Comparing BPHYT_RS22030 FitnessBrowser__BFirm:BPHYT_RS22030 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4fwiB Crystal structure of the nucleotide-binding domain of a dipeptide abc transporter (see paper)
33% identity, 96% coverage: 12:338/341 of query aligns to 1:310/310 of 4fwiB
Q8RDH4 Dipeptide transport ATP-binding protein DppD; EC 7.4.2.9 from Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis) (see paper)
32% identity, 96% coverage: 12:338/341 of query aligns to 2:321/326 of Q8RDH4
P0AAH4 Putrescine export system ATP-binding protein SapD from Escherichia coli (strain K12) (see paper)
33% identity, 94% coverage: 14:333/341 of query aligns to 3:321/330 of P0AAH4
P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 3 papers)
36% identity, 72% coverage: 35:280/341 of query aligns to 14:256/343 of P30750
Sites not aligning to the query:
7z15I E. Coli c-p lyase bound to a phnk/phnl dual abc dimer and adp + pi (see paper)
36% identity, 76% coverage: 14:271/341 of query aligns to 3:247/253 of 7z15I
7z18I E. Coli c-p lyase bound to a phnk abc dimer and atp (see paper)
36% identity, 76% coverage: 14:271/341 of query aligns to 3:247/250 of 7z18I
3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form (see paper)
36% identity, 72% coverage: 35:280/341 of query aligns to 15:257/344 of 3tuzC
Sites not aligning to the query:
3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form (see paper)
36% identity, 72% coverage: 35:280/341 of query aligns to 15:257/344 of 3tuiC
Sites not aligning to the query:
6cvlD Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
36% identity, 72% coverage: 35:280/341 of query aligns to 15:257/344 of 6cvlD
Sites not aligning to the query:
7z16I E. Coli c-p lyase bound to phnk/phnl dual abc dimer with amppnp and phnk e171q mutation (see paper)
35% identity, 76% coverage: 14:271/341 of query aligns to 3:247/250 of 7z16I
P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 3 papers)
35% identity, 73% coverage: 33:280/341 of query aligns to 27:261/378 of P69874
Sites not aligning to the query:
3c4jA Abc protein artp in complex with atp-gamma-s
31% identity, 76% coverage: 14:271/341 of query aligns to 3:241/242 of 3c4jA
3c41J Abc protein artp in complex with amp-pnp/mg2+
31% identity, 76% coverage: 14:271/341 of query aligns to 3:241/242 of 3c41J
2olkA Abc protein artp in complex with adp-beta-s
31% identity, 76% coverage: 14:271/341 of query aligns to 3:241/242 of 2olkA
2oljA Abc protein artp in complex with adp/mg2+
31% identity, 76% coverage: 14:271/341 of query aligns to 3:241/242 of 2oljA
4u00A Crystal structure of ttha1159 in complex with adp (see paper)
33% identity, 76% coverage: 14:271/341 of query aligns to 2:239/241 of 4u00A
1g291 Malk (see paper)
33% identity, 71% coverage: 33:273/341 of query aligns to 10:245/372 of 1g291
Sites not aligning to the query:
2d62A Crystal structure of multiple sugar binding transport atp- binding protein
32% identity, 71% coverage: 33:273/341 of query aligns to 13:248/375 of 2d62A
1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
34% identity, 66% coverage: 36:259/341 of query aligns to 15:232/353 of 1oxvD
Sites not aligning to the query:
1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
34% identity, 66% coverage: 36:259/341 of query aligns to 15:232/353 of 1oxvA
Sites not aligning to the query:
>BPHYT_RS22030 FitnessBrowser__BFirm:BPHYT_RS22030
MNTTSLANQDAATLLRVDNLKVQFGVPRGGFPWSGKATLRAVDGVSFNVRRGETVGLVGE
SGCGKSTLARAIIGLAPVASGSVRWLGDETVLPGARRNTSRLRRDVQMIFQDPLASLDPR
MTIEQIVSEPLTTHGQDVARADVQRRVLTMLERVGLNAQHLRRYPHEFSGGQCQRVGIAR
ALIGEPQLVICDEPVSALDVSIQAQIVNLLRDLQRELSLSLLFVAHDLAVVKAISHRVLV
MYLGRVMEFGDKREVYGTPRHPYTRALLSAVPVPDPVVERARRHLLLRGEIASPLNPPSG
CAFRTRCPDAIDACAREIPQPVTHGARATRVACIRVEDTVR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory