Comparing BPHYT_RS21415 FitnessBrowser__BFirm:BPHYT_RS21415 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 11 hits to proteins with known functional sites (download)
Q29551 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial; SCOT; 3-oxoacid CoA-transferase 1; Somatic-type succinyl-CoA:3-oxoacid CoA-transferase; SCOT-s; Succinate-coenzyme A transferase; Succinyl-CoA:3-oxoacid CoA transferase; EC 2.8.3.5 from Sus scrofa (Pig) (see 3 papers)
44% identity, 91% coverage: 4:218/235 of query aligns to 41:271/520 of Q29551
Sites not aligning to the query:
3k6mC Dynamic domains of succinyl-coa:3-ketoacid-coenzyme a transferase from pig heart. (see paper)
44% identity, 91% coverage: 4:218/235 of query aligns to 2:232/466 of 3k6mC
Sites not aligning to the query:
1o9lA Succinate:coenzyme-a transferase (pig heart)
44% identity, 91% coverage: 4:218/235 of query aligns to 2:232/468 of 1o9lA
3oxoE Succinyl-coa:3-ketoacid coa transferase from pig heart covalently bound to coa (see paper)
44% identity, 91% coverage: 4:218/235 of query aligns to 2:232/462 of 3oxoE
Sites not aligning to the query:
1k6dB Crystal structure of acetate coa-transferase alpha subunit (see paper)
46% identity, 89% coverage: 8:217/235 of query aligns to 7:214/219 of 1k6dB
8i3yD Crystal structure of asct from trypanosoma brucei in complex with succinyl-coa.
41% identity, 91% coverage: 8:221/235 of query aligns to 7:235/471 of 8i3yD
8i40A Crystal structure of asct from trypanosoma brucei in complex with coa.
41% identity, 91% coverage: 8:221/235 of query aligns to 7:235/467 of 8i40A
Sites not aligning to the query:
8i3yA Crystal structure of asct from trypanosoma brucei in complex with succinyl-coa.
41% identity, 91% coverage: 8:221/235 of query aligns to 7:235/459 of 8i3yA
Sites not aligning to the query:
Q0S7P9 Cholesterol ring-cleaving hydrolase IpdA subunit; (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA hydrolase alpha subunit; COCHEA-CoA hydrolase alpha subunit; EC 4.1.99.- from Rhodococcus jostii (strain RHA1) (see paper)
28% identity, 92% coverage: 8:224/235 of query aligns to 10:241/296 of Q0S7P9
6co9A Crystal structure of rhodococcus jostii rha1 ipdab cochea-coa complex (see paper)
28% identity, 92% coverage: 8:224/235 of query aligns to 9:240/295 of 6co9A
2ahvA Crystal structure of acyl-coa transferase from e. Coli o157:h7 (ydif)- thioester complex with coa- 1 (see paper)
27% identity, 92% coverage: 8:224/235 of query aligns to 14:255/512 of 2ahvA
Sites not aligning to the query:
>BPHYT_RS21415 FitnessBrowser__BFirm:BPHYT_RS21415
MINKIFESLQSAVADVNDGATVMIGGFGTAGMPSELIDALIEQGARELTIVNNNAGNGDI
GLAALLKAKRVRKIICSFPRQSDSYVFDALYRAGELELELVPQGNLAERIRAAGAGIGGF
FTPTGYGTKLAEGKETRLIDGRHYVLEAPLHADFALIKAYRGDRWGNLTYRKTARNFGPI
MATAAKTAIVQVSQVVPLGELDPENIVTPGIFVQRVIEVPQAAHAPMPNPHDAAA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory