Comparing BPHYT_RS21700 FitnessBrowser__BFirm:BPHYT_RS21700 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 9 hits to proteins with known functional sites (download)
6ioxA Crystal structure of porphyromonas gingivalis phosphotransacetylase in complex with acetyl-coa (see paper)
46% identity, 96% coverage: 4:332/344 of query aligns to 8:337/339 of 6ioxA
2af3C Phosphotransacetylase from methanosarcina thermophila soaked with coenzyme a (see paper)
43% identity, 95% coverage: 4:331/344 of query aligns to 4:329/332 of 2af3C
Q8ZND6 Phosphate acetyltransferase; Phosphotransacetylase; EC 2.3.1.222; EC 2.3.1.8 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
44% identity, 94% coverage: 6:329/344 of query aligns to 394:709/714 of Q8ZND6
Sites not aligning to the query:
P38503 Phosphate acetyltransferase; Phosphotransacetylase; EC 2.3.1.8 from Methanosarcina thermophila (see 2 papers)
43% identity, 95% coverage: 4:331/344 of query aligns to 5:330/333 of P38503
Sites not aligning to the query:
1xcoD Crystal structure of a phosphotransacetylase from bacillus subtilis in complex with acetylphosphate (see paper)
42% identity, 93% coverage: 9:329/344 of query aligns to 12:324/325 of 1xcoD
6zngF Maeb full-length acetyl-coa bound state (see paper)
37% identity, 91% coverage: 17:330/344 of query aligns to 439:744/753 of 6zngF
Sites not aligning to the query:
P76558 NADP-dependent malic enzyme; NADP-ME; EC 1.1.1.40 from Escherichia coli (strain K12) (see paper)
32% identity, 94% coverage: 7:330/344 of query aligns to 434:755/759 of P76558
Sites not aligning to the query:
3u9eB The crystal structure of a possible phosphate acetyl/butaryl transferase (from listeria monocytogenes egd-e) in complex with coa.
29% identity, 44% coverage: 168:317/344 of query aligns to 129:274/288 of 3u9eB
Sites not aligning to the query:
3uf6A The crystal structure of a possible phosphate acetyl/butaryl transferase (from listeria monocytogenes egd-e) in complex with cod (3'-dephosphocoenzyme a)
29% identity, 44% coverage: 168:317/344 of query aligns to 127:272/285 of 3uf6A
Sites not aligning to the query:
>BPHYT_RS21700 FitnessBrowser__BFirm:BPHYT_RS21700
MKAINRIIEQARRSPMRIVLSEAEDPRVLQAAQRATREGIARILLVGDATRIREAAAGFD
VDLSGMELVDPATSALASSYADELFALRSKKGMTLEQARKEILNPLCFANLMVRLGHADG
SVSGAVNTTADVVRTAIQIIGIAPSFKLVSSFFLMMLCEPFHTLKGGLIFSDCALVVEPD
AAQLAEIAMAAADSARSLLMDEPRVAMLSFSTSGSAHHAAVDKVVNATHIVQERRPHLAI
DGDVQLDAAIVSEIALRKVKHSQVEGHANVLVFPSLEAGNIGYKLAERIGGAKAIGPLLQ
GLRKPANDLSRGCSADDIYYVTAVTAVQAQAALTHPDALTPSHT
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory