Comparing BPHYT_RS23875 FitnessBrowser__BFirm:BPHYT_RS23875 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
P04983 Ribose import ATP-binding protein RbsA; EC 7.5.2.7 from Escherichia coli (strain K12) (see paper)
38% identity, 88% coverage: 39:523/549 of query aligns to 1:470/501 of P04983
P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 3 papers)
32% identity, 44% coverage: 37:280/549 of query aligns to 12:253/378 of P69874
Sites not aligning to the query:
4u00A Crystal structure of ttha1159 in complex with adp (see paper)
32% identity, 39% coverage: 41:255/549 of query aligns to 1:213/241 of 4u00A
5x40A Structure of a cbio dimer bound with amppcp (see paper)
30% identity, 42% coverage: 39:269/549 of query aligns to 1:231/280 of 5x40A
6mjpA Lptb(e163q)fgc from vibrio cholerae (see paper)
30% identity, 39% coverage: 314:529/549 of query aligns to 10:217/240 of 6mjpA
3c4jA Abc protein artp in complex with atp-gamma-s
28% identity, 43% coverage: 48:284/549 of query aligns to 9:238/242 of 3c4jA
3c41J Abc protein artp in complex with amp-pnp/mg2+
28% identity, 43% coverage: 48:284/549 of query aligns to 9:238/242 of 3c41J
2olkA Abc protein artp in complex with adp-beta-s
28% identity, 43% coverage: 48:284/549 of query aligns to 9:238/242 of 2olkA
2oljA Abc protein artp in complex with adp/mg2+
28% identity, 43% coverage: 48:284/549 of query aligns to 9:238/242 of 2oljA
P0A9R7 Cell division ATP-binding protein FtsE from Escherichia coli (strain K12) (see paper)
31% identity, 38% coverage: 48:258/549 of query aligns to 7:217/222 of P0A9R7
8w6iD Cryo-em structure of escherichia coli str k12 ftsex complex with atp- gamma-s in peptidisc
31% identity, 38% coverage: 48:258/549 of query aligns to 7:217/219 of 8w6iD
8hd0A Cell divisome spg hydrolysis machinery ftsex-envc
31% identity, 38% coverage: 48:258/549 of query aligns to 7:217/218 of 8hd0A
4ymuJ Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
29% identity, 38% coverage: 48:254/549 of query aligns to 7:212/240 of 4ymuJ
1g9xB Characterization of the twinning structure of mj1267, an atp-binding cassette of an abc transporter (see paper)
28% identity, 39% coverage: 42:255/549 of query aligns to 4:227/253 of 1g9xB
1g6hA Crystal structure of the adp conformation of mj1267, an atp-binding cassette of an abc transporter (see paper)
28% identity, 39% coverage: 42:255/549 of query aligns to 4:227/254 of 1g6hA
8tzjA Cryo-em structure of vibrio cholerae ftse/ftsx complex (see paper)
33% identity, 35% coverage: 48:239/549 of query aligns to 8:199/220 of 8tzjA
Q9BZC7 ATP-binding cassette sub-family A member 2; ATP-binding cassette transporter 2; ATP-binding cassette 2; EC 7.6.2.- from Homo sapiens (Human) (see paper)
29% identity, 39% coverage: 314:525/549 of query aligns to 2062:2262/2435 of Q9BZC7
Sites not aligning to the query:
4yerA Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
26% identity, 45% coverage: 39:283/549 of query aligns to 1:235/285 of 4yerA
P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 3 papers)
28% identity, 39% coverage: 42:255/549 of query aligns to 1:218/343 of P30750
Sites not aligning to the query:
3d31A Modbc from methanosarcina acetivorans (see paper)
30% identity, 36% coverage: 57:255/549 of query aligns to 15:205/348 of 3d31A
Sites not aligning to the query:
>BPHYT_RS23875 FitnessBrowser__BFirm:BPHYT_RS23875
MTHPASEPNPPVGGAGNVQATTGMTGAAATQAGGTTNALEPILATAGVSKTFPGVKALQR
VDFRLFPGEIHTLMGQNGAGKSTLINVLTGVLAPDEGTIRLGGELVAFASPQEAEGAGVR
TLYQEVNLCPNLSVAENIFAGRQPRRFGAIDWPDIKRRAQAALARLDVTLDVTRSLDAYP
IAVQQMVAIARALSVDARVLILDEPTSSLDDGEVSQLFKILRHLKQSGIAILFVTHFIEQ
TYAISDRITVMRNGEREGEYLARDLPADQLVSKMVGHERMSARLREAAHEGHQGHEAHAG
PQAAQAVQPFVELRGVGRRGTMQPIDLDVQPGQILGLAGLLGSGRTETARLLFGADRADS
GTILVEGRPVRLRSPRDAVRHGIGYCAEDRKKEGIVAELSIRDNILLALQARRGWWRKIS
RQRARELADLWIERLGIKAADAEQPIGLLSGGNQQKALLARWLATDPKLLILDEPTRGID
VAAKFDIMDRLLALCASGLSILFISSEISEVLRVSHRVAVLRDRRKIAEVAGKASNEDNI
YRLIAGSGE
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory