Comparing BWI76_RS14875 FitnessBrowser__Koxy:BWI76_RS14875 to proteins with known functional sites using BLASTp with E ≤ 0.001.
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Found 20 (the maximum) hits to proteins with known functional sites (download)
4wjmA Crystal structure of fructokinase from brucella abortus 2308 with bound amppnp
64% identity, 97% coverage: 1:306/314 of query aligns to 7:312/312 of 4wjmA
7fcaD Pfkb(mycobacterium marinum) (see paper)
32% identity, 94% coverage: 3:298/314 of query aligns to 5:282/282 of 7fcaD
3lkiB Crystal structure of fructokinase with bound atp from xylella fastidiosa
29% identity, 95% coverage: 2:298/314 of query aligns to 5:303/322 of 3lkiB
Q8ZKR2 Aminoimidazole riboside kinase; AIRs kinase; EC 2.7.1.223 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
29% identity, 84% coverage: 6:270/314 of query aligns to 11:273/319 of Q8ZKR2
Sites not aligning to the query:
5eynA Crystal structure of fructokinase from vibrio cholerae o395 in fructose, adp, beryllium trifluoride and calcium ion bound form
29% identity, 83% coverage: 2:262/314 of query aligns to 4:262/306 of 5eynA
Sites not aligning to the query:
5yggA Crystal structure of fructokinase double-mutant (t261c-h108c) from vibrio cholerae o395 in fructose, adp and potassium ion bound form (see paper)
29% identity, 83% coverage: 2:262/314 of query aligns to 8:266/310 of 5yggA
Sites not aligning to the query:
1tz6A Crystal structure of aminoimidazole riboside kinase from salmonella enterica complexed with aminoimidazole riboside and atp analog (see paper)
29% identity, 84% coverage: 6:270/314 of query aligns to 7:262/297 of 1tz6A
Sites not aligning to the query:
1tz3A Crystal structure of aminoimidazole riboside kinase complexed with aminoimidazole riboside (see paper)
29% identity, 84% coverage: 6:270/314 of query aligns to 7:262/299 of 1tz3A
1v1aA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound 2- keto-3-deoxygluconate and adp (see paper)
30% identity, 82% coverage: 2:258/314 of query aligns to 4:260/301 of 1v1aA
Sites not aligning to the query:
1v1bA 2-keto-3-deoxygluconate kinase from thermus thermophilus with bound atp (see paper)
30% identity, 82% coverage: 2:258/314 of query aligns to 4:260/300 of 1v1bA
Sites not aligning to the query:
Q53W83 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
30% identity, 82% coverage: 2:258/314 of query aligns to 4:260/309 of Q53W83
Sites not aligning to the query:
3gbuA Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with atp
25% identity, 82% coverage: 1:259/314 of query aligns to 1:255/302 of 3gbuA
Sites not aligning to the query:
3ih0A Crystal structure of an uncharacterized sugar kinase ph1459 from pyrococcus horikoshii in complex with amp-pnp
25% identity, 82% coverage: 1:259/314 of query aligns to 2:256/304 of 3ih0A
Sites not aligning to the query:
3iq0B Crystal structure of a putative ribokinase ii in complex with atp and mg+2 from e.Coli
27% identity, 69% coverage: 41:257/314 of query aligns to 47:263/308 of 3iq0B
Sites not aligning to the query:
8cqxA Ribokinase from t.Sp mutant a92g
25% identity, 98% coverage: 1:308/314 of query aligns to 1:296/300 of 8cqxA
P0A9J6 Ribokinase; RK; EC 2.7.1.15 from Escherichia coli (strain K12) (see 3 papers)
24% identity, 90% coverage: 24:306/314 of query aligns to 36:301/309 of P0A9J6
Sites not aligning to the query:
1rk2A E. Coli ribokinase complexed with ribose and adp, solved in space group p212121 (see paper)
24% identity, 90% coverage: 24:306/314 of query aligns to 33:298/305 of 1rk2A
Sites not aligning to the query:
1gqtB Activation of ribokinase by monovalent cations (see paper)
24% identity, 90% coverage: 24:306/314 of query aligns to 35:300/307 of 1gqtB
Sites not aligning to the query:
4eumA Crystal structure of a sugar kinase (target efi-502132) from oceanicola granulosus with bound amp, crystal form ii
27% identity, 82% coverage: 2:259/314 of query aligns to 17:272/294 of 4eumA
Sites not aligning to the query:
3in1A Crystal structure of a putative ribokinase in complex with adp from e.Coli
27% identity, 82% coverage: 2:259/314 of query aligns to 4:268/312 of 3in1A
Sites not aligning to the query:
>BWI76_RS14875 FitnessBrowser__Koxy:BWI76_RS14875
MILCCGEALIDMLPCQSRENDPAFTPCVGGAAFNTAVALGRQGMAVSLFSGLSDDFMGDM
LRHTLDASGVDYSPSTRAPLPTTLAFVRLVGGQARYTFYDENSAGRMLRESDLPELRDDV
AAVLFGCISLIAEPCGSVYETLMAREAPRRVMYLDPNIREIFIADRQKHLARMRRMIALA
DIVKLSDEDLAWFAEPGEEHEVIRRWLALGPKLIVVTRGADGADAWTADFHLHVPAIRVA
VADTVGAGDTVNAGILASLSQAGLLEKEKLVTLSREQVRRAVDLGMRAAAVTVSRPGANP
PWDHELRSQQRPGL
Or try a new SitesBLAST search
SitesBLAST's database includes (1) SwissProt entries with experimentally-supported functional features; and (2) protein structures with bound ligands, from the BioLip database.
Lawrence Berkeley National Laboratory