Comparing BWI76_RS03945 FitnessBrowser__Koxy:BWI76_RS03945 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 6 hits to proteins with known functional sites (download)
4im7A Crystal structure of fructuronate reductase (ydfi) from e. Coli cft073 (efi target efi-506389) complexed with nadh and d-mannonate
27% identity, 96% coverage: 17:480/481 of query aligns to 20:479/483 of 4im7A
7rk5B Mannitol-2-dehydrogenase bound to nadh from aspergillus fumigatus
24% identity, 96% coverage: 19:480/481 of query aligns to 37:496/501 of 7rk5B
1m2wA Pseudomonas fluorescens mannitol 2-dehydrogenase ternary complex with NAD and d-mannitol (see paper)
25% identity, 75% coverage: 20:381/481 of query aligns to 31:399/492 of 1m2wA
1lj8A Crystal structure of mannitol dehydrogenase in complex with NAD (see paper)
25% identity, 75% coverage: 20:381/481 of query aligns to 31:399/492 of 1lj8A
P09424 Mannitol-1-phosphate 5-dehydrogenase; EC 1.1.1.17 from Escherichia coli (strain K12) (see paper)
24% identity, 82% coverage: 17:411/481 of query aligns to 2:345/382 of P09424
Q4X1A4 Mannitol-1-phosphate 5-dehydrogenase; M1PDH; MPD; MPDH; EC 1.1.1.17 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see paper)
21% identity, 70% coverage: 17:352/481 of query aligns to 4:287/388 of Q4X1A4
>BWI76_RS03945 FitnessBrowser__Koxy:BWI76_RS03945
MKSLNRQDFPGPQYPTRAIQFGEGNFLRAFIDWQLDLLNEKTDLAAGVTIVRPINTEFPP
SLNTQDGLYTTVIRGLDERGEAVSEARIIRSVNNEINPWQDFAGYLALARNPAIAFVFSN
TTEAGISYHAGDRPDDKPPVSFPAKLAQLLLERFRHFNGAADKGWTIIPCELIDYNGEAL
KALVLRYAEEWQLPAAFRDWVETANTFCSTLVDRIVTGYPRDEAEKLEAELGYHDAFLDT
AEYFWLFVIQGPRALAEKLRLDRCPLNIHIVEDIRPYKERKVAILNGAHTALVPVAWLCG
VDTVGEAMRDEAIRHYVQQTIDEEIIPALDLPADELRQFADAVTGRFLNPFIRHQLLSIA
LNGMTKFRTRILPQLLANTRQHGVIPPRLTFALAALIAFYRGQRDGQTYPLQDDDVWLTR
FAEGWAQVAQGRPLGELVTEVLQDTAHWGEDLTAIPGLAEQVTRYLEVILSAGMREALSR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory