Comparing BPHYT_RS16025 FitnessBrowser__BFirm:BPHYT_RS16025 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 10 hits to proteins with known functional sites (download)
B4E9I9 Kynurenine formamidase; KFA; KFase; Arylformamidase; N-formylkynurenine formamidase; FKF; EC 3.5.1.9 from Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)) (see paper)
81% identity, 99% coverage: 1:209/212 of query aligns to 1:209/213 of B4E9I9
4cogA Crystal structure of kynurenine formamidase from burkholderia cenocepacia (see paper)
81% identity, 98% coverage: 3:209/212 of query aligns to 1:207/207 of 4cogA
Q9I234 Kynurenine formamidase; KFA; KFase; Arylformamidase; N-formylkynurenine formamidase; FKF; EC 3.5.1.9 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
68% identity, 98% coverage: 5:212/212 of query aligns to 7:213/213 of Q9I234
4cobA Crystal structure kynurenine formamidase from pseudomonas aeruginosa (see paper)
69% identity, 97% coverage: 5:209/212 of query aligns to 3:206/206 of 4cobA
Q81PP9 Kynurenine formamidase; KFA; KFase; Arylformamidase; N-formylkynurenine formamidase; FKF; EC 3.5.1.9 from Bacillus anthracis (see paper)
40% identity, 95% coverage: 6:206/212 of query aligns to 8:207/209 of Q81PP9
4cz1A Crystal structure of kynurenine formamidase from bacillus anthracis complexed with 2-aminoacetophenone. (see paper)
40% identity, 95% coverage: 6:206/212 of query aligns to 6:205/207 of 4cz1A
4co9A Crystal structure of kynurenine formamidase from bacillus anthracis (see paper)
40% identity, 95% coverage: 6:206/212 of query aligns to 6:205/207 of 4co9A
1r61A The structure of predicted metal-dependent hydrolase from bacillus stearothermophilus
28% identity, 95% coverage: 4:205/212 of query aligns to 5:202/205 of 1r61A
8hmoA Crystal structure of metal-dependent hydrolase complexed with manganese from bacillus smithii
27% identity, 92% coverage: 11:205/212 of query aligns to 4:200/205 of 8hmoA
8f9xA Cyclase-pte
36% identity, 36% coverage: 6:82/212 of query aligns to 9:84/230 of 8f9xA
Sites not aligning to the query:
>BPHYT_RS16025 FitnessBrowser__BFirm:BPHYT_RS16025
MPTLWDITPAVDTATPVWPGDTPVGIERVWRMEAGSPVNVARLTLSPHTGAHTDAPLHYD
AEGVAIGEVPLDAYLGRCRVIHCIGASPVVTPQHLSGSLDDLPPRVLLRTYRNAPTAAWD
SAFCAVAPDTIDLLAARGVKLIGIDTPSLDPQESKTMDAHHRIRTHRMAILEGIVLDDVA
PGDYELIALPLKLTTLDASPVRAILRALPESQ
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory