdr_19a bound to l-arginine
24% identity, 83% coverage: 24:264/292 of query aligns to 1:235/237 of 4i62A
2v25A Structure of the campylobacter jejuni antigen peb1a, an aspartate and glutamate receptor with bound aspartate (see paper)
20% identity, 82% coverage: 22:259/292 of query aligns to 1:229/231 of 2v25A
2pyyB Crystal structure of the glur0 ligand-binding core from nostoc punctiforme in complex with (l)-glutamate (see paper)
27% identity, 57% coverage: 94:260/292 of query aligns to 53:210/217 of 2pyyB
Sites not aligning to the query:
4ohnA Crystal structure of an abc uptake transporter substrate binding protein from streptococcus pneumoniae with bound histidine
24% identity, 61% coverage: 88:265/292 of query aligns to 64:244/246 of 4ohnA
Sites not aligning to the query:
>BPHYT_RS14005 FitnessBrowser__BFirm:BPHYT_RS14005
MALTTFGAASLACSAQTDELTGTLRKIHDDGVVVLGVREASIPFSYFDGKGTVGYSQTIA
LQIVEEIKKTLGMPQLKVHEITVTSSNRTPMLLNNQIDLECGSTTHTVERENLAAFSNSF
FQYAVRMIARKNAGITDFQDLAGKAVVTTAGTSDERLLRRLNTDKLLNMRITSARDHSEA
FNTLKDGRAVAFVMDEPIVYGFKSTDPRPDDFVVTGTPLGYEVYACMFRKGDEPFRTLVN
GVIARGQTSGEAERLYRQWFTQPIPPHGINLNFPLSEQNRALFAHPNDRALD
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory