Comparing BPHYT_RS16490 FitnessBrowser__BFirm:BPHYT_RS16490 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 7 hits to proteins with known functional sites (download)
2r46A Crystal structure of escherichia coli glycerol-3-phosphate dehydrogenase in complex with 2-phosphopyruvic acid. (see paper)
50% identity, 89% coverage: 30:482/509 of query aligns to 27:475/495 of 2r46A
Sites not aligning to the query:
2r45A Crystal structure of escherichia coli glycerol-3-phosphate dehydrogenase in complex with 2-phospho-d-glyceric acid (see paper)
50% identity, 89% coverage: 30:482/509 of query aligns to 27:475/495 of 2r45A
Sites not aligning to the query:
2qcuB Crystal structure of glycerol-3-phosphate dehydrogenase from escherichia coli (see paper)
50% identity, 89% coverage: 30:482/509 of query aligns to 27:475/501 of 2qcuB
Sites not aligning to the query:
2rgoA Structure of alpha-glycerophosphate oxidase from streptococcus sp.: A template for the mitochondrial alpha-glycerophosphate dehydrogenase (see paper)
32% identity, 94% coverage: 29:507/509 of query aligns to 41:539/557 of 2rgoA
Sites not aligning to the query:
Q9SS48 Glycerol-3-phosphate dehydrogenase SDP6, mitochondrial; Protein SUGAR-DEPENDENT 6; EC 1.1.5.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
31% identity, 93% coverage: 8:482/509 of query aligns to 75:573/629 of Q9SS48
2rgoB Structure of alpha-glycerophosphate oxidase from streptococcus sp.: A template for the mitochondrial alpha-glycerophosphate dehydrogenase (see paper)
32% identity, 94% coverage: 29:507/509 of query aligns to 39:510/530 of 2rgoB
Sites not aligning to the query:
3da1A X-ray structure of the glycerol-3-phosphate dehydrogenase from bacillus halodurans complexed with fad. Northeast structural genomics consortium target bhr167.
30% identity, 93% coverage: 8:478/509 of query aligns to 20:442/496 of 3da1A
>BPHYT_RS16490 FitnessBrowser__BFirm:BPHYT_RS16490
MTQGSRYDLLVVGGGINGAGIARDAAGRGLSVLLCEQDDLAAHTSSASTKLIHGGLRYLE
YREFGLVRKALQERETLLRAAPHIMWPLRFVMPHMPDLRPAWLIRAGLFLYDHLARRELL
PGSRGIVMRNHPAGAPLVDSIKRGFVYSDGWVNDARLVVLNALDAQEHGAKILTRTKLLS
AVRAGGEWRAQLKRADGTLLDVRAASIANAAGPWVGELLQGALGRAASHSVRLVKGSHIV
TRRLFEHDHAYIFQNPDKRIIFAIPYEHDYTLIGTTDLEYRGDPSQVAINADETQYLCDS
INRYFKQKISPADVRWTYSGVRPLLEEEGADNPSAVTRDYSLELDAPAGEAPLLSVFGGK
ITTFRKLAEEAVDKLAQALQNGASSWTAGAPLPGGDIPNANFERFLSEFKQQHAWLPADL
AHRLARAYGTRVKQVLGNARSVADLGRAFAPGLYEAELTYLRDTEWARSAQDVLWRRSKL
GLHVEPGTLDSITRDIDAWFAREPAREGA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory