Comparing BWI76_RS09865 FitnessBrowser__Koxy:BWI76_RS09865 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
2xf4A Crystal structure of salmonella enterica serovar typhimurium ycbl (see paper)
89% identity, 98% coverage: 1:210/215 of query aligns to 1:210/210 of 2xf4A
7ev5A Crystal structure of bleg-1 b3 metallo-beta-lactamase (see paper)
35% identity, 96% coverage: 3:208/215 of query aligns to 2:207/209 of 7ev5A
2zwrB Crystal structure of ttha1623 from thermus thermophilus hb8 (see paper)
39% identity, 96% coverage: 4:209/215 of query aligns to 2:201/207 of 2zwrB
2zziA Crystal structure of ttha1623 in a di-iron-bound form (see paper)
39% identity, 95% coverage: 5:208/215 of query aligns to 1:198/198 of 2zziA
7l0bA Crystal structure of hydroxyacyl glutathione hydrolase (glob) from staphylococcus aureus, apoenzyme (see paper)
34% identity, 96% coverage: 4:209/215 of query aligns to 3:201/202 of 7l0bA
3tp9A Crystal structure of alicyclobacillus acidocaldarius protein with beta-lactamase and rhodanese domains
31% identity, 97% coverage: 1:209/215 of query aligns to 3:227/473 of 3tp9A
4ysbA Crystal structure of ethe1 from myxococcus xanthus (see paper)
30% identity, 88% coverage: 17:206/215 of query aligns to 17:188/225 of 4ysbA
3r2uB 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
29% identity, 91% coverage: 11:205/215 of query aligns to 15:210/336 of 3r2uB
Sites not aligning to the query:
6sg9FL uS3m (see paper)
27% identity, 93% coverage: 11:209/215 of query aligns to 62:298/320 of 6sg9FL
Sites not aligning to the query:
2gcuA X-ray structure of gene product from arabidopsis thaliana at1g53580 (see paper)
28% identity, 89% coverage: 24:215/215 of query aligns to 28:210/244 of 2gcuA
Q9C8L4 Persulfide dioxygenase ETHE1 homolog, mitochondrial; Glyoxalase II; Glx II; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
28% identity, 89% coverage: 24:215/215 of query aligns to 77:259/294 of Q9C8L4
2q42A Ensemble refinement of the protein crystal structure of glyoxalase ii from arabidopsis thaliana gene at2g31350 (see paper)
30% identity, 80% coverage: 21:192/215 of query aligns to 20:169/254 of 2q42A
Q9SID3 Hydroxyacylglutathione hydrolase 2, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
31% identity, 80% coverage: 21:192/215 of query aligns to 90:239/324 of Q9SID3
5ve5A Crystal structure of persulfide dioxygenase rhodanese fusion protein with rhodanese domain inactivating mutation (c314s) from burkholderia phytofirmans in complex with glutathione (see paper)
29% identity, 88% coverage: 23:212/215 of query aligns to 26:200/350 of 5ve5A
Sites not aligning to the query:
3r2uA 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
27% identity, 91% coverage: 11:205/215 of query aligns to 13:222/348 of 3r2uA
4chlB Human ethylmalonic encephalopathy protein 1 (hethe1) (see paper)
27% identity, 91% coverage: 14:208/215 of query aligns to 17:199/237 of 4chlB
O95571 Persulfide dioxygenase ETHE1, mitochondrial; Ethylmalonic encephalopathy protein 1; Hepatoma subtracted clone one protein; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Homo sapiens (Human) (see 4 papers)
27% identity, 91% coverage: 14:208/215 of query aligns to 33:215/254 of O95571
Sites not aligning to the query:
8ewoA Crystal structure of putative glyoxylase ii from pseudomonas aeruginosa
36% identity, 69% coverage: 12:160/215 of query aligns to 10:142/259 of 8ewoA
Sites not aligning to the query:
5aebB Crystal structure of the class b3 di-zinc metallo-beta-lactamase lra- 12 from an alaskan soil metagenome. (see paper)
30% identity, 63% coverage: 15:150/215 of query aligns to 36:181/266 of 5aebB
Sites not aligning to the query:
4yslA Crystal structure of sdoa from pseudomonas putida in complex with glutathione (see paper)
27% identity, 88% coverage: 17:205/215 of query aligns to 23:234/294 of 4yslA
Sites not aligning to the query:
>BWI76_RS09865 FitnessBrowser__Koxy:BWI76_RS09865
MNYRIIPVTAFAQNCSLIWCEQTKLAALVDPGGDAERIKQEVAAAGVSLMQILLTHGHLD
HVGAAAELAQHYGVPIIGPEKEDEFWLEGLPAQSRMFGLEDCQPLQPDRWLNEGDAVSVG
NISLQVLHCPGHTPGHVVFFDPACRLLISGDVIFKGGVGRSDFPRGDHNQLIDAIKRKLL
PLGDDVSFIPGHGPMSTLGYERLHNPFLQDEMPVW
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SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory