Comparing BWI76_RS05650 FitnessBrowser__Koxy:BWI76_RS05650 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 4 hits to proteins with known functional sites (download)
4eacC Crystal structure of mannonate dehydratase from escherichia coli strain k12 (see paper)
94% identity, 100% coverage: 1:394/394 of query aligns to 3:396/396 of 4eacC
4eayA Crystal structures of mannonate dehydratase from escherichia coli strain k12 complexed with d-mannonate (see paper)
94% identity, 100% coverage: 1:393/394 of query aligns to 3:395/395 of 4eayA
3dbnA Crystal structure of the streptoccocus suis serotype2 d- mannonate dehydratase in complex with its substrate (see paper)
37% identity, 99% coverage: 1:390/394 of query aligns to 3:335/349 of 3dbnA
3bdkA Crystal structure of streptococcus suis mannonate dehydratase complexed with substrate analogue
37% identity, 99% coverage: 1:390/394 of query aligns to 3:335/349 of 3bdkA
>BWI76_RS05650 FitnessBrowser__Koxy:BWI76_RS05650
MEQTWRWYGPNDPVTLADVRQAGATGVVTALHHIPNGEVWTVDEILKRKAIVEEAGLVWS
VVESVPIHEEIKTHTGNYAQWIANYQQSLRNLAQCGIRTVCYNFMPVLDWTRTDLEYVLP
DGSKALRFDQIEFAAFELHILKRPGAEADYTAEEVAQANQRFAAMSDEDKARLTRNIIAG
LPGAEEGYTLDQFRQHLATYKDIDKAALRENFAVFMKAIIPVAEEAGVRMAVHPDDPPRP
ILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLR
STLREENPKTFHEAAHLHGDVDMYEVVKAIVEEEHRRKAEGKEDLIPMRPDHGHQMLDDL
KKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSR
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory