Comparing BPHYT_RS27200 FitnessBrowser__BFirm:BPHYT_RS27200 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
7ezlA Rice l-galactose dehydrogenase (holo form)
26% identity, 88% coverage: 12:307/338 of query aligns to 11:281/318 of 7ezlA
7eziA Rice l-galactose dehydrogenase (apo form)
26% identity, 88% coverage: 12:307/338 of query aligns to 16:286/323 of 7eziA
7svqA Crystal structure of l-galactose dehydrogenase from spinacia oleracea in complex with NAD+ (see paper)
23% identity, 88% coverage: 9:307/338 of query aligns to 7:280/315 of 7svqA
1pz0A Structure of NADPH-dependent family 11 aldo-keto reductase akr11a(holo) (see paper)
25% identity, 91% coverage: 9:316/338 of query aligns to 5:299/311 of 1pz0A
1ynqB Aldo-keto reductase akr11c1 from bacillus halodurans (holo form) (see paper)
27% identity, 95% coverage: 4:323/338 of query aligns to 2:286/298 of 1ynqB
1ynpB Aldo-keto reductase akr11c1 from bacillus halodurans (apo form) (see paper)
27% identity, 95% coverage: 4:323/338 of query aligns to 2:286/298 of 1ynpB
P46336 Aldo-keto reductase IolS; AKR11A; Vegetative protein 147; VEG147; EC 1.1.1.- from Bacillus subtilis (strain 168) (see paper)
25% identity, 91% coverage: 9:316/338 of query aligns to 6:300/310 of P46336
1ynpA Aldo-keto reductase akr11c1 from bacillus halodurans (apo form) (see paper)
26% identity, 92% coverage: 12:323/338 of query aligns to 10:271/283 of 1ynpA
Sites not aligning to the query:
P77256 NADH-specific methylglyoxal reductase; AKR11B2; EC 1.1.1.- from Escherichia coli (strain K12) (see paper)
23% identity, 93% coverage: 9:323/338 of query aligns to 6:326/326 of P77256
6ow0B Crystal structure of mithramycin 3-side chain keto-reductase mtmw in complex with NAD+ and peg (see paper)
26% identity, 88% coverage: 7:305/338 of query aligns to 4:272/301 of 6ow0B
4exaF Crystal structure of the pa4992, the putative aldo-keto reductase from pseudomona aeruginosa (see paper)
27% identity, 80% coverage: 12:281/338 of query aligns to 19:259/259 of 4exaF
3n6qD Crystal structure of yghz from e. Coli (see paper)
24% identity, 89% coverage: 11:311/338 of query aligns to 19:293/315 of 3n6qD
Q3L181 Perakine reductase; EC 1.1.1.317 from Rauvolfia serpentina (Serpentine wood) (Ophioxylon serpentinum) (see paper)
29% identity, 40% coverage: 9:144/338 of query aligns to 6:128/337 of Q3L181
3erpA Structure of idp01002, a putative oxidoreductase from and essential gene of salmonella typhimurium (see paper)
23% identity, 88% coverage: 11:309/338 of query aligns to 19:291/312 of 3erpA
5t79A X-ray crystal structure of a novel aldo-keto reductases for the biocatalytic conversion of 3-hydroxybutanal to 1,3-butanediol (see paper)
23% identity, 88% coverage: 11:309/338 of query aligns to 20:296/315 of 5t79A
1lqaA Tas protein from escherichia coli in complex with NADPH (see paper)
25% identity, 93% coverage: 7:322/338 of query aligns to 4:335/346 of 1lqaA
P0A9T4 Protein tas from Escherichia coli (strain K12) (see paper)
25% identity, 93% coverage: 7:322/338 of query aligns to 4:335/346 of P0A9T4
6ow0A Crystal structure of mithramycin 3-side chain keto-reductase mtmw in complex with NAD+ and peg (see paper)
25% identity, 88% coverage: 7:305/338 of query aligns to 4:296/323 of 6ow0A
4aubE The complex structure of the bacterial aldo-keto reductase akr14a1 with NADP and citrate (see paper)
24% identity, 92% coverage: 11:320/338 of query aligns to 19:293/297 of 4aubE
4aubB The complex structure of the bacterial aldo-keto reductase akr14a1 with NADP and citrate (see paper)
24% identity, 89% coverage: 11:311/338 of query aligns to 18:306/335 of 4aubB
Sites not aligning to the query:
>BPHYT_RS27200 FitnessBrowser__BFirm:BPHYT_RS27200
MKAIATHALPRSGLAMTTLGLGCSQLGGLYKPMSAAEANALVDWAWDAGIRYFDTAPFYG
YTLSERRVGHSLQMRERERYVLSTKVGRLMRPDATVQPGDDGWAHPLPFRPRFDYTFDGI
MRSYEDSQQRLGMQTIDVLYVHDIGAATHGDQHSRYWEQLTRGGGFRALAELRDCHAVSA
IGLGINEWQVAVDAMQEADLDLILLAGRYTLLEQEALAPLLDRCARNDTRIVAGGVFNSG
VLVGNGKFNYADAPVEVADRVARLAAVCTRFEVPLAAAALQFPLAHPAVVSCVIGASSIA
QLQQNIAWLETPLPPELWQALQREGLIAESAPVPEVCA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory