Comparing BPHYT_RS34440 FitnessBrowser__BFirm:BPHYT_RS34440 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
6pk1A Alanine-glyoxylate aminotransferase 1 (agt1) from arabidopsis thaliana in presence of serine (see paper)
46% identity, 95% coverage: 10:395/406 of query aligns to 6:390/399 of 6pk1A
Q56YA5 Serine--glyoxylate aminotransferase; Alanine--glyoxylate aminotransferase; AGT; Asparagine aminotransferase; Serine--pyruvate aminotransferase; EC 2.6.1.45; EC 2.6.1.44; EC 2.6.1.-; EC 2.6.1.51 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
46% identity, 95% coverage: 10:395/406 of query aligns to 8:392/401 of Q56YA5
6pk3B Alanine-glyoxylate aminotransferase 1 (agt1) from arabidopsis thaliana (see paper)
46% identity, 95% coverage: 10:395/406 of query aligns to 7:391/400 of 6pk3B
2dr1A Crystal structure of the ph1308 protein from pyrococcus horikoshii ot3
31% identity, 85% coverage: 11:356/406 of query aligns to 16:354/381 of 2dr1A
3islA Crystal structure of ureidoglycine-glyoxylate aminotransferase (pucg) from bacillus subtilis
30% identity, 88% coverage: 14:371/406 of query aligns to 10:362/387 of 3islA
O32148 (S)-ureidoglycine--glyoxylate transaminase; UGXT; (S)-ureidoglycine--glyoxylate aminotransferase; Purine catabolism protein PucG; EC 2.6.1.112 from Bacillus subtilis (strain 168) (see paper)
29% identity, 88% coverage: 14:371/406 of query aligns to 14:384/416 of O32148
1vjoA Crystal structure of alanine--glyoxylate aminotransferase (alr1004) from nostoc sp. At 1.70 a resolution (see paper)
32% identity, 84% coverage: 17:356/406 of query aligns to 24:357/377 of 1vjoA
Q0IG34 3-hydroxykynurenine transaminase; 3-hydroxykynurenine transaminase and alanine--glyoxylate aminotransferase; Ae-HKT/AGT; Alanine--glyoxylate aminotransferase; EC 2.6.1.63; EC 2.6.1.44 from Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
30% identity, 85% coverage: 17:361/406 of query aligns to 24:366/400 of Q0IG34
2ch2A Structure of the anopheles gambiae 3-hydroxykynurenine transaminase in complex with inhibitor (see paper)
30% identity, 85% coverage: 17:361/406 of query aligns to 22:364/387 of 2ch2A
Q7PRG3 3-hydroxykynurenine transaminase; AgHKT; Alanine--glyoxylate aminotransferase; EC 2.6.1.63; EC 2.6.1.44 from Anopheles gambiae (African malaria mosquito) (see paper)
30% identity, 85% coverage: 17:361/406 of query aligns to 24:366/396 of Q7PRG3
2ch1A Structure of anopheles gambiae 3-hydroxykynurenine transaminase (see paper)
30% identity, 85% coverage: 17:361/406 of query aligns to 23:365/388 of 2ch1A
6mfbD Crystal structure of 3-hydroxykynurenine transaminase from aedes aegypti
30% identity, 85% coverage: 17:361/406 of query aligns to 24:366/386 of 6mfbD
Q3LSM4 Alanine--glyoxylate aminotransferase; EC 2.6.1.44 from Aedes aegypti (Yellowfever mosquito) (Culex aegypti) (see paper)
30% identity, 85% coverage: 13:356/406 of query aligns to 21:361/393 of Q3LSM4
2z9xA Crystal structure of pyridoxamine-pyruvate aminotransferase complexed with pyridoxyl-l-alanine (see paper)
30% identity, 83% coverage: 18:356/406 of query aligns to 16:349/392 of 2z9xA
2z9wA Crystal structure of pyridoxamine-pyruvate aminotransferase complexed with pyridoxal (see paper)
30% identity, 83% coverage: 18:356/406 of query aligns to 16:349/392 of 2z9wA
2z9vA Crystal structure of pyridoxamine-pyruvate aminotransferase complexed with pyridoxamine (see paper)
30% identity, 83% coverage: 18:356/406 of query aligns to 16:349/392 of 2z9vA
Q988B8 Pyridoxamine--pyruvate transaminase; Pyridoxamine-pyruvate aminotransferase; EC 2.6.1.30 from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (Mesorhizobium loti (strain MAFF 303099)) (see 2 papers)
30% identity, 83% coverage: 18:356/406 of query aligns to 17:350/393 of Q988B8
Sites not aligning to the query:
2huuA Crystal structure of aedes aegypti alanine glyoxylate aminotransferase in complex with alanine (see paper)
30% identity, 85% coverage: 13:356/406 of query aligns to 21:361/385 of 2huuA
2huiA Crystal structure of aedes aegypti alanine glyoxylate aminotransferase in complex with glyoxylic acid (see paper)
30% identity, 85% coverage: 13:356/406 of query aligns to 21:361/385 of 2huiA
2hufA Crystal structure of aedes aegypti alanine glyoxylate aminotransferase (see paper)
30% identity, 85% coverage: 13:356/406 of query aligns to 21:361/385 of 2hufA
>BPHYT_RS34440 FitnessBrowser__BFirm:BPHYT_RS34440
MLKLDFHPAGRHFLQIPGPSPVPDRILRAMSYPTIDHRGPEFGELGLKVLDGIKKIFKTQ
QPVVIYPASGTGAWEAALSNTLSPGDHVLMFETGHFATLWQKMAESLGLKPEFLGLPGIE
GWRRGVQPQMIEERLRADTQHAIKAVCVVHNETSTGVTSDIAAVRRAIDAAGHPALLLVD
TISGLACADYRHDEWGVDVTVSGSQKGLMLPPGISFNAISPKAVAASKQARLPRSFWDWT
DIVEMNKTGYWPYTPNTNLLYGLNEALEMILGEGLDNVFARHERLAEATRRAVRAWGLEI
QCADPSVYSPVLTGVMMPDGIDADAVRKLIYERFDMSLGTGLGKMKGRMFRIGHLGDCND
LMLLATLAGCEMGLRLAGVPLKESGLPAAMEWLSQPTKASGLKAAA
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory