Comparing BWI76_RS04700 FitnessBrowser__Koxy:BWI76_RS04700 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 12 hits to proteins with known functional sites (download)
2pc6A Crystal structure of putative acetolactate synthase- small subunit from nitrosomonas europaea (see paper)
59% identity, 100% coverage: 1:163/163 of query aligns to 2:163/164 of 2pc6A
P9WKJ3 Putative acetolactate synthase small subunit; Acetohydroxy-acid synthase small subunit; AHAS; ALS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
45% identity, 96% coverage: 5:160/163 of query aligns to 8:162/168 of P9WKJ3
A0QUX7 Acetolactate synthase small subunit; Acetohydroxy-acid synthase small subunit; AHAS; ALS; EC 2.2.1.6 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
42% identity, 96% coverage: 5:160/163 of query aligns to 10:164/170 of A0QUX7
Q9FFF4 Acetolactate synthase small subunit 2, chloroplastic; ALS-interacting protein 3; Acetohydroxy-acid synthase small subunit 2; Protein valine-tolerant 1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
39% identity, 96% coverage: 2:157/163 of query aligns to 76:228/477 of Q9FFF4
Sites not aligning to the query:
6vz8F Arabidopsis thaliana acetohydroxyacid synthase complex with valine bound (see paper)
37% identity, 96% coverage: 2:157/163 of query aligns to 4:156/159 of 6vz8F
Q93YZ7 Acetolactate synthase small subunit 1, chloroplastic; ALS-interacting protein 1; Acetohydroxyacid synthase small subunit 1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
37% identity, 96% coverage: 2:157/163 of query aligns to 86:238/491 of Q93YZ7
Sites not aligning to the query:
6vz8G Arabidopsis thaliana acetohydroxyacid synthase complex with valine bound (see paper)
39% identity, 94% coverage: 5:157/163 of query aligns to 6:157/159 of 6vz8G
O60086 Probable acetolactate synthase small subunit; Acetohydroxy-acid synthase small subunit; AHAS; ALS from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
28% identity, 96% coverage: 2:158/163 of query aligns to 70:265/289 of O60086
Sites not aligning to the query:
6wo1B Hybrid acetohydroxyacid synthase complex structure with cryptococcus neoformans ahas catalytic subunit and saccharomyces cerevisiae ahas regulatory subunit (see paper)
28% identity, 96% coverage: 2:157/163 of query aligns to 4:195/197 of 6wo1B
6u9dL Saccharomyces cerevisiae acetohydroxyacid synthase (see paper)
27% identity, 96% coverage: 2:157/163 of query aligns to 37:240/255 of 6u9dL
5yumA Crystallographic structures of ilvn.Val/ile complexes:conformational selectivity for feedback inhibition of ahass (see paper)
34% identity, 43% coverage: 4:73/163 of query aligns to 5:73/91 of 5yumA
5yppE Crystal structure of ilvn.Val-1a (see paper)
34% identity, 43% coverage: 4:73/163 of query aligns to 5:73/91 of 5yppE
>BWI76_RS04700 FitnessBrowser__Koxy:BWI76_RS04700
MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDEKAIEQI
EKQLHKLVDVLRVNELGQGAHVEREIMLVKVQASGYGRDEVKRNTEIFRGQIIDVTPSIY
TVQLAGTSDKLDAFLASLRDVARIVEVARSGVVGLSRGDKIMR
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory