Comparing BPHYT_RS24170 BPHYT_RS24170 gluconolactonase to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 19 hits to proteins with known functional sites (download)
4gnaA Mouse smp30/gnl-xylitol complex (see paper)
31% identity, 96% coverage: 11:307/309 of query aligns to 3:297/297 of 4gnaA
4gn9A Mouse smp30/gnl-glucose complex (see paper)
31% identity, 96% coverage: 11:307/309 of query aligns to 3:297/297 of 4gn9A
4gn8A Mouse smp30/gnl-1,5-ag complex (see paper)
31% identity, 96% coverage: 11:307/309 of query aligns to 3:297/297 of 4gn8A
4gn7A Mouse smp30/gnl (see paper)
31% identity, 96% coverage: 11:307/309 of query aligns to 3:297/297 of 4gn7A
4gncA Human smp30/gnl-1,5-ag complex (see paper)
30% identity, 96% coverage: 11:307/309 of query aligns to 4:298/298 of 4gncA
3g4hA Crystal structure of human senescence marker protein-30 (zinc bound) (see paper)
30% identity, 96% coverage: 11:307/309 of query aligns to 3:297/297 of 3g4hA
Q15493 Regucalcin; RC; Gluconolactonase; GNL; Senescence marker protein 30; SMP-30; EC 3.1.1.17 from Homo sapiens (Human) (see 2 papers)
30% identity, 96% coverage: 11:307/309 of query aligns to 5:299/299 of Q15493
7pldB Caulobacter crescentus xylonolactonase with (r)-4-hydroxy-2- pyrrolidone (see paper)
32% identity, 92% coverage: 20:304/309 of query aligns to 13:285/289 of 7pldB
7plbB Caulobacter crescentus xylonolactonase with d-xylose (see paper)
32% identity, 92% coverage: 20:304/309 of query aligns to 13:285/289 of 7plbB
Q9A9Z1 D-xylonolactone lactonase; Xylono-1,5-lactonase; EC 3.1.1.110 from Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) (see paper)
32% identity, 92% coverage: 20:304/309 of query aligns to 13:285/289 of Q9A9Z1
5gx1A Luciferin-regenerating enzyme collected with serial synchrotron rotational crystallography with accumulated dose of 1.1 mgy (1st measurement) (see paper)
28% identity, 97% coverage: 7:307/309 of query aligns to 2:302/307 of 5gx1A
5d9bA Luciferin-regenerating enzyme solved by siras using xfel (refined against native data) (see paper)
28% identity, 97% coverage: 7:307/309 of query aligns to 2:302/307 of 5d9bA
3dr2A Structural and functional analyses of xc5397 from xanthomonas campestris: a gluconolactonase important in glucose secondary metabolic pathways (see paper)
27% identity, 83% coverage: 20:275/309 of query aligns to 41:288/299 of 3dr2A
3e5zA X-ray structure of the putative gluconolactonase in protein family pf08450. Northeast structural genomics consortium target drr130.
26% identity, 82% coverage: 24:275/309 of query aligns to 30:273/290 of 3e5zA
7rizA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound 2-hydroxyquinoline (see paper)
29% identity, 51% coverage: 118:275/309 of query aligns to 120:282/306 of 7rizA
Sites not aligning to the query:
7risA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound phosphate (see paper)
28% identity, 51% coverage: 118:275/309 of query aligns to 111:269/293 of 7risA
Sites not aligning to the query:
8dk0A Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound (s)gamma- valerolactone (see paper)
27% identity, 51% coverage: 118:275/309 of query aligns to 115:269/293 of 8dk0A
Sites not aligning to the query:
8djzA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound product (see paper)
27% identity, 51% coverage: 118:275/309 of query aligns to 115:269/293 of 8djzA
Sites not aligning to the query:
8djfA Crystal structure of rpa3624, a beta-propeller lactonase from rhodopseudomonas palustris, with active-site bound tetrahedral intermediate (see paper)
27% identity, 51% coverage: 118:275/309 of query aligns to 115:269/293 of 8djfA
Sites not aligning to the query:
>BPHYT_RS24170 BPHYT_RS24170 gluconolactonase
MSAAANPRVERVEAAGQAPAAVGESPVWRAAEQALYWVDIPAQKIVRLRIDSGERSEWLL
PEKVACIAFDHRGTVLAGCETGLFALTLTESAANGEAVQVTGRKLAAPDFACDDMRFNDG
RCDRQGRFWAGTMVQDMAAAKPAGALYRFDERGMLSAPVVEELITQNGLAWSPDGATMYL
SDSHPLRRQIWAFDYDIESGEPRNRRVFADLNQHAGRPDGAAVDADGCYWICANDAGLLL
RFTPEGKLDRQIAVPAIKPAMCAFGGRELDTLFVTSIRPAANASEHDGHLFAVRPGITGL
PEPEFAGEL
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory