Comparing BPHYT_RS25650 FitnessBrowser__BFirm:BPHYT_RS25650 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 12 hits to proteins with known functional sites (download)
P9WKJ5 Dihydroxy-acid dehydratase; DAD; EC 4.2.1.9 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
48% identity, 95% coverage: 6:566/588 of query aligns to 18:573/575 of P9WKJ5
6ovtA Crystal structure of ilvd from mycobacterium tuberculosis (see paper)
48% identity, 95% coverage: 6:566/588 of query aligns to 5:560/562 of 6ovtA
8hs0A The mutant structure of dhad v178w
40% identity, 96% coverage: 1:567/588 of query aligns to 11:568/570 of 8hs0A
Q9LIR4 Dihydroxy-acid dehydratase, chloroplastic; AthDHAD; DAD; EC 4.2.1.9 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
40% identity, 96% coverage: 2:567/588 of query aligns to 50:606/608 of Q9LIR4
Q1JUQ1 L-arabonate dehydratase; L-arabinonate dehydratase; EC 4.2.1.25 from Azospirillum brasilense (see paper)
36% identity, 91% coverage: 21:553/588 of query aligns to 24:547/583 of Q1JUQ1
B5ZZ34 L-arabinonate dehydratase; ArDHT; D-fuconate dehydratase; Galactonate dehydratase; L-arabonate dehydratase; EC 4.2.1.25; EC 4.2.1.67; EC 4.2.1.6 from Rhizobium leguminosarum bv. trifolii (strain WSM2304) (see 2 papers)
34% identity, 91% coverage: 6:538/588 of query aligns to 10:534/579 of B5ZZ34
5j85A Ser480ala mutant of l-arabinonate dehydratase (see paper)
34% identity, 91% coverage: 6:538/588 of query aligns to 7:531/576 of 5j85A
8epzA Crystal structure of fe-s cluster-dependent dehydratase from paralcaligenes ureilyticus in complex with mn
32% identity, 93% coverage: 21:565/588 of query aligns to 19:551/569 of 8epzA
8ej0A Crystal structure of fe-s cluster-dependent dehydratase from paralcaligenes ureilyticus in complex with mg
32% identity, 93% coverage: 21:565/588 of query aligns to 18:550/568 of 8ej0A
7m3kA Crystal structure of galactonate dehydratase from brucella melitensis biovar abortus 2308
32% identity, 86% coverage: 29:536/588 of query aligns to 28:536/587 of 7m3kA
Q9A9Z2 D-xylonate dehydratase; XyDHT; Gluconate dehydratase; EC 4.2.1.82; EC 4.2.1.39 from Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus) (see 2 papers)
34% identity, 85% coverage: 37:538/588 of query aligns to 49:548/595 of Q9A9Z2
5oynA Crystal structure of d-xylonate dehydratase in holo-form (see paper)
34% identity, 85% coverage: 37:538/588 of query aligns to 43:542/589 of 5oynA
>BPHYT_RS25650 FitnessBrowser__BFirm:BPHYT_RS25650
MTNLHKHRSRRVTDGVTRAPHRAFLRATGLDDESMQKPFVAIVDTFGENTPCSMSLNQVS
DNVRLGIAAGGGVPIRGSAISVSDGTSMNHSGMRMSLVSREVVADSVELFVRAHNYDALI
GVAGCDKTLPGILMGMVRVNVPGVFLFGGAMLPGVAPGQLPGGAGTGLQRQSTILTTIEA
VGTTQRGDMSRAQLDAIEKQCTPTAGSCPGQFTANTMAMVAETLGLAPLGSAMVPAVYSE
RIAIARRAGETVMRILTQGGPLPRDLVTMESLENACAAVAATGGSTNAALHIPAIANEAG
IRFALDDVQRVFAKIPLIGDLQPGGRYLAQDLHHAGGVPAVLNALLAGGFLHGDVPAFGG
GTLAEALSAFSGPDGIVVRPCDEPLGENGGLVILRGNLAPDGACLKIAGLKSLSFTGAVR
VFECEEDCMAVVAARDYREGDVLVIRNEGPKGGPGMREMLGVTAAIYGQGMGEKVALLTD
GRFSGATRGMCIGYVGPEAAAGGPIGLLRNDDRVHIDARAGILRVDLSDDELARRRADAP
ARASRRLAGVLEKYEALVRPAHLGAVTHSGNVEWPYDEPTPGDDGAAA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory