Comparing BPHYT_RS22775 FitnessBrowser__BFirm:BPHYT_RS22775 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 4 hits to proteins with known functional sites (download)
P94529 Arabinooligosaccharides transport system permease protein AraP from Bacillus subtilis (strain 168) (see paper)
31% identity, 83% coverage: 32:302/325 of query aligns to 2:288/313 of P94529
7cagA Mycobacterium smegmatis lpqy-sugabc complex in the catalytic intermediate state (see paper)
30% identity, 80% coverage: 46:306/325 of query aligns to 4:265/285 of 7cagA
P02916 Maltose/maltodextrin transport system permease protein MalF from Escherichia coli (strain K12) (see 4 papers)
23% identity, 73% coverage: 81:318/325 of query aligns to 245:507/514 of P02916
4ki0F Crystal structure of the maltose-binding protein/maltose transporter complex in an outward-facing conformation bound to maltohexaose (see paper)
24% identity, 70% coverage: 81:306/325 of query aligns to 230:480/490 of 4ki0F
>BPHYT_RS22775 FitnessBrowser__BFirm:BPHYT_RS22775
MSHSVTRHTVSGPAEPGGPGLPTPGGAVRGGKPASSRRRGPSPTARRQRRAAFLFLAPAC
VMVAIYVVWPILSTIRLSFFNWDGMSEPSFVGLANYVELFHAQTFYTALKNNLIWLLLFL
LAPPMGLAVALYLNQAVAGIRIVKSLFFAPFVLSGVVVGLIFSWFYDPTFGLLAVILGHG
VPVLGDPRYATFGIVFAALWPQTAYCMILYLTGLTSLNAEQIEAARMEGARGWSMLWHVI
LPQLRPTTFMAIVVTIIGALRSFDLISVMTGGGPFESSTVLAYYMYDQAIKYYRIGYSAA
VAVVLFAIMLVYIVYHLRRMLRAEQ
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory