Comparing BWI76_RS09125 FitnessBrowser__Koxy:BWI76_RS09125 to proteins with known functional sites using BLASTp with E ≤ 0.001.
Or try Sites on a Tree, PaperBLAST, Conserved Domains, or compare to all protein structures
Found 6 hits to proteins with known functional sites (download)
P16552 Raffinose permease; Raf permease from Escherichia coli (see paper)
38% identity, 94% coverage: 24:414/414 of query aligns to 27:423/425 of P16552
2y5yA Crystal structure of lacy in complex with an affinity inactivator (see paper)
41% identity, 88% coverage: 29:393/414 of query aligns to 26:383/386 of 2y5yA
Sites not aligning to the query:
P02920 Lactose permease; Lactose-proton symport from Escherichia coli (strain K12) (see 3 papers)
40% identity, 88% coverage: 29:393/414 of query aligns to 29:400/417 of P02920
Sites not aligning to the query:
6vbgB Lactose permease complex with thiodigalactoside and nanobody 9043 (see paper)
40% identity, 88% coverage: 29:393/414 of query aligns to 29:388/397 of 6vbgB
Sites not aligning to the query:
4zyrA Crystal structure of e. Coli lactose permease g46w/g262w bound to p- nitrophenyl alpha-d-galactopyranoside (alpha-npg) (see paper)
40% identity, 88% coverage: 29:393/414 of query aligns to 24:379/387 of 4zyrA
Sites not aligning to the query:
P96517 Melibiose permease; Melibiose transporter MelY from Enterobacter cloacae subsp. cloacae (strain ATCC 13047 / DSM 30054 / NBRC 13535 / NCTC 10005 / WDCM 00083 / NCDC 279-56) (see 2 papers)
39% identity, 91% coverage: 24:398/414 of query aligns to 29:410/425 of P96517
>BWI76_RS09125 FitnessBrowser__Koxy:BWI76_RS09125
MITPGKRNYILLSLFDFLYLFAWSSTMAFFVIWTTQHLGISATKTGLLYSVNAFIALLMQ
PFFGFISDKFGLKKRLIWILVAMLLPVGPFFIYLYAPLLVHSFWLGALLGGVYLGIIFNS
GCGVIDSYIDKISRRYQFEYGRVRMWGSLGWAAAAWIVGKYIDSNPNLAFWLASVAIVIA
AICFMLTKIELTEAEMQKSSALKVSHALELAKNGQFWMLLVFTLFVTQIYDTYDQQFAQY
FSLQFSTPEEGNRWYGILASIQVCGETLFLCLMPWFVNRTGAKWALIIAGLIMSVRIVGS
AIPLGPVWIGAVKMMHALEKPLILVSVFKFIAANFDNKLSSTVYLLVLFVASIATAIYSP
LAGYLYDTIGFAHTYYILGGIAGLFTLISVFTLRDNREPTAPGAAPGAGVAQSH
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory